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Monitoring of Cell Membrane Microenvironment Based on DNA Nanodevices
The cell membrane is a critical barrier for cellular homeostasis, integral to signaling and intercellular communication, and vital for understanding...
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Environmental and intercellular Pb2+ ions determination based on encapsulated DNAzyme in nanoscale metal-organic frameworks
With the merits of low cost, simple synthesis procedure, and high affinity for metal ions, deoxyribozyme (DNAzyme) have played important roles in...
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Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis. Apoptotic bodies (ApoBDs) are a form of extracellular...
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The Functional Study of Response Regulator ArlR Mutants in Staphylococcus Aureus
Staphylococcus aureus is a major cause of hospital-associated infections worldwide. The organism’s ability to form biofilms has led to resistance...
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An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironments
Tumors desmoplastic microenvironments are characterized by abundant stromal cells and extracellular matrix (ECM) deposition. Cancer-associated...
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Perilla oil and α-linolenic acid ameliorated thrombosis in rats induced by collagen and epinephrine
Perilla frutescens is an annual herbaceous plant widely cultivated for oil production in China, Japan, and Korea. In this study, we investigated the...
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Shuttling Homeoproteins and Their Biological Significance
The transfer of homeoprotein Homeoproteins transcription factorsTranscription factors (TFs) is at the origin of the discovery of...
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Competitive protein recruitment in artificial cells
Living cells can modulate their response to environmental cues by changing their sensitivities for molecular signals. Artificial cells are promising...
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Quantitative biochemical phenotypic heterogeneity of senescent macrophage at a single cell level by Synchrotron Radiation Fourier Transform Infrared Microspectroscopy
Macrophage senescence plays an important role in pathophysiological process of age-related diseases such as atherosclerosis, chronic obstructive...
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Identification of peroxiredoxin II and its related molecules as potential biomarkers of dermal mesenchymal stem cell homing using network analysis
In this study, we performed RNA sequencing of Prx II +/+ and Prx II −/− dermal mesenchymal stem cells (DMSCs) to identify differentially expressed...
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Co-culturing experiments reveal the uptake of myo-inositol phosphate synthase (EC 5.5.1.4) in an inositol auxotroph of Saccharomyces cerevisiae
BackgroundMyo-Inositol Phosphate Synthase (MIP) catalyzes the conversion of glucose 6- phosphate into inositol phosphate, an essential nutrient and...
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Enhancing lettuce yield via Cu/Fe-layered double hydroxide nanoparticles spraying
Layered double hydroxides (LDHs) have been widely used in the field of plant engineering, such as DNA/RNA transformation and enhancing plant disease...
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Tumor-derived small extracellular vesicles: potential roles and mechanism in glioma
Small extracellular vesicles (SEVs) are extracellular vesicles containing DNA, RNA, and proteins and are involved in intercellular communication and...
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Dominoes with interlocking consequences triggered by zinc: involvement of microelement-stimulated MSC-derived exosomes in senile osteogenesis and osteoclast dialogue
As societal aging intensifies, senile osteoporosis has become a global public health concern. Bone microdamage is mainly caused by processes such as...
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Anti-biofilm effects of sinomenine against Staphylococcus aureus
Staphylococcus aureus is a gram-positive foodborne pathogen capable of forming strong biofilms. This study identified that anti-biofilm natural...
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Recent advances in the use of extracellular vesicles from adipose-derived stem cells for regenerative medical therapeutics
Adipose-derived stem cells (ADSCs) are a subset of mesenchymal stem cells (MSCs) isolated from adipose tissue. They possess remarkable properties,...
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Cudrania tricuspidata leaf extracts and its components, chlorogenic acid, kaempferol, and quercetin, increase claudin 1 expression in human keratinocytes, enhancing intercellular tight junction capacity
Dysfunction of tight junctions and their components can cause diverse skin diseases. Here, we investigated the expression of claudin 1, a major tight...
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Recent Progress in the Development of Droplet-based Microfluidic Technologies for Phenotypic Screening using Cell-cell Interactions
Specific cell-cell interactions enable the complex metabolic tasks associated with natural microbial communities and facilitates their improved...
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Exosomal miR-146a-5p derived from human umbilical cord mesenchymal stem cells can alleviate antiphospholipid antibody-induced trophoblast injury and placental dysfunction by regulating the TRAF6/NF-κB axis
Exosomes originating from human umbilical cord mesenchymal stem cells (hucMSC-exos) have become a novel strategy for treating various diseases owing...
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Biotransformation to synthesize the methylated derivatives of baicalein using engineered Escherichia coli
Oroxylin A and negletein are flavonoid compounds existing in plants, with excellent pharmacological activities such as anti-inflammatory,...
