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Plant Platforms for Efficient Heterologous Protein Production
Production of recombinant proteins is primarily established in cultures of mammalian, insect and bacterial cells. Concurrently, concept of using...
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Drug Delivery to Diseases Caused by E. coli Infection
The Escherichia coli are one of the most common facultative anaerobe in the intestinal tract of humans and many other endothermic species. Mostly,...
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Aptamers for the Diagnosis of Infectious Diseases
Nowadays, infectious diseases have been considered as life-threatening concerns worldwide. Traditional methods based on clinical features and...
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Isomorphic Fluorescent Nucleoside Analogs
Characterized by their high structural similarity to their native counterparts, yet endowed with useful photophysical features, isomorphic...
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Isomorphic Fluorescent Nucleoside Analogs
Characterized by their high structural similarity to their native counterparts, yet endowed with useful photophysical features, isomorphic...
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An Overview on Chitosan-Based Adjuvant/Vaccine Delivery Systems
Vaccination is a highly effective and safe method in preventing life-threatening infections in both human and animals. It is based on the principle...
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Tips and Tools to Understand Direct Membrane Translocation of siRNA-Loaded WRAP-Based Nanoparticles
Cell-penetrating peptide (CPP)-based approaches are excellent method for delivering cell-impermeable compounds/therapeutics such as proteins,...
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A Multi-epitope Vaccine Candidate Against Bolivian Hemorrhagic fever Caused by Machupo Virus
Bolivian hemorrhagic fever (BHF) caused by Machupo virus (MACV) is a New World arenavirus having a reported mortality rate of 25–35%. The BHF starts...
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Promising Microalgae for Nutraceutical and Food Applications: Solution for Global Food Problems
Microalgae offer a sustainable solution to food security and nutrition by producing a varied collection of high-value bioactive compounds, such as,...
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Design of a novel multi-epitope vaccine against Marburg virus using immunoinformatics studies
Marburg virus (MARV) is a highly contagious and virulent agent belonging to Filoviridae family. MARV causes severe hemorrhagic fever in humans and...
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Single-sEV profiling identifies the TACSTD2 + sEV subpopulation as a factor of tumor susceptibility in the elderly
BackgroundAging is a very complex physiological phenomenon, and sEVs are involved in the regulation of this mechanism. Serum samples from healthy...
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Whole-Cell Vaccine Preparation: Options and Perspectives
Vaccines are biological preparations to elicit a specific immune response in individuals against the targetted microorganisms. The use of vaccines...
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Recent Developments in the Treatment of Bacterial Urinary Tract Infections
Urinary tract infections (UTIs) are one of the most common infectious diseases among humans and account for over one million hospitalizations and...
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Protein Delivery and Mimicry
The multiple examples of the strategiesConjugation of the use of CPPs to shuttle the proteinsComplexation and protein mimicsProtein mimic and their...
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Membrane phase separation drives responsive assembly of receptor signaling domains
Plasma membrane heterogeneity has been tied to a litany of cellular functions and is often explained by analogy to membrane phase separation;...
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Evaluation of the Role of Probiotics As a New Strategy to Eliminate Microbial Toxins: a Review
Probiotics are living microorganisms that have favorable effects on human and animal health. The most usual types of microorganisms recruited as...
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Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats
BackgroundDiabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes and the main cause of non-traumatic amputation,...
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In Silico Design of CT26 Polytope and its Surface Display by ClearColi™-Derived Outer Membrane Vesicles as a Cancer Vaccine Candidate Against Colon Carcinoma
Simultaneous targeting of several mutations can be useful in colorectal cancer (CRC) due to its heterogeneity and presence of somatic mutations. As...
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Seed-Based System for Cost-Effective Production of Vaccine Against Chronic Respiratory Disease in Chickens
The production of vaccines in plant cells, termed plant-made pharmaceuticals or molecular farming, is a promising technology for scalable production....
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Role of Supramolecules in Vaccine Development
Biological substance(s) which generate immunity against a particular disease are called vaccines. They diminish the risks of getting a disease by...