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Isoflavones and Noncommunicable Diseases: Pharmacological Perspectives
Flavonoids are important natural products synthesized as secondary metabolites in various plants. These are polyphenolic compounds present in various... -
Ameliorative effect of mussel-derived ACE inhibitory peptides on spontaneous hypertension rats
PurposeThe purpose of this study was to prepare the novel mussel-derived ACE inhibitory peptides (MEPs) by enzymatic hydrolysis of Mytilus edulis ...
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Nanomedicine Applied to Inflammatory and Infectious Pulmonary Diseases
Chronic pulmonary diseases often include inflammation in the upper or lower respiratory tract causing severe/extreme discomfort. To subside... -
Carbon nanomaterials for sweat-based sensors: a review
Sweat is easily accessible from the human skin’s surface. It is secreted by the eccrine glands and contains a wealth of physiological information,...
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Differential metabolism of choline supplements in adult volunteers
BackgroundAdequate intake of choline is essential for growth and homeostasis, but its supply does often not meet requirements. Choline deficiency...
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Natural flavonoids for the amelioration of acetaminophen-induced hepatotoxicity: a systems pharmacology-based study
Natural flavonoids have been promising in protecting against liver injuries induced by acetaminophen overdose, the leading cause of drug-induced...
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Self-assembled Supramolecular Artificial Transmembrane Ion Channels: Recent Progress and Application
N atural protein channels have evolved with fantastic spatial structures, which play pivotal physiological functions in all living systems. Learning...
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Chemical Biology: Addressing New Drug Targets
Despite successes in genome research, the development of new drugs remains a challenge. The central problem is that the majority of genes and their... -
Digestion and Assimilation of Nutrients
In the human body, food is broken down in the digestive system into a form that can be easily absorbed and used as fuel. The digestive system... -
Animal Models of Renal Pathophysiology and Disease
Renal diseases remain devastating illnesses with unacceptably high rates of mortality and morbidity worldwide. Animal models are essential tools to... -
State of the Art in Integrated Biosensors for Organ-on-a-Chip Applications
Organ-on-a-chip (OoaC) is a potential emerging technology in the healthcare business based on bioengineered tissue constructions combined with... -
Genomic Variation
All humans have almost the same genome with an almost identical DNA sequence of more than 3.2 billion base pairs (i.e. 6.4 billion DNA letters). Only... -
Pharmacokinetics of Nanoparticle Systems for Pulmonary Delivery
The introduction of nanotechnology in the pharmaceutical field has incited the attention of researchers to develop nanoparticle-based formulations to... -
Aberrant GSH reductase and NOX activities concur with defective CFTR to pro-oxidative imbalance in cystic fibrosis airways
Cystic fibrosis (CF) is associated to impaired Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) channel also causing decreased glutathione...
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Curcuma longa
It is a perennial rhizomatous herb, 0.6—1 m high with a short stem and tufted leaves. It is extensively cultivated in several states of India,... -
Plasmid Vaccines and Therapeutics: From Design to Applications
In the late 1980s, Vical and collaborators discovered that the injection into tissues of unformulated plasmid encoding various proteins resulted in... -
Evolution of Transgenic Technology: From Random Transgenesis to Precise Genome Editing
New techniques in molecular biology help us for better understanding of biological processes. As biologists we resort to powerful approaches for... -
Breath Analysis as Part of Pulmonary Function Diagnostics
Modern methods of pulmonary function diagnosis include spirometry, body plethysmography and a variety of other common tests used to assess a... -