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Mesoporous polymers: soft-template self-assembly synthesis and applications
Mesoporous polymers combine the advantages of polymer materials (abundant polar functional groups, lightweight, flexibility, and processability) and...
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Computational Protein Binding
Why it is important to know this material? The computational approach to protein binding has become a crucial methodology in drug design and...
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An in silico study to unveil potential drugs and vaccine chimera for HBV capsid assembly protein: combined molecular docking and dynamics simulation approach
Humans are a major reservoir of the hepatitis B virus (HBV), therefore promising treatment and control vaccination strategies are needed to eradicate...
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Artificial Protein Cages Assembled via Gold Coordination
Artificial protein cages made from multiple copies of a single protein can be produced such that they only assemble upon addition of a metal ion....
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Protein Cages and Nanostructures Constructed from Protein Nanobuilding Blocks
Protein cages and nanostructures are promising biocompatible medical materials, such as vaccines and drug carriers. Recent advances in designed...
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Advances in ECM Protein-Based Materials
Proteins are the main building blocks of cell structure that play a vital role in the development of cell skeletons, cell differentiation,...
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Setup and Applications of Modular Protein Expression Toolboxes (MoPET) for Mammalian Systems
The design and generation of an optimal protein expression construct is the first and essential step in the characterization of any protein of...
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Crystalline Biohybrid Materials Based on Protein Cages
Highly ordered superstructures of nanomaterials can be synthesized using protein cages as templates for the assembly of inorganic nanoparticles....
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Self-Assembly DNA-Conjugated Polymer for DNA Immobilization on Chip
DNA chips are extensively used for genome and transcriptome analyses in the post-genomic sequence era. A self-assembly technique can be applied to...
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Nucleic acid aptasensor with magnetically induced self-assembly for the detection of EpCAM glycoprotein
A “turn-on” aptasensor for label-free and cell-free EpCAM detection was constructed by employing magnetic α-Fe 2 O 3 /Fe 3 O 4 @Au nanocomposites as a matrix...
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Computational analysis of protein synthesis, diffusion, and binding in compartmental biochips
Protein complex assembly facilitates the combination of individual protein subunits into functional entities, and thus plays a crucial role in...
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Protein Structure Prediction and Analysis
Why it is important to know this material? Protein structure prediction is one of the hot topics of the modern computational biology. The...
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Cryptic enzymatic assembly of peptides armed with β-lactone warheads
Nature has evolved biosynthetic pathways to molecules possessing reactive warheads that inspired the development of many therapeutic agents,...
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Tuning the Assembly of Bispecific Antibodies by Playing on Differential Polypeptide Chain Molar Ratios
Bispecific antibodies (bsAb) represent the most promising class of therapeutics due to their multiple mode of action. Their development raised...
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Coiled-Coil Protein Origami: Design, Isolation, and Characterization
Coiled-coil protein origami (CCPO) is a rationally designed de novo protein fold, constructed by concatenating coiled-coil forming segments into a...
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Challenges of Protein-Protein Docking of the Membrane Proteins
Despite the recent advances in the determination of high-resolution membrane protein (MP) structures, the structural and functional characterization...
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Enzymology of assembly line synthesis by modular polyketide synthases
Modular polyketide synthases (PKSs) run catalytic reactions over dozens of steps in a highly orchestrated manner. To accomplish this synthetic feat,...
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Molecular Dynamics Simulation of Protein Cages
Molecular dynamics (MD) simulations enable the description of the physical movement of the system over time based on classical mechanics at various...
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Fluorescence turn-on detection of human serum albumin based on the assembly of gold nanoclusters and bromocresol green
As the most abundant protein in plasma, human serum albumin plays a vital role in physiological processes, such as maintaining blood osmotic pressure...
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An Introduction to Colloid Science and Colloidal Self-Assembly
We wrote this book for those who wish to begin the study of colloidal self-assembly. Colloids are model systems for soft matter physics and other...