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A TMVP1-modified near-infrared nanoprobe: molecular imaging for tumor metastasis in sentinel lymph node and targeted enhanced photothermal therapy
BackgroundTMVP1 is a novel tumor targeting polypeptide screened by our laboratory with a core sequence of five amino acids LARGR. It specially binds...
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Manganese-derived biomaterials for tumor diagnosis and therapy
Manganese (Mn) is widely recognized owing to its low cost, non-toxic nature, and versatile oxidation states, leading to the emergence of various...
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Boosting the sonodynamic performance of CoBiMn-layered double hydroxide nanoparticles via tumor microenvironment regulation for ultrasound imaging-guided sonodynamic therapy
Sonodynamic therapy (SDT), a promising strategy for cancer treatment with the ability for deep tissue penetration, has received widespread attention...
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Near infrared II excitation nanoplatform for photothermal/chemodynamic/antibiotic synergistic therapy combating bacterial biofilm infections
Drug-resistant bacterial biofilm infections (BBIs) are refractory to elimination. Near-infrared-II photothermal therapy (NIR-II PTT) and chemodynamic...
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NIR/pH-triggered aptamer-functionalized DNA origami nanovehicle for imaging-guided chemo-phototherapy
Targeted chemo-phototherapy has received widespread attention in cancer treatment for its advantages in reducing the side effects of...
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Melanin-like nanoparticles: advances in surface modification and tumour photothermal therapy
Currently, tumor treatments are characterized by intelligence, diversity and personalization, but the therapeutic reagents used are often limited in...
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Carbon dots-mediated synthesis of gold nanodendrites with extended absorption into NIR-II window for in vivo photothermal therapy
BackgroundPhotothermal therapy (PTT) in the second near-infrared (NIR-II) window has attracted extensive attention due to the benefits in high...
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Low-dose X-ray enhanced tumor accumulation of theranostic nanoparticles for high-performance bimodal imaging-guided photothermal therapy
BackgroundTheranostic nanoparticles (NPs) have achieved rapid development owing to their capacity for personalized multimodal diagnostic imaging and...
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Thrombus-targeted nano-agents for NIR-II diagnostic fluorescence imaging-guided flap thromboembolism multi-model therapy
In oral and maxillofacial surgery, flap repair is essential to the quality of postoperative life. Still, thrombosis is fatal for the survival of the...
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Biomimetic nanoprobe-augmented triple therapy with photothermal, sonodynamic and checkpoint blockade inhibits tumor growth and metastasis
BackgroundComprehensive antitumor therapy through integrated multimodal means has drawn increasing attention owing to its high efficiency and...
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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions of Cu2−xS cores with red emitting carbon dots
This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities, in addition...
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Photoacoustic imaging-guided chemo-photothermal combinational therapy based on emissive Pt(II) metallacycle-loaded biomimic melanin dots
Pt(II)-based metallacycles, as an important family of supramolecular coordination complexes (SCCs), have exhibited excellent antitumor activity at...
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Fabrication of a smart drug delivery system based on hollow Ag2S@mSiO2 nanoparticles for fluorescence-guided synergistic photothermal chemotherapy
A novel near-infrared (NIR) light-triggered smart nanoplatform has been developed for cancer targeting and imaging-guided combined photothermal-chemo...
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Novel multifunctional theranostic nanoagents based on Ho3+ for CT/MRI dual-modality imaging-guided photothermal therapy
Because of the intrinsic defects of traditional treatment of cancer, it is quite needed to construct novel theranostic nanoagents that can not only...
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Aggregation-induced T1/T2 contrast enhancement for magnetic resonance imaging-guided intraoperative surgery
Magnetic resonance imaging (MRI) plays an important role in precision medicine that is hampered by the lack of contrast agents with high efficiency...
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A sulfur-substituted hemicyanine for cancer photothermal therapy without influence of intracellular viscosity
Although photothermal therapy (PTT) has emerged as an appealing strategy for cancer treatment, the development of photothermal agents capable of...
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Nectin-4-targeted immunoSPECT/CT imaging and photothermal therapy of triple-negative breast cancer
BackgroundTriple-negative breast cancer (TNBC) is more prone to distant metastasis and visceral recurrence in comparison to other breast cancer...
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NIR Dye-Conjugated Maltodextrin for Photothermal Therapy of Cancer
Photothermal therapy (PTT) is one of recently emerging anticancer treatment modalities that involve the use of laser and photosensitizers. To fully...
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Image-guided cancer surgery: a narrative review on imaging modalities and emerging nanotechnology strategies
Surgical resection is the cornerstone of solid tumour treatment. Current techniques for evaluating margin statuses, such as frozen section, imprint...
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Designing highly stable ferrous selenide-black phosphorus nanosheets heteronanostructure via P-Se bond for MRI-guided photothermal therapy
BackgroundThe design of stable and biocompatible black phosphorus-based theranostic agents with high photothermal conversion efficiency and clear...
