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Molecular imaging: design mechanism and bioapplications
Molecular imaging is a non-invasive method to image and analyze the concentration and activity of functional biomolecules in cells or in vivo at...
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Spatial Metabolomics Using Imaging Mass Spectrometry
Imaging mass spectrometry (IMS) of biological tissues is a valuable multiplexed molecular imaging probe that provides the spatial distribution of...
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Advances in photoacoustic imaging aided by nano contrast agents: special focus on role of lymphatic system imaging for cancer theranostics
Photoacoustic imaging (PAI) is a successful clinical imaging platform for management of cancer and other health conditions that has seen significant...
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A simple and efficient visualization of Rhodamine B-nido-carborane fluorescent labeling for tumor cell imaging
We prepared a visual Rhodamine B- nido -carborane fluorescent marker by one-pot method for tumor cell imaging. Firstly, the fat-soluble carborane was...
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In vivo fluorescence imaging: success in preclinical imaging paves the way for clinical applications
Advances in diagnostic imaging have provided unprecedented opportunities to detect diseases at early stages and with high reliability. Diagnostic...
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High-Pressure Single-Molecule Studies on Non-canonical Nucleic Acids and Their Interactions
High hydrostatic pressure affects the structure, dynamics, and the stability of biomolecular systems. Therefore, in order to describe the entire...
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Fluorescent Probes for Cysteine and Cysteine Oxidation Imaging
Cysteine is an important regulator of redox processes. Due to the nucleophilic and oxidative sensitivity, cysteine residues in proteins can be...
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Single-cell multimodal imaging uncovers energy conversion pathways in biohybrids
Microbe–semiconductor biohybrids, which integrate microbial enzymatic synthesis with the light-harvesting capabilities of inorganic semiconductors,...
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Recent advances in mass spectrometry imaging of single cells
Mass spectrometry imaging (MSI) is a sensitive, specific, label-free imaging analysis technique that can simultaneously obtain the spatial...
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Asymmetric rotaxanes as dual-modality supramolecular imaging agents for targeting cancer biomarkers
Dual-modality imaging agents featuring both a radioactive complex for positron emission tomography (PET) and a fluorophore for optical fluorescence...
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Aggregation-induced Emission Probe for Fluorescence/Photoacoustic Dual-modality Imaging and Photodynamic/Photothermal Treatment
The combination of near-infrared (NIR) fluorescence imaging (FLI) and photoacoustic imaging (PAI) can effectively compensate for each other’s...
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Crosstalk-free colloidosomes for high throughput single-molecule protein analysis
Droplet microfluidics is a powerful platform for high-throughput single-molecule protein analysis. However, the issues of coalescence and crosstalk...
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Imaging of Plant Hormones with Nanoparticle-Assisted Laser Desorption/Ionization Mass Spectrometry
Plant hormones can act in synergistic and antagonistic ways in response to biotic and abiotic stresses and during plant growth and development. Thus,...
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Silicon-RosIndolizine fluorophores with shortwave infrared absorption and emission profiles enable in vivo fluorescence imaging
In vivo fluorescence imaging in the shortwave infrared (SWIR, 1,000–1,700 nm) and extended SWIR (ESWIR, 1,700–2,700 nm) regions has tremendous...
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Metal Phosphate and Phosphonate Application for Imaging and Diagnosis
Metal phosphate and phosphonate are hybrid materials prepared from the chemical interaction between organic and inorganic material that owns the...
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Transient State (TRAST) Spectroscopy and Imaging: Exploiting the Rich Information Source of Fluorophore Dark State Transitions in Biomolecular and Cellular Studies
Dark state transitions of fluorophores are central for all forms of fluorescence-based, single-molecule and super-resolution microscopy and...
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Multiplexed in situ RNA imaging by combFISH
Multiplexed in situ RNA imaging offers new opportunities for gene expression profiling by providing high-throughput spatial information. In this...
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Oncogene-targeting nanoprobes for early imaging detection of tumor
Malignant tumors have been one of the major reasons for deaths worldwide. Timely and accurate diagnosis as well as effective intervention of tumors...
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Imaging Study of Small Molecules to G-Quadruplexes in Cells
Many guanine-rich oligonucleotides are found in the human genome, which may fold into G-quadruplex (G4) structures under physiological conditions....
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Imaging Study of Small Molecules to G-Quadruplexes in Cells
Many guanine-rich oligonucleotides are found in the human genome, which may fold into G-quadruplex (G4) structures under physiological conditions....