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Mouse Corneal Transplantation
Corneal transplantation is the most common form of organ transplantation worldwide. Transplant survival depends on various factors, many of which are... -
Brown Adipose Tissue Transplantation
The metabolic benefits of brown adipose tissue (BAT) are well known. Increasing the BAT content and/or activity is a proposed therapeutic approach to... -
Immunology of Transplantation and Malignancy
Successful transplantation requires a multitude of important steps: surgical asepsis, development of surgical techniques of vascular anastomosis,... -
Monoclonal Antibodies in Solid Organ Transplantation
In an attempt to target solid organ transplant immunosuppression, monoclonal antibodies directed against key steps in specific immunologic pathways... -
Tolerance and Transplantation Immunology
In this chapter, we will first discuss about the impact and mechanisms of immunological tolerance, which is differentiated into central and... -
Subcutaneous Transplantation of White Adipose Tissue
In the research setting, white adipose tissue (WAT) transplantation, also known as fat transplantation, is often used to understand the physiological... -
Strategies to Upgrade the Stem Cell Application for Brain Transplantation
Introduction: Cerebral stem cellStem cell transplantation has the potential to replace dead cells and restore lost brain functions in... -
Hematopoietic stem cell transplantation for DLBCL: a report from the European Society for Blood and Marrow Transplantation on more than 40,000 patients over 32 years
Autologous(auto-) and allogeneic(allo-) hematopoietic stem cell transplantation (HSCT) are key treatments for relapsed/refractory diffuse large...
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Effect of Hematopoietic Stem Cell Transplantation and Post-Transplantation Cyclophosphamide on the Microglia Phenotype in Rats with Experimental Allergic Encephalomyelitis
Microglia are the resident immune cells of the central nervous system, playing a role in the inflammatory process development and resolution,...
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Carotid artery transplantation of brain endothelial cells enhances neuroprotection and neurorepair in ischaemic stroke rats
Brain microvascular endothelial cells (BMECs), an important component of the neurovascular unit, can promote angiogenesis and synaptic formation in...
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Mitochondrial transplantation as a novel therapeutic strategy for cardiovascular diseases
Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related death worldwide, and effective therapeutic strategies against...
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Mitochondrial transplantation as a possible therapeutic option for sarcopenia
AbstractWith advancing age, the skeletal muscle phenotype is characterized by a progressive loss of mass, strength, and quality. This phenomenon,...
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CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation
BackgroundThe immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that...
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Azithromycin for Other Lung Diseases: Lung Transplantation and Sarcoidosis
Azithromycin was introduced in lung transplantation in an attempt to improve the pulmonary function in patients with chronic allograft dysfunction... -
Mitochondrial Transportation, Transplantation, and Subsequent Immune Response in Alzheimer’s Disease: An Update
Alzheimer’s disease (AD) is a devastating neurodegenerative disease characterized by memory impairment and a progressive decline in cognitive...
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Neutrophil diversity and plasticity: Implications for organ transplantation
Neutrophils, as the first defenders against external microbes and stimuli, are highly active and finely regulated innate immune cells. Emerging...
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Uncommon Transplantation Sites: Transplantation of Islets and Islet Organoids in the Anterior Chamber of the Eye of Rodents and Monkeys
The anterior chamber of the eye is a highly vascularized and innervated location that is also particularly rich in oxygen and immune privileged. This... -
Long-term survivors demonstrate superior quality of life after haploidentical stem cell transplantation to matched sibling donor transplantation
BackgroundIt has been well-documented that haplo-identical hematopoietic stem cell transplantation (HID-HSCT) can provide outcomes comparable to...
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Cerebral organoids transplantation repairs infarcted cortex and restores impaired function after stroke
Stroke usually causes prolonged or lifelong disability, owing to the permanent loss of infarcted tissue. Although a variety of stem cell...
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Liver transplantation in metastatic colorectal cancer: are we ready for it?
Colorectal cancer (CRC) is a prevalent disease worldwide, with more than 50% of patients develo** metastases to the liver. Five-year overall...