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EMP3 as a prognostic biomarker correlates with EMT in GBM
BackgroundGlioblastoma (GBM) is the most aggressive malignant central nervous system tumor with a poor prognosis.The malignant transformation of...
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Integrated profiling identifies CACNG3 as a prognostic biomarker for patients with glioma
Gliomas are the most common malignant primary brain tumors in adults with poor prognoses. The purpose of this study is to explore CACNG3 as a...
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TIPARP as a prognostic biomarker and potential immunotherapeutic target in male papillary thyroid carcinoma
BackgroundMale patients with papillary thyroid carcinoma (PTC) tend to have poorer prognosis compared to females, partially attributable to a higher...
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Combined score based on plasma fibrinogen and platelet-lymphocyte ratio as a prognostic biomarker in esophageal squamous cell carcinoma
BackgroundIncreasing evidence has showed that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio...
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Comprehensive analysis identifies CLEC1B as a potential prognostic biomarker in hepatocellular carcinoma
BackgroundC-type lectin domain family 1 member B (CLEC1B, encoding the CLEC-2 protein), a member of the C-type lectin superfamily, is a type II...
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ZDHHC15 promotes glioma malignancy and acts as a novel prognostic biomarker for patients with glioma
BackgroundGlioma is the most common and aggressive tumor in the adult brain. Recent studies have indicated that Zinc finger DHHC-type...
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Integrating bioinformatics and experimental validation to unveil disulfidptosis-related lncRNAs as prognostic biomarker and therapeutic target in hepatocellular carcinoma
BackgroundHepatocellular carcinoma (HCC) stands as a prevalent malignancy globally, characterized by significant morbidity and mortality. Despite...
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Novel biomarker SARIFA in colorectal cancer: highly prognostic, not genetically driven and histologic indicator of a distinct tumor biology
SARIFA (Stroma AReactive Invasion Front Areas) has recently emerged as a promising histopathological biomarker for colon and gastric cancer. To...
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PCDH1, a poor prognostic biomarker and potential target for pancreatic adenocarcinoma metastatic therapy
BackgroundPancreatic adenocarcinoma (PAAD) is an aggressive solid tumour characterised by few early symptoms, high mortality, and lack of effective...
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GBP2 is a prognostic biomarker and associated with immunotherapeutic responses in gastric cancer
BackgroundThe interferon-induced protein known as guanylate-binding protein 2 (GBP2) has been linked to multiple different cancer types as an...
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ARHGAP39 is a prognostic biomarker involved in immune infiltration in breast cancer
BackgroundCurrent studies on the role of ARHGAP39 mainly focused on its effect on neurodevelopment. However, there are few studies on the...
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APOC1 is a prognostic biomarker associated with M2 macrophages in ovarian cancer
BackgroundRecent studies have demonstrated that APOC1 is associated with cancer progression, exerting cancer-promoting and immune...
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NGS-defined measurable residual disease (MRD) after initial chemotherapy as a prognostic biomarker for acute myeloid leukemia
Treated AML patients often have measurable residual disease (MRD) due to persisting low-level clones. This study assessed whether residual...
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Comprehensive analysis of BTNL9 as a prognostic biomarker correlated with immune infiltrations in thyroid cancer
BackgroundThyroid cancer (THCA) is the most common type of endocrine cancers, and the disease recurrences were usually associated with the risks of...
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An integrated pan-cancer analysis of leucine-rich repeat containing protein 59: a potential biomarker for prognostic and immunotherapy
Leucine-rich repeat containing protein 59 (LRRC59), a ribosome binding protein located on the endoplasmic reticulum and the nuclear envelope....
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KIF2C is a prognostic biomarker associated with immune cell infiltration in breast cancer
BackgroundThe kinesin-13 family member 2C (KIF2C) is a versatile protein participating in many biological processes. KIF2C is frequently up-regulated...
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LAG3 is an independent prognostic biomarker and potential target for immune checkpoint inhibitors in malignant pleural mesothelioma: a retrospective study
BackgroundLymphocyte-activation gene 3 (LAG3) is an immune checkpoint receptor; novel LAG3 immune checkpoint inhibitors (ICIs) exhibit therapeutic...
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The Concept of Stroma AReactive Invasion Front Areas (SARIFA) as a new prognostic biomarker for lipid-driven cancers holds true in pancreatic ductal adenocarcinoma
BackgroundPancreatic ductal adenocarcinoma (PDAC) is a ‘difficult-to-treat’ entity. To forecast its prognosis, we introduced a new biomarker, SARIFA...
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KNSTRN Is a Prognostic Biomarker That Is Correlated with Immune Infiltration in Breast Cancer and Promotes Cell Cycle and Proliferation
Kinetochore-localized astrin/SPAG5-binding protein (KNSTRN) promotes the progression of bladder cancer and lung adenocarcinoma. However, its...
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TET1 is a Diagnostic and Prognostic Biomarker Associated with Immune Infiltration in Papillary Thyroid Cancer
To investigate the function of ten-eleven translocation 1 (TET1) and its underlying mechanism in papillary thyroid cancer (PTC). Using the RNA-Seq...
