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Aryl C-H iodination: are there actual flavin-dependent iodinases in nature?
Flavin-dependent halogenases (FDHs) are well known to introduce carbon halide bonds (mainly C-Cl and C-Br) into natural products with the assistance...
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In silico assessment of natural products and approved drugs as potential inhibitory scaffolds targeting aminoacyl-tRNA synthetases from Plasmodium
Malaria remains the leading cause of deaths globally, despite significant advancement towards understanding its epidemiology and availability of...
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Composition and Distribution of Organic Compounds in Oil-Contaminated Peat Soils of the Mamontovskoye Field (KhMAO–Yugra)
AbstractChanges in the composition of oil compounds in a vertical section of peat soil on the territory of the Mamontovskoye oilfield (KhMAO, Western...
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Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Proteins
Green fluorescent proteins (GFPs) have lightened up almost every aspect of biological research including protein sciences. In the field of membrane...
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Inhibition of Listeria Monocytogenes HtrA Protease with Camostat, Gabexate and Nafamostat Mesylates and the Binding Mode of the Inhibitors
In many bacteria, the High Temperature requirement A (HtrA) protein functions as a chaperone and protease. HtrA is an important factor in stress...
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Modified Aluminum-Magnesium Oxide Catalysts in the Process of Ethoxylation of Higher Fatty Acid Methyl Esters
Oxyethylation leads to obtaining nonionic surfactants that are widely used in many branches of industry. The potential hydrophobic raw materials used...
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Understanding Pseudophosphatase Function Through Biochemical Interactions
Pseudophosphatases have been solidified as important signaling molecules that regulate signal transduction cascades. However, their mechanisms of...
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Study on relationships between detonation characteristics and molecular structure parameters of hydrocarbon fuels
Detonation characteristics of hydrocarbon fuels are important indexes for their safety evaluation and protection. To investigate the detonation...
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Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs
Ubiquitination plays essential roles in eukaryotic cellular processes. The effector protein CteC from Chromobacterium violaceum blocks host...
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Synthetic Studies on the Pamamycin Macrodiolides
The pamamycins are structurally intriguing 16-membered macrodiolides displaying a wide range of interesting biological activities. A comprehensive...
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Repurposing degradation pathways for modular metabolite biosynthesis in nematodes
Recent studies have revealed that Caenorhabditis elegans and other nematodes repurpose products from biochemical degradation pathways for the...
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Protein Structure Prediction and Analysis
Why it is important to know this material? Protein structure prediction is one of the hot topics of the modern computational biology. The...
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A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule
Bacterial capsules have critical roles in host-pathogen interactions. They provide a protective envelope against host recognition, leading to immune...
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Comparative Analysis of High-Viscosity Oils from the Khanty-Mansi Autonomous Okrug and the Naftalan Oil Field to Assess Their Balneological Potential
AbstractThe physicochemical properties, fractional composition, structural-group composition, molecular composition, and the content of individual...
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Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
BackgroundCost-effective production of biofuels from lignocellulose requires the fermentation of d -xylose. Many yeast species within and closely...
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Genetics and Proteomics of Polyextremophiles Existing in High Temperature
Extremophiles thrive under extreme environmental conditions, such as high/low temperatures (41–122 °C for thermophiles), where most life forms find...
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Genome-wide association study and transcriptome analysis reveal key genes affecting root growth dynamics in rapeseed
BackgroundIn terms of global demand, rapeseed is the third-largest oilseed crop after soybeans and palm, which produces vegetable oil for human...
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Expression profiling and in silico homology modeling of Inositol pentakisphosphate 2-kinase, a potential candidate gene for low phytate trait in soybean
Low phytate soybeans are desirable both from a nutritional and economic standpoint. Inositol 1, 3, 4, 5, 6-penta kis phosphate 2-kinase (IPK1),...
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Metabolic changes in response to varying whole-grain wheat and rye intake
Epidemiological studies have shown associations between whole-grain intake and lowered disease risk. A sufficient level of whole-grain intake to...
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Saturated and Aromatic Hydrocarbons Biomarkers in Crude Oil and Bitumens from Kugas 364-0 Parametric Well (Sakha (Yakutia) Republic, Russia)
AbstractThe composition and distribution of biomarkers in crude oil and dispersed organic matter of Vendian–Cambrian deposits from the Kugas 364-0...
