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Metallocomplexes of fluoroquinolonecarboxylic acids
The survey reviews the data on the synthesis, structure and biological activity of fluoroquinolonecarboxylic acids metal chelates. The influence of...
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Synthesis of a dihydrotestosterone–ciprofloxacin conjugate: relationship between descriptors logP, π, R m , and V m and its antibacterial activity in S. aureus and E. coli
AbstractIn this work a dihydrotestosterone–ciprofloxacin conjugate was synthesized. The route involved preparation of a ciprofloxacin–ethylenediamine...
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Enhanced chemiluminescence of the luminol–KIO4 system by ZnS nanoparticles
The chemiluminescence (CL) intensity of the luminol–KIO 4 system is strongly enhanced by addition of zinc sulfide nanoparticles (ZnS-NPs) capped with...
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Simultaneous Quantitation of Quinolone Residues in Biological Fluid by CE Combined with Electrogenerated-Chemiluminescent Detection
A simple, rapid and sensitive method has been proposed for simultaneous electrogenerated-chemiluminescent detection of quinolone residues in...
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An Improved UPLC Method for Rapid Analysis of Levofloxacin in Human Plasma
A rapid, specific, and sensitive ultra-performance liquid chromatographic method for analysis of levofloxacin in human plasma has been developed and...
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Application of Turbulent Flow Chromatography Load Columns for the On-Line Analysis of Anti-Infectives in Wastewaters
We developed an on-line preconcentration liquid chromatography-tandem mass spectrometry method for the determination of the anti-infectives...
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Factor analysis of microbiological activity data and structural parameters of antibacterial quinolones
Factor analysis (FA) was performed on quinolone derivatives with antibacterial activity to model relationships between molecular descriptors and...
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Development and validation of a simultaneous extraction procedure for HPLC-MS quantification of daptomycin, amikacin, gentamicin, and rifampicin in human plasma
A simultaneous extraction method to measure daptomycin, amikacin, gentamicin, and rifampicin in human plasma, by high-performance liquid...
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Solid-phase microextraction with micellar desorption and HPLC-fluorescence detection for the analysis of fluoroquinolones residues in water samples
A sensitive and useful method based on solid-phase microextraction with micellar desorption (SPME-MD) coupled to HPLC with fluorescence detection was...
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The pH-dependent photochemistry of anthraquinone-2-sulfonate
The photochemistry of anthraquinone-2-sulfonate (AQ2S) was studied as a function of pH, combining laser flash photolysis and steady-state irradiation...
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High-Performance Liquid-Chromatographic Separation of Ofloxacin Using a Chiral Stationary Phase
A new chiral liquid-chromatographic method was developed for the enantiomeric separation of ofloxacin with a fluorescence detector. The enantiomers...
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Spectroscopic Studies on the Binding of a New Quinolone Antibacterial Agent: Sinafloxacin to DNA
The binding of sinafloxacin to DNA has been studied by fluorescence spectroscopy and UV-vis absorption spectroscopy. The variations in the...
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Electrochemiluminescence from tris(2,2′-bipyridyl) ruthenium (II) in the presence of aminocarboxylic acid co-reactants
Due to the highly sensitive electrochemiluminescence (ECL), tris(2,2′-bipyridyl) ruthenium(II) (Ru(bpy)
3 2+ ) is often used in the field of bioarrays... -
Fragmental descriptors in (Q)SAR: prediction of the assignment of organic compounds to pharmacological groups using the support vector machine approach
The structure—activity classification models for prediction of the assignment of organic compounds to 40 pharmacological groups were constructed in...
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Spectrophotometric Determination of Quinolone Antibiotics by an Association Complex Formation with Aluminum(III) and Erythrosin
A simple and sensitive spectrophotometric method for the determination of quinolone antibiotics was established based on an association complex...
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Chemiluminescence detection with separation techniques for bioanalytical applications
Chemiluminescence detection is known to be a sensitive, selective, and versatile method that can be used in combination with separation techniques...
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Synthesis and application of a new copper(II) complex containing oflx and leof
Two new copper(II) complexes of [Cu(Ofloxacin)(phen)(H 2 O)] · (NO 3 ) · 2H 2 O and [Cu(Levofloxacin)(phen)(H 2 O)] · (NO 3 ) · 2H 2 O were obtained and their...
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Otitis Media: A Review, with a Focus on Alternative Treatments
Otitis media (OM) is the accumulation of fluids in the middle ear, with or without symptoms of inflammation. The infection is caused by dysfunction...
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Grapefruit and Other Fruit Juices Interactions with Medicines
Objectives • Provide a comprehensive overview of the clinical interactions of grapefruit or other fruit juices with medications to cause altered...