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Downstream Processing in Marine Biotechnology
Downstream processing is one of the most underestimated steps in bioprocesses and this is not only the case in marine biotechnology. However, it...
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Asymmetric Total Synthesis of Complex Marine Natural Products
Among nature's ecosystems, the marine environment has been an extremely rich source of structurally complex and biologically active molecules. This...
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Technical Application of Biological Principles in Asymmetric Catalysis
The production of enantiopure compounds is becoming increasingly important to the chemical and biotechnological industries. Bioorganic...
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Enzyme-Catalyzed Regio- and Enantioselective Ketone Reductions
In this chapter, examples are given of the application of highly reactive prochiral ketones as substrates for enzymatic reductions....
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Aquaculture of “Non-Food Organisms” for Natural Substance Production
Marine invertebrates are already sources of commercially important secondary metabolites and may become even more so as knowledge on marine...
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Biochemistry and General Genetics of Nonribosomal Peptide Synthetases in Fungi
Peptides like penicillin or cyclosporin are nonribosomally synthesised by large multifunctional enzymes. Peptide synthetase genes are coexpressed...
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Compartmentalization and Transport in β-Lactam Antibiotics Biosynthesis
Classical strain improvement of β-lactam producing organisms by random mutagenesis has been a powerful tool during the last century. Current insights...
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Screening for New Metabolites from Marine Microorganisms
This article gives an overview of current analysis techniques for the screening and the activity analysis of metabolites from marine...
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Seafood Allergy: Lessons from Clinical Symptoms, Immunological Mechanisms and Molecular Biology
Food allergy consists of a wide range of disorders that result from adverse immune responses to dietary antigens. Manifestations of allergic...
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Marine Enzymes
Marine enzyme biotechnology can offer novel biocatalysts with properties like high salt tolerance, hyperthermostability, barophilicity, cold...
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Regulation of Penicillin Biosynthesis in Filamentous Fungi
The β-lactam antibiotic penicillin is one of the mainly used antibiotics for the therapy of infectious diseases. It is produced as end product by...
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Extraction of Primary and Secondary Metabolites
Several new methods besides the usual organic solvent extraction have been developed over the last few years for the extraction of primary and...
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Industrial Enzymatic Production of Cephalosporin-Based β-Lactams
Cephalosporins are chemically closely related to penicillins both work by inhibiting the cell wall synthesis of bacteria. The first generation...
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Enhancing monolignol ferulate conjugate levels in poplar lignin via OsFMT1
BackgroundThe phenolic polymer lignin is one of the primary chemical constituents of the plant secondary cell wall. Due to the inherent plasticity of...
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Green Extraction of Anthocyanins from Prunus domestica Using Natural Deep Eutectic Solvents: Anti-sickling Properties and Phenolic Impact Assessment
Natural Deep Eutectic Solvents (NADESs) are a form of green solvents used to extract phenolic compounds and are considered a more environmentally...
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Propionate production by Bacteroidia gut bacteria and its dependence on substrate concentrations differs among species
BackgroundPropionate is a food preservative and platform chemical, but no biological process competes with current petrochemical production routes...
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Optimization of biotransformation processes of Camarosporium laburnicola to improve production yields of potent telomerase activators
BackgroundTelomerase activators are promising agents for the healthy aging process and the treatment/prevention of short telomere-related and...
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Emerging methylation-based approaches in microbiome engineering
Bacterial epigenetics, particularly through DNA methylation, exerts significant influence over various biological processes such as DNA replication,...
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Map** a sustainable approach: biosynthesis of lactobacilli-silver nanocomposites using whey-based medium for antimicrobial and bioactivity applications
This study explores a sustainable approach for synthesizing silver nanocomposites (AgNCs) with enhanced antimicrobial and bioactivity using safe Lactobacillus...
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Production of succinate with two CO2 fixation reactions from fatty acids in Cupriavidus necator H16
BackgroundBiotransformation of CO 2 into high-value-added carbon-based products is a promising process for reducing greenhouse gas emissions. To...
