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Alkaloids in Diet
Food is one of the three basic requirements of mankind, supplying six kinds of nutrients including water, carbohydrate, protein, lipid, vitamins, and...
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Variation in Leaf-Surface and Leaf-Tissue Secondary Metabolites: Pyrrolizidine Alkaloids
Pyrrolizidine alkaloids (PAs) represent a class of typical SMs, which are constitutively formed in plants containing them and mediating...
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Determination and Chemical Profiling of Toxic Pyrrolizidine Alkaloids in Botanical Samples with UPLC–Q-TOFMS
Pyrrolizidine alkaloids (PAs) and their N -oxides (PANOs) can cause liver toxicity and genotoxicity in humans and animals, necessitating the...
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Discriminant analysis of pyrrolizidine alkaloid contamination in bee pollen based on near-infrared data from lab-stationary and portable spectrometers
Bee pollen may be contaminated with pyrrolizidine alkaloids (PAs) and their N -oxides (PANOs), which are mainly detected by liquid chromatography...
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Development of UPLC-Q-TOF-MS Coupled with Cation-exchange Solid-phase Extraction Method for the Determination of Ten Pyrrolizidine Alkaloids in Herbal Medicines
Pyrrolizidine alkaloids are secondary metabolites of plants and can cause significant hepatotoxicity in humans. In this study, a fast and simple...
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Extraction of bioactive compounds from Senecio brasiliensis using emergent technologies
Several plant species synthesize biologically active secondary metabolites. Pyrrolizidine alkaloids are a large group of biotoxins produced by...
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Development of a sensitive analytical method for determining 44 pyrrolizidine alkaloids in teas and herbal teas via LC-ESI-MS/MS
Pyrrolizidine alkaloids (PA) and PA- N -oxides (PANO) are a large group of secondary plant metabolites comprising more than 660 compounds. Exhibiting...
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Insect Chemical Defense
Research on the defensive chemistry of insects during the last decade is reviewed, with special emphasis on non-volatile compounds. The isolation and...
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The Chemistry and Chemical Ecology of Lepidopterans as Investigated in Brazil
The interdisciplinary field of Chemical Ecology in Brazil is currently composed of groups that emerged through the pioneering studies of Keith...
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Development, validation, and application of a multi-method for the determination of mycotoxins, plant growth regulators, tropane alkaloids, and pesticides in cereals by two-dimensional liquid chromatography tandem mass spectrometry
Mycotoxins and pesticides regularly co-occur in agricultural products worldwide. Thus, humans can be exposed to both toxic contaminants and...
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Evolution of the Angiosperms and Co-evolution of Secondary Metabolites, Especially of Alkaloids
Plants produce a wide variety of secondary metabolites (PSM) for protection against herbivores, microorganisms, and competing plants. PSM also...
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Evolution of the Angiosperms and Co-evolution of Secondary Metabolites, Especially of Alkaloids
Plants produce a wide variety of secondary metabolites (PSM) for protection against herbivores, microorganisms, and competing plants. PSM also...
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Modern Approaches to the Extraction and Preconcentration of Biologically Active Compounds from Plant Samples by Microextraction Methods for Their Determination by Chromatography–Mass Spectrometry
AbstractThe review considers the main trends in actively develo** methods of solid-phase and liquid–liquid microextraction for the extraction,...
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Regio- and Stereoselective 1,3-dipolar Cycloaddition of Azomethine Ylides Based on Isatins and (thia)proline to 3-nitro-2-(trifluoro(trichloro)methyl)-2H-chromenes: Synthesis and Cytotoxic Activity of 6-(trihalomethyl)-spiro[chromeno(thia)pyrrolizidine-11,3'-indolin]-2'-ones
A regio- and stereoselective method for the synthesis of (trifluoro(trichloro)methyl)-substituted spiro[chromeno(thia)pyrrolizidineoxindoles] in...
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CRISPR-Cas-Mediated Optimization of Plant-Derived Natural Products of Biomedical Significance
Medicinal plants have been used since time immemorial to heal mankind on all three tiers, namely, spiritual health, mental health, and physical...
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Catalyst-free rapid crystallization-induced stereoselective three-component [3 + 2] cycloaddition to polycyclic spirooxindoles under microwave irradiation
[3 + 2] Cycloaddition reactions are powerful tools to build alkaloid skeleton compounds. While maleimides are common dipolarophiles, the successful...
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Bioactive Compounds from Food and Its By-products: Current Applications and Future Perspectives
Foods are important for the supply of essential nutrients to the body, but they can also be sources of bioactive molecules, such as phenolic...
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Seed Lipids of Onosma Species from Various Climate Zones
Fourteen wild (W) and cultivated (C) seed samples from nine Onosma species were collected in various climate zones and were analyzed for contents of...
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New Trends from Plant Secondary Metabolism in the Pharmaceutical Industry
Plants constitute nowadays an important source for the discovery of new products of medicinal value for drug development, food additives, and...
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Discovery of Natural Veterinary Herbal Medicine Products in Commercial Cow Milk by Using Nontargeted Profiling on LC–ESI–TOF Platform
For centuries, herbal medicines have been used to treat humans and animals. Veterinary medicines are well-regulated; inspectors monitor milk and...
