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Development of an innovative analytical method for forensic detection of cocaine, antidepressants, and metabolites in postmortem blood using magnetic nanoparticles
Cocaine and antidepressants rank high globally in substance consumption, emphasizing their impact on public health. The determination of these...
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Development and validation of a method for analysis of 25 cannabinoids in oral fluid and exhaled breath condensate
Currently, there is a significant demand in forensic toxicology for biomarkers of cannabis exposure that, unlike ∆ 9 -tetrahydrocannabinol, can...
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q-RASAR A Path to Predictive Cheminformatics
This brief offers an introduction to the fascinating new field of quantitative read-across structure-activity relationships (q-RASAR) as a...
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Naringenin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology
Nowadays, people tend to adopt natural health-improving sources into their diets due to the increased awareness on the toxicological side effects of... -
Simultaneous determination of 12 illicit drugs in hair sample by the nano-titania-modified covalent organic frameworks (NTM-COFs) on-line pass-through cleanup followed by UPLC-MS/MS
An effective analytical method using NTM-COFs on-line pass-through cleanup method and ultra-performance liquid chromatography-tandem mass...
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Phloretin: Advances on Resources, Biosynthesis Pathway, Bioavailability, Bioactivity, and Pharmacology
Phloretin is a dihydrochalcone found in various plant sources such as apples, strawberries, kumquat, pears, honeybush, and sweet tea. Numerous... -
Dual-loaded nano pesticide system based on industrial grade scaleable carrier materials with combinatory efficacy and improved safety
Repeated and widespread use of single chemical pesticides raises concerns about efficiency and safety, develo** multi-component synergistic...
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Carbenoid-involved reactions integrated with scaffold-based screening generates a Nav1.7 inhibitor
The discovery of selective Nav1.7 inhibitors is a promising approach for develo** anti-nociceptive drugs. In this study, we present a novel...
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Application of Planar Chromatography in Pharmaceutical, Clinical, and Toxicological Analysis
Many analytical techniques are used in bioanalysis; among them liquid chromatographic techniques belong to very popular ones. However planar liquid... -
Application of Planar Chromatography in Pharmaceutical, Clinical, and Toxicological Analysis
Many analytical techniques are used in bioanalysis; among them liquid chromatographic techniques belong to very popular ones. However planar liquid... -
Spectral and theoretical analysis of derivatives of 1,2,3,3-tetramethyl-3H-indolium iodide (TMI), a highly selective derivatization reagent of cyanide, and their utility for the analysis of cyanide concentrations in beverages
We develop a specific derivatization gas chromatography–mass spectrometry (GC–MS) method for cyanide using 1,2,3,3-tetramethyl-3 H -indium iodide as...
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Radioanalytical and nuclear techniques in trace metal toxicology research
Trace metal toxicology research aimed at generating human-relevant information for risk assessment requires the use of sensitive and sophisticated...
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Advances in Computational Toxicology Methodologies and Applications in Regulatory Science
This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and... -
Handbook of Dietary Flavonoids
This reference work summarizes the 100 most common flavonoids in our diet and provides an overview of their metabolism and potential health effects....
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Scutellarin: Bioactivities, Pharmacology, and Development as Promising Therapeutic Agents and Nutraceuticals
Scutellarin is a polyphenolic flavone with a characteristic C7-glucuronide substituent. It is widely distributed in nature, particularly in the mint... -
Ellagitannins
Ellagitannins (ET) are phytochemicals with potent antioxidant properties found in many natural foods. In particular, ETs have been studied... -
Sample preparation optimization of insects and zebrafish for whole-body mass spectrometry imaging
Appropriate sample preparation is one of the most critical steps in mass spectrometry imaging (MSI), which is closely associated with reproducible...
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Mode-of-Action-Guided, Molecular Modeling-Based Toxicity Prediction: A Novel Approach for In Silico Predictive Toxicology
Computational toxicologyComputational toxicology is a sub-discipline of toxicology concerned with the development and use of computer-based models... -
Speedy Gonzales analysis method in one drop of beverage, for crimes committed with drugs from three different groups
Sertraline, zolpidem and fentanyl, are drugs with potential to be used in cases of rape, property theft and organ theft. In this study, a 15 min...
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Irisflorentin: Advances on Resources, Metabolism, and Pharmacological Activities
Irisflorentin, a common plan-derived natural flavonoid, is one of the major bioactive constituents of plants from Iridaceae family, especially famous...