Search
Search Results
-
Tremendous Fidelity of Vitamin D3 in Age-related Neurological Disorders
Vitamin D3 (VD) is a secosteroid hormone and shows a pleiotropic effect in brain-related disorders where it regulates redox imbalance, inflammation,...
-
Vitamin D3 improves spatial memory and modulates cytokine levels in aged rats
Vitamin D3 deficiency is associated with an increased risk of dementia. An association between vitamin D3 deficiency and subjective cognitive...
-
The Effect of Vitamin D3 on Neutrophil Extracellular Trap Formation in High-Glucose Conditions
NETosis, i.e ., the formation of neutrophil extracellular traps (NET), and neutrophil autophagy are important elements in the pathogenesis and the...
-
Cardioprotective effect of vitamin D3 on cisplatin-induced cardiotoxicity in male mice: role of oxidative stress
Cisplatin (CP) is a chemotherapy drug used in a broad spectrum of cancer. The current study investigated the protective effect of vitamin D3 (vit-D3)...
-
AMPK-mediated autophagy is involved in the protective effect of canagliflozin in the vitamin D3 plus nicotine calcification model in rats
Vascular calcification (VC) is a major risk factor for cardiovascular events. A mutual interplay between inflammation, oxidative stress, apoptosis,...
-
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis
PurposeWe aimed to evaluate whether pulmonary fibrosis occurs in type 2 diabetes rat models and whether VD3 can prevent it by inhibiting pyroptosis.
...
-
The influence of vitamin D supplementation on the expression of mediators of inflammation in knee osteoarthritis
This trial aimed to determine the possible therapeutic and immunomodulatory effects of vitamin D3 in patients with knee OA. In this open-label...
-
Vitamin D3 Supplement Attenuates Blood–Brain Barrier Disruption and Cognitive Impairments in a Rat Model of Traumatic Brain Injury
This study was designed to study the effects of vitamin D3 supplementation on the cognitive dysfunction and neurological function of traumatic brain...
-
Vitamin D3 affects browning of white adipocytes by regulating autophagy via PI3K/Akt/mTOR/p53 signaling in vitro and in vivo
Promoting brown fat-like phenotype in white adipose tissue has been a promising strategy for the treatment of obesity. Vitamin D3 (VD3) has been...
-
Effect of Vitamin D3 in Composition of Original Rectal Suppositories on Parameter of Protein Oxidative Modification in Large Intestine in Experimental Ulcerative Colitis
The effect of vitamin D3 in the composition of original rectal suppositories on the content of products of oxidative modification of proteins in...
-
Emerging perspectives: unraveling the anticancer potential of vitamin D3
Vitamin D 3 , a fat-soluble vitamin known for its critical function in calcium homeostasis and bone health, is gaining interest for its anticancer...
-
Treatment with 1,25-Dihydroxyvitamin D3 Delays Choroid Plexus Infiltration and BCSFB Injury in MRL/lpr Mice Coinciding with Activation of the PPARγ/NF-κB/TNF-α Pathway and Suppression of TGF-β/Smad Signaling
Neuropsychiatric systemic lupus erythematosus (NPSLE) is a serious complication of systemic lupus erythematosus (SLE) involving the nervous system...
-
The effects of vitamin D3 supplementation on TGF-β and IL-17 serum levels in migraineurs: post hoc analysis of a randomized clinical trial
BackgroundAlthough the exact mechanism involved in migraine pathogenesis remained uncertain, and different researches have been developed to address...
-
Serum Vitamin D As a Biomarker in Diabetic: Applications and Associations with Retinopathy
Vitamin D is a multifunctional hormone with multiple biological functions including regulation of endothelial function, angiogenesis, antioxidant and...
-
Vitamin D Presented In Vitro Immunomodulatory Property on T Lymphocyte-Related Cytokines in Systemic Lupus Erythematosus
Inflammatory T lymphocyte cytokines contribute to tissue damage in SLE patients. Vitamin D (Vit D) has a well-established immunomodulatory action,...
-
Neuroinflammation in Alzheimer’s disease: potential beneficial effects of vitamin D
Alzheimer’s disease (AD) is the most common cause of dementia. In recent years, several studies have robustly shown that neuroinflammation plays a...
-
Vitamin D ameliorates age-induced nonalcoholic fatty liver disease by increasing the mitochondrial contact site and cristae organizing system (MICOS) 60 level
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease. Despite intensive research, considerable information on NAFLD development...
-
1α,25-Dihydroxyvitamin D3 (VD3) Shows a Neuroprotective Action Against Rotenone Toxicity on PC12 Cells: An In Vitro Model of Parkinson’s Disease
Parkinson’s disease (PD) is characterized by dopaminergic cell loss in the substantia nigra, and PD brains show neuroinflammation, oxidative stress,...
-
The Role of Vitamin D As a Biomarker in Trauma
Vitamin D is a collective term for two main forms of hormonal sterols that form a shared active metabolite, calcitriol. While it is essential for...
-
Co-administration of probiotics and vitamin D reduced disease severity and complications in patients with Parkinson’s disease: a randomized controlled clinical trial
RationaleProbiotics have beneficial effects on the nervous system by modulating the gut-brain axis. Additionally, vitamin D supplementation presents...
