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A new tetrazole-containing 2-amino-4,6-di(aziridin-1-yl)-1,3,5-triazine derivative: synthesis, interaction with DNA, and antitumor activity
({5-[4,6-Di(aziridin-1-yl)-1,3,5-triazin-2-yl]amino}-2,2-dimethyl-1,3-dioxan-5-yl)-methyl 2-(5-phenyl-2 H -tetrazol-2-yl)acetate was synthesized and...
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Phytochemicals, Biodegradation, Cytocompatibility and Wound Healing Profiles of Chitosan Film Embedded Green Synthesized Antibacterial ZnO/CuO Nanocomposite
Open wound ulcer treatment remains a great challenge in wound care management especially involving multi drug resistant (MDR) pathogen. Currently,...
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TargIDe: a machine-learning workflow for target identification of molecules with antibiofilm activity against Pseudomonas aeruginosa
Bacterial biofilms are a source of infectious human diseases and are heavily linked to antibiotic resistance. Pseudomonas aeruginosa is a...
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Recognition and Determination of Sulfonamides by Near-IR Fluorimetry Using Their Effect on the Rate of the Catalytic Oxidation of a Carbocyanine Dye by Hydrogen Peroxide
AbstractThe work aims at develo** fluorimetric methods used for bioassay to expand the range of the determined low-molecular-weight organic...
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Purity determination of pyributicarb by internal standard correction–high-performance liquid chromatography–quantitative nuclear magnetic resonance
An internal standard correction–high-performance liquid chromatography–quantitative nuclear magnetic resonance (ISC–HPLC–qNMR) procedure was...
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Recent Developments in the Treatment of Bacterial Pneumonia
Bacterial pneumonia acquired from either the community, hospital, ventilators, aspiration, or tuberculous organisms represents a threat to an...
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Thiophene-containing Schiff base polymers: synthesis, characterization, and anti-bacterial properties
We synthesized the Schiff bases and their polymers, which contain thiophene units. For the synthesis process, first, hydroxynaphthalene di- and...
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Investigation of radiolabelled chitosan nanoparticles bearing Cefpodoxime Proxetil, and in vitro antibacterial effect on Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli
This study aims to investigate radiolabeled Cefpodoxime Proxetil loaded chitosan (CP–CS) nanoparticles as nuclear imaging infection agent to...
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Effect of the tetracycline antibiotics on performance and microbial community of microbial fuel cell
AbstractThe adverse effect of tetracycline antibiotics on microbial activity is one of the serious risks for the biologic wastewater treatment...
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Drug delivery system in bone biology: an evolving platform for bone regeneration and bone infection management
Human osteology is the biomechanics science that deals with the study of minerals and non-collagenous organic components that shield human organs and...
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Molecular prevalence of resistance determinants, virulence factors and capsular serotypes among colistin resistance carbapenemase producing Klebsiella pneumoniae: a multi-centric retrospective study
The emergence of colistin-carbapenem-resistant Klebsiella pneumoniae (CCR-Kp) in bloodstream infection results in high mortality, and virulence...
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Synthesis of Different Types, Shapes, and Sizes of Nanocarriers Using Synthetic and Biological Approaches
The application of nanomaterials in different fields totally depends on their characteristics. Considering the impact of the synthesis method on the...
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Modification of acetazolamide synthesis: new derivatives and investigation of their biological properties
Acetazolamide 1 is a carbonic anhydrase inhibitor used in the medical treatment of glaucoma, epileptic seizure, idiopathic intracranial hypertension,...
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Synthesis and evaluation of biological activity of novel chromeno[4,3-b]quinolin-6-one derivatives by SO3H-tryptamine supported on Fe3O4@SiO2@CPS as recyclable and bioactive magnetic nanocatalyst
AbstractNew derivatives of chromeno[4,3-b]quinolin-6-one were synthesized using novel SO 3 H-tryptamine supported on Fe 3 O 4 @SiO 2 @CPS which could be...
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Synthesis of new 2-(5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-ylimino)thiazolidin-4-one derivatives as anti-MRSA and anti-H. pylori agents
In this work, we have synthesized twenty five new 2-(5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-ylimino)thiazolidin-4-one derivatives bearing an aryl...
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Synthesis, antimicrobial evaluation, and measurement of physical and thermo-acoustical parameters of novel 1,3,4-thiadiazole and benzo[d]imidazole scaffolds by ultrasonic studies
We prepared 15 novel series of 1,3,4-thiadiazole containing benzo[ d ]imidazole compounds for the development of potential antimicrobial agents ( 6a–o )....
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Microbiological quality and characteristics of isolated Escherichia coli in irrigation water used in Napa cabbage cultivation
To ensure the safety of Kimchi, the safety of Napa cabbage is the most important. Contaminated irrigation water can be a major cause of pathogens...
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Microbial Fuel Cell–Based Biosensors and Applications
The sustainable development of human society in today’s high-tech world depends on some form of eco-friendly energy source because existing...
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Antibiotic persistence and its impact on the environment
From boon molecules to molecules contributing to rising concern has been the sojourn of antibiotics. The problem of antibiotic contamination has...
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A Novel VIII Carboxylesterase with High Hydrolytic Activity Against Ampicillin from a Soil Metagenomic Library
A novel carboxylesterase gene, named dlfae4 , was discovered and sequenced from a soil metagenomic library. The dlfae4 gene was composed of 1017 base...
