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The epithelial–mesenchymal plasticity landscape: principles of design and mechanisms of regulation
Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several states across the epithelial–mesenchymal landscape, thereby...
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Noise Induced Depression-Like Behavior, Neuroinflammation and Synaptic Plasticity Impairments: The Protective Effects of Luteolin
Noise is a kind of sound that causes agitation and harms human health. Studies have shown that noise can lead to neuroinflammation, damage to...
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Epigenome plasticity in plants
Plant intra-individual and inter-individual variation can be determined by the epigenome, a set of covalent modifications of DNA and chromatin that...
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Ferulic Acid Improves Synaptic Plasticity and Cognitive Impairments by Alleviating the PP2B/DARPP-32/PP1 Axis-Mediated STEP Increase and Aβ Burden in Alzheimer’s Disease
The burden of Alzheimer’s disease, the most prevalent neurodegenerative disease, is increasing exponentially due to the increase in the elderly...
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Acute Sleep Deprivation-Induced Anxiety and Disruption of Hypothalamic Cell Survival and Plasticity: A Mechanistic Study of Protection by Butanol Extract of Tinospora cordifolia
Since sleep is a key homeostatic phenomenon of the body, therefore understanding the complex etiology of the neurological outcome of sleep...
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Systematic Input–Output Map** Reveals Structural Plasticity of VTA Dopamine Neurons-Zona Incerta Loop Underlying the Social Buffering Effects in Learned Helplessness
A common phenomenon called social buffering (SB), communication within conspecific animals is a benefit for a stressed individual to better recover...
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Sex-specific role of high-fat diet and stress on behavior, energy metabolism, and the ventromedial hypothalamus
BackgroundScientific evidence highlights the influence of biological sex on the relationship between stress and metabolic dysfunctions. However,...
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Adult Neurogenesis and Social Behavior: A Reciprocal Relationship
Neural plasticity refers to the brain’s life-long capacity to change itself functionally and structurally. Specifically, adult neurogenesis—a unique... -
Stressor control and regional inflammatory responses in the brain: regulation by the basolateral amygdala
Increasing evidence has connected the development of certain neuropsychiatric disorders, as well as neurodegenerative diseases, to stress-induced...
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Stress-related cellular pathophysiology as a crosstalk risk factor for neurocognitive and psychiatric disorders
In this narrative review, we examine biological processes linking psychological stress and cognition, with a focus on how psychological stress can...
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Delta-Opioid Receptors Play a Role in the Control of Selected Parameters Related to Stress and Brain Plasticity Under Non-stress and/or Stress Conditions
There is some evidence that delta-opioid receptors may be involved in the brain processes related to neuroprotection. The aim of the present studies...
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Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response
Glioma intratumoral heterogeneity enables adaptation to challenging microenvironments and contributes to therapeutic resistance. We integrated 914...
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Interactions of neuroimmune signaling and glutamate plasticity in addiction
Chronic use of drugs of abuse affects neuroimmune signaling; however, there are still many open questions regarding the interactions between...
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Emotional Tagging and Long-Term Memory Formation
Numerous studies support the notion that emotional arousal modulates the formation of long-term memories. The amygdala, a principal component of the... -
Neurobiology of Stress-Induced Tinnitus
Emotional stress has accompanied humans since the dawn of time and has played an essential role not only in positive selection and adaptation to an... -
Features of the Responses of the Protective Systems of the Brain in Adult Rats to Stressors and Lipopolysaccharide
Susceptibility and resistance to depression is determined by the actions of the stimuli provoking it, including stressors and inflammatory processes,...
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Activity-Based Anorexia, an Animal Model of Anorexia Nervosa for Investigating Brain Plasticity Underlying the Gain of Resilience
Anorexia nervosa (AN) is a mental illness characterized by continuously severe, self-imposed starvation and intense anxiety, manifested as fear of... -
Aerobic exercise promotes emotion regulation: a narrative review
Aerobic exercise improves the three stages of emotion regulation: perception, valuation and action. It reduces the perception of negative emotions,...
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Chronic Stress Induced by Kee** in Conditions of Nesting Material Deficiency in the Early Postnatal Period Affects Behavior and Stress Reactivity in Male Rats
Rodent models of deprivation of parental care are increasingly used to model depression-like disorders induced by early stress. The present study...
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Focal Dystonia and the Stress Network: The Role of Stress Vulnerability and Adverse Childhood Experiences in the Development of Musician’s Dystonia
Musician’s dystonia is often described as a neurological disorder, resulting from reduced inhibition in the basal ganglia and the cerebellum and...