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Conducting polymers as sorbents of influenza viruses
Polyaniline, polypyrrole and conjugated polymers modified with silver nanoparticles have been studied as sorbents of influenza viruses from aqueous...
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A Chromatographic Strip for Rapid Semi-quantitative Detection of H5 Subtype Avian Influenza Viruses in Poultry
An immunochromatographic strip was developed for rapid semi-quantitative of the H5 subtype of avian influenza viruses (H5 AIVs) in poultry. A...
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Bottom-Up Proteomics Methods for Strain-Level Ty** and Identification of Bacteria
Timely identification of bacteria is of vital importance in many areas of public health, biotechnology, forensics, and epidemiology. Mass...
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Rapid hemagglutinin subty** of novel avian-origin influenza A(H7N9) virus using a diagnostic microarray
An epidemic of human H7N9 influenza virus infection has recently emerged in China, caused by the novel reassortant avian-origin influenza A virus...
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Dynamics and structural determinants of ligand recognition of the 5-HT6 receptor
In order to identify molecular models of the human 5-HT 6 receptor suitable for virtual screening, homology modeling and membrane-embedded molecular...
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Shikimic Acid Pathway
Of the identified biosynthetic paths, shikimic acid pathway plays a very important role in providing precursors of a large number of aromatic...
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Paramagnetic Particles and PNA Probe for Automated Separation and Electrochemical Detection of Influenza
Considerable efforts have been devoted to the development of rapid and sensitive methods allowing the detection of viral nucleic acid. We herein...
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Sialoside Arrays: New Synthetic Strategies and Applications
Sialic acid-containing carbohydrates, or sialosides, play critical roles in many biological events and in diseases, including viral and bacterial...
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Label-free microcantilever-based immunosensors for highly sensitive determination of avian influenza virus H9
We report on label-free immunosensors for the highly sensitive detection of avian influenza virus. The method makes use of the microcantilevers of an...
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Self-assembled peptide amphiphiles function as multivalent binder with increased hemagglutinin affinity
BackgroundA promising way in diagnostic and therapeutic applications is the development of peptide amphiphiles (PAs). Peptides with a palmitic acid...
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Novel algorithm for phylogenetic analysis of proteins: application to analysis of the evolution of H5N1 influenza viruses
The highly pathogenic avian influenza virus (HPAIV) A subtype H5N1 is causing threat to human health over the years. Phylogenetic analysis is an...
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Modular glycosphere assays for high-throughput functional characterization of influenza viruses
BackgroundThe ongoing global efforts to control influenza epidemics and pandemics require high-throughput technologies to detect, quantify, and...
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The first synthesis of 3-deoxyoripavine and its utilization in the preparation of 10-deoxyaporphines and cyprodime
The synthesis of 3-deoxyoripavine (7) was realized as a novel and promising intermediate towards the synthesis of the important class of dopaminergic...
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Synthesis and Biological Applications of Phosphinates and Derivatives
This review first outlines general considerations on phosphinic acids and derivatives as bioisosteric groups. The next sections present key aspects...
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Setting up a platform for plant-based influenza virus vaccine production in South Africa
BackgroundDuring a global influenza pandemic, the vaccine requirements of develo** countries can surpass their supply capabilities, if these exist...
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Simultaneous subty** and pathoty** of the 2010–2011 South Korean HPAI outbreak strain by using a diagnostic microarray
The highly pathogenic avian influenza (HPAI) subtype H5N1 virus has caused continuous outbreaks in the poultry industry with devastating economic...
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Synthesis of aryl-substituted or aryl-fused N-hydroxyethyl and N-hydroxymethypyrazole derivatives as potential ligands for the estrogen receptor
A new series of N -hydroxyethylpyrazole ( 12a – f ) and N -hydroxymethylpyrazole derivatives ( 15a – f ) were designed for their estrogenic activities, having...
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Early In Vitro Transcription Termination in Human H5 Influenza Viral RNA Synthesis
Rapid diagnostic identification of the human H5 influenza virus is a strategic cornerstone for outbreak prevention. We recently reported a method for...
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Molecular insights into the binding affinity and specificity of the hemagglutinin cleavage loop from four highly pathogenic H5N1 isolates towards the proprotein convertase furin
AbstractThe furin (FR) complex with each of four different sequences of hemagglutinin from the highly pathogenic H5N1 strains (HPH5), which were...
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Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry
BackgroundThe timely and accurate diagnosis of specific influenza virus strains is crucial to effective prophylaxis, vaccine preparation and early...
