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H3K27 acetylation-induced FSTL1 upregulation by P300/RUNX1 co-activation exacerbated autophagy-mediated neuronal damage and NF-κB-stimulated inflammation in Alzheimer’s disease
Follistatin-like protein 1 (FSTL1) has been demonstrated to participate in the pathogenesis of several neurological diseases. The current study...
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Summary (Types of Cardiovascular Diseases, Common Clinical Treatment Methods, and Defects of Cardiovascular Diseases)
Cardiovascular diseases include congenital heart disease, adult structural heart disease, atherosclerosis-based ischemic heart disease, arrhythmias...
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Spectrophotometric Approaches for Concurrent Estimation of Formoterol Fumarate Dihydrate and Fluticasone Propionate in their Binary Inhaler Combination
AbstractFormoterol fumarate dihydrate ( FFD ) is a long-acting β 2 agonist, while Fluticasone propionate ( FP ) is a synthetic glucocorticoid receptor...
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Macrophage-Targeted Nanomedicines
Macrophages are versatile cells of the innate immune system responsible for the control and progressions of a variety of autoimmune inflammatory,...
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Local delivery of gaseous signaling molecules for orthopedic disease therapy
Over the past decade, a proliferation of research has used nanoparticles to deliver gaseous signaling molecules for medical purposes. The discovery...
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Importance of Functional Foods Against Aging of Adult Stem Cells
Functional foods offer vital nutrients that can protect against different diseases in humans. These functional foods are exclusively full of...
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Biological Effects of Euterpe oleracea Extract (Açaí)
The açaí palm (Euterpe oleracea Mart., Arecaceae) is cultivated in central and tropical South America. The extract deriving from Açai is considered...
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Detection of COVID-19-related biomarkers by electrochemical biosensors and potential for diagnosis, prognosis, and prediction of the course of the disease in the context of personalized medicine
As a more efficient and effective way to address disease diagnosis and intervention, cutting-edge technologies, devices, therapeutic approaches, and...
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A semi-covalent molecularly imprinted electrochemical sensor for rapid and selective detection of tiotropium bromide
Tiotropium bromide (TIO) is a long-acting bronchodilator used in the treatment of chronic obstructive pulmonary disease (COPD) and asthma....
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The Inhibitory Functions of Sparstolonin B against Ambient Fine Particulate Matter Induced Lung Injury
Particulate matter, with an aerodynamic diameter equal to or less than 2.5 µm (PM 2.5 ), is an air pollutant that causes serious pulmonary injury when...
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Lipid-Based Drug Delivery for Pneumonia Treatment
Respiratory tract infections are a significant problem that severely impacts public health due to high morbidity and mortality rates. The causes of...
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Proteolysis and Deficiency of α1-Proteinase Inhibitor in SARS-CoV-2 Infection
The SARS-CoV-2 pandemic had stimulated the emergence of numerous publications on the α 1 -proteinase inhibitor (α 1 -PI, α 1 -antitrypsin), especially when...
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Metabolomics Approach to Identify Biomarkers of Epidemic Diseases
Epidemic diseases are a major public health concern for the growing economic world. Several metabolomics analysis efforts have been put toward human...
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Effects of Heavy Metal Contamination on the Safety of Halal Foodstuffs
Affording safe and healthy food is becoming a substantial demand. Islam cared about human health and focused on the need for strong, healthy Muslims...
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Alcohol Consumption and Health
The lowest risk of coronary heart disease (CHD) is seen at an alcohol intake of under 100 grams per week (one drink per day), but possibly less. This...
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Effects of Comorbidities on the Profile of Volatile Organic Compounds in the Exhaled Breath of Lung Cancer Patients
AbstractThe diagnostics of lung cancer by exhaled breath is a promising field in medicine; however, many patients with lung cancer have other...
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State of the Art in Integrated Biosensors for Organ-on-a-Chip Applications
Organ-on-a-chip (OoaC) is a potential emerging technology in the healthcare business based on bioengineered tissue constructions combined with...
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Food Insecurity , Nutrition, and the COVID-19 Pandemic
The Coronavirus disease 2019 (COVID-19) pandemic has impacted food systems, food insecurity, and nutrition in complex ways. Food insecurity is...
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Determination and Application of UHPLC-ESI-MS/MS Based Omega Fatty Acids on PUFA Filter Paper with Human Asthma Serum
We developed and validated a fast, sensitive, and accurate analytical method using ultra high-pressure liquid chromatography-electrospray ionization...
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Lycopene: Sources, Structure and Benefits
Carotenoids, pigments with the highest occurrence in nature, are responsible for the coloring yellow-orange of fruits and vegetables, fish,...