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Combinatorial use of environmental stresses and genetic engineering to increase ethanol titres in cyanobacteria
Current industrial bioethanol production by yeast through fermentation generates carbon dioxide. Carbon neutral bioethanol production by...
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High-yield β-alanine production from glucose and acetate in Escherichia coli
β -Alanine is a versatile amino acid with wide-range industrial applications, but its production from glucose has been limited by a low yield. This...
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Oxidoreduction potential controlling for increasing the fermentability of enzymatically hydrolyzed steam-exploded corn stover for butanol production
BackgroundLignocellulosic biomass is recognized as an effective potential substrate for biobutanol production. Though many pretreatment and...
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Microbial Production of Pyruvic, Lactic, and 3-Hydroxy Propionic Acid from Renewable Resources
Microbial production of value-added chemicals is important for establishing a sustainable society. Owing to increasing environmental concerns related...
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Escherichia coli Cell Factory for Synthesis of Biomolecules
In the past century, Escherichia coli (E. coli) has risen to be among the most researched creatures on earth. E. coli is a preferred platform host...
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Map** competitive pathways to terpenoid biosynthesis in Synechocystis sp. PCC 6803 using an antisense RNA synthetic tool
BackgroundSynechocystis sp. PCC 6803 utilizes pyruvate and glyceraldehyde 3-phosphate via the methylerythritol 4-phosphate (MEP) pathway for the...
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An engineered non-oxidative glycolytic bypass based on Calvin-cycle enzymes enables anaerobic co-fermentation of glucose and sorbitol by Saccharomyces cerevisiae
BackgroundSaccharomyces cerevisiae is intensively used for industrial ethanol production. Its native fermentation pathway enables a maximum product...
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Improved succinic acid production through the reconstruction of methanol dissimilation in Escherichia coli
Synthetic biology has boosted the rapid development on using non-methylotrophy as chassis for value added chemicals production from one-carbon...
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High throughput 13C-metabolic flux analysis of 3-hydroxypropionic acid producing Pichia pastoris reveals limited availability of acetyl-CoA and ATP due to tight control of the glycolytic flux
BackgroundProduction of 3-hydroxypropionic acid (3-HP) through the malonyl-CoA pathway has yielded promising results in Pichia pastoris ( Komagataella...
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Increasing cellular fitness and product yields in Pseudomonas putida through an engineered phosphoketolase shunt
BackgroundPseudomonas putida has received increasing interest as a cell factory due to its remarkable features such as fast growth, a versatile and...
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Metabolic Engineering and Synthetic Biology in Biohydrogen Production
Hydrogen is a well-accepted clean fuel which is gradually replacing the conventional fossil fuels, and biohydrogen is a net zero fuel produced via...
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Recent advances in bio-based production of top platform chemical, succinic acid: an alternative to conventional chemistry
Succinic acid (SA) is one of the top platform chemicals with huge applications in diverse sectors. The presence of two carboxylic acid groups on...
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Unraveling the mechanism of raffinose utilization in Ligilactobacillus salivarius Ren by transcriptomic analysis
In the gastrointestinal tract, some dietary carbohydrates, such as xylose, raffinose and arabinose, are able to stimulate the growth of Lactobacillus ...
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Water-Soluble Vitamins
Water-soluble vitamins are a group of essential dietary components required in small quantities that are defined by their polar nature and are hence...
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Inhibitory Mechanisms of Plant Volatile 1-Octanol on the Germination of Aspergillus Flavus Spores
Biogenic volatile organic compounds have promising applications in controlling fungal spoilage of postharvest agro-products and perishable foods. In...
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‘Dark’ CO2 fixation in succinate fermentations enabled by direct CO2 delivery via hollow fiber membrane carbonation
Anaerobic succinate fermentations can achieve high-titer, high-yield performance while fixing CO 2 through the reductive branch of the tricarboxylic...
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Carbon dioxide fixation via production of succinic acid from glycerol in engineered Saccharomyces cerevisiae
BackgroundThe microbial production of succinic acid (SA) from renewable carbon sources via the reverse TCA (rTCA) pathway is a process potentially...
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GATA-type transcriptional factor SpGAT1 interacts with SpMIG1 and promotes lipid accumulation in the oleaginous yeast \(Saitozyma \ podzolica\) zwy-2-3
BackgroundIn oleaginous yeast, nitrogen limitation is a critical parameter for lipid synthesis. GATA-family transcriptional factor GAT1, a member of...
