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Breath Analysis as Part of Pulmonary Function Diagnostics
Modern methods of pulmonary function diagnosis include spirometry, body plethysmography and a variety of other common tests used to assess a...
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Extracellular vesicles and COPD: foe or friend?
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease characterized by progressive airflow limitation. The complex...
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Whole-grain intake in mid-life and healthy ageing in the Danish Diet, Cancer and Health cohort
PurposeGrowing elderly populations worldwide have sparked interest in factors promoting healthy aging. Diet and other lifestyle patterns are key...
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Comparison between the Results of the Gas Chromatography–Mass Spectrometry Analysis of Solutions of the Silyl Derivatives of Dried Exhaled Breath Condensate Samples from Patients with Bronchial Asthma and COPD and Healthy Volunteers
AbstractExhaled breath condensate (EBC) as a test material in metabolomic studies continues to receive the attention of analysts. The exhaled air...
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Sample preparation strategy for the detection of steroid-like compounds using MALDI mass spectrometry imaging: pulmonary distribution of budesonide as a case study
Corticosteroids as budesonide can be effective in reducing topic inflammation processes in different organs. Therapeutic use of budesonide in...
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A roadmap to pulmonary delivery strategies for the treatment of infectious lung diseases
Pulmonary drug delivery is a highly attractive topic for the treatment of infectious lung diseases. Drug delivery via the pulmonary route offers...
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Long-term dietary fiber intake and risk of chronic obstructive pulmonary disease: a prospective cohort study of women
PurposeUntil now, only two prospective cohort studies have investigated dietary fiber intake in relation to risk of chronic obstructive pulmonary...
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Isoflavones and Noncommunicable Diseases: Pharmacological Perspectives
Flavonoids are important natural products synthesized as secondary metabolites in various plants. These are polyphenolic compounds present in various...
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Quantitative biochemical phenotypic heterogeneity of senescent macrophage at a single cell level by Synchrotron Radiation Fourier Transform Infrared Microspectroscopy
Macrophage senescence plays an important role in pathophysiological process of age-related diseases such as atherosclerosis, chronic obstructive...
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Blueberry extract improves redox balance and functional parameters in the right ventricle from rats with pulmonary arterial hypertension
PurposePulmonary arterial hypertension (PAH) is a disease characterized by increased pulmonary vascular resistance and right ventricle (RV) failure....
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Investigation of controlled salmeterol xinafoate and fluticasone propionate release from double molecular imprinted nanoparticles
Salmeterol xinafoate (SAM) and fluticasone propionate (FLU) are one of the drug combinations used together in the treatment of lung diseases such as...
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Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice
ObjectiveSmoking was a major risk factor for chronic obstructive pulmonary disease (COPD). This study plan to explore the mechanism of Polyphyllin B...
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Elucidating the mechanistic sensing capability of novel tetragonal graphene quantum dot towards tobacco alkaloids: a DFT study
Smoking is the g`reatest preventable cause of mortality all over the world as it causes lung cancer, vascular disease, peptic ulcers, coronary heart...
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Potential Benefits of Bioactive Functional Components of Citrus Fruits for Health Promotion and Disease Prevention
As accumulating evidence ties dietary ingredients to disease therapy and prevention, the notion that food can be nutritionally beneficial and...
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Integrative Analyses of Bulk and Single-Cell RNA Seq Identified the Shared Genes in Acute Respiratory Distress Syndrome and Rheumatoid Arthritis
Acute respiratory distress syndrome (ARDS), a progressive status of acute lung injury (ALI), is primarily caused by an immune-mediated inflammatory...
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A PVDF-based colorimetric sensor array for noninvasive detection of multiple disease-related volatile organic compounds
Detection of human-generated volatile organic compounds (VOCs) is a new pathway for assessing health. Herein, a polyvinylidene fluoride (PVDF)-based...
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Targeted siRNA delivery to lung epithelia reduces airway inflammation in a mouse model of allergic asthma
Asthma is a chronic inflammatory disease triggered by allergic reactions in the bronchia. These reactions lead to swelling of mucous membranes,...
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Cardiac Valves
After the first transcatheter aortic valve replacement became a reality in humans in 2002, there has been an explosion in the development of...
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CircDiaph3 influences PASMC apoptosis by regulating PI3K/AKT/mTOR pathway through IGF1R
The pathogenesis of pulmonary hypertension has not been elucidated. We investigated the role of a circular ribonucleic acid, circDiaph3, in the...
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Clearing the Path: Exploring Apoptotic Cell Clearance in Inflammatory and Autoimmune Disorders for Therapeutic Advancements
AbstractInflammatory and autoimmune disorders, characterized by dysregulated immune responses leading to tissue damage and chronic inflammation,...
