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The in vitro dynamics of pseudo-vascular network formation
Background/ObjectivesPseudo-vascular network formation in vitro is considered a key characteristic of vasculogenic mimicry. While many cancer cell...
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VascuConNet: an enhanced connectivity network for vascular segmentation
Medical image segmentation commonly involves diverse tissue types and structures, including tasks such as blood vessel segmentation and nerve fiber...
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Vascular dysfunction in sporadic bvFTD: white matter hyperintensity and peripheral vascular biomarkers
BackgroundVascular dysfunction was recently reported to be involved in the pathophysiological process of neurodegenerative diseases, but its role in...
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Enhancer promoter interactome and Mendelian randomization identify network of druggable vascular genes in coronary artery disease
Coronary artery disease (CAD) is a multifactorial disorder, which is partly heritable. Herein, we implemented a map** of CAD-associated candidate...
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Coalescent angiogenesis—evidence for a novel concept of vascular network maturation
Angiogenesis describes the formation of new blood vessels from pre-existing vascular structures. While the most studied mode of angiogenesis is...
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Pulmonary Vascular Diseases
Pulmonary vascular diseases or pulmonary vasculopathies represent diseases of pulmonary vasculature that are associated with altered pulmonary...
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Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels
Vascular mimicry has been thoroughly investigated in tumor angiogenesis. In this study, we demonstrate for the first time that a process closely...
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Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation
Brain vascular integrity is critical for brain health, and its disruption is implicated in many brain pathologies, including psychiatric disorders....
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Risk assessment of retinal vascular occlusion after COVID-19 vaccination
Coronavirus disease 2019 (COVID-19) vaccines are associated with several ocular manifestations. Emerging evidence has been reported; however, the...
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Vascular network expansion, integrity of blood–brain interfaces, and cerebrospinal fluid cytokine concentration during postnatal development in the normal and jaundiced rat
BackgroundSevere neonatal jaundice resulting from elevated levels of unconjugated bilirubin in the blood induces dramatic neurological impairment....
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Vascular calcification: from the perspective of crosstalk
Vascular calcification (VC) is highly correlated with cardiovascular disease morbidity and mortality, but anti-VC treatment remains an area to be...
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Application of fluorescence micro-optical sectioning tomography in the cerebrovasculature and applicable vascular labeling methods
Fluorescence micro-optical sectioning tomography (fMOST) is a three-dimensional (3d) imaging method at the mesoscopic level. The whole-brain of mice...
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Functional abnormalities of the cerebellum in vascular mild cognitive impairment
ObjectivesThe alterations in cerebellar activity that occur in vascular mild cognitive impairment remain largely unexplored. This study aimed to...
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Advanced Computational Methods to Evaluate Vascular Heterogeneity in Tumor Tissue Based on Single Plane Illumination Microscopy
During tumor growth, the complex composition of vasculature is prone to dynamic changes due to mechanic and biochemical challenges. Perivascular...
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Cuproptosis and copper deficiency in ischemic vascular injury and repair
Ischemic vascular diseases are on the rise globally, including ischemic heart diseases, ischemic cerebrovascular diseases, and ischemic peripheral...
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GM-CSF Promotes the Development of Dysfunctional Vascular Networks in Moyamoya Disease
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease with the development of a network of abnormal vessels. Immune inflammation is...
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Vascular Endothelium
The endothelium is strategically located at the interface between the blood flow and the vascular smooth muscle and other components of the vessel...
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Explainable artificial intelligence for the automated assessment of the retinal vascular tortuosity
AbstractRetinal vascular tortuosity is an excessive bending and twisting of the blood vessels in the retina that is associated with numerous health...
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Interference in melanoma CD248 function reduces vascular mimicry and metastasis
BackgroundTumor vascular mimicry is an emerging issue that affects patient survival while having no treatment at the current moment. Despite several...
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Ischemic wound revascularization by the stromal vascular fraction relies on host-donor hybrid vessels
Nonhealing wounds place a significant burden on both quality of life of affected patients and health systems. Skin substitutes are applied to promote...
