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Biomedicine

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Showing 1-20 of 23 results

  1. Critical appraisal of the piRNA-PIWI axis in cancer and cancer stem cells

    Small noncoding RNAs play an important role in various disease states, including cancer. PIWI proteins, a subfamily of Argonaute proteins, and...

    Elena Garcia-Borja, Frantisek Siegl, ... Jiri Sana in Biomarker Research
    Article Open access 01 February 2024

  2. Themes and variations on piRNA-guided transposon control

    PIWI-interacting RNAs (piRNAs) are responsible for preventing the movement of transposable elements in germ cells and protect the integrity of...

    Zuzana Loubalova, Parthena Konstantinidou, Astrid D. Haase in Mobile DNA
    Article Open access 02 September 2023

  3. piRNAs: biogenesis and their potential roles in cancer

    With the length of about 26–31 nt, PIWI-interacting RNA (piRNA) is a small non-coding RNA (ncRNA) that interacts with PIWI proteins to form the piRNA...

    Binghong Guo, Dongpei Li, ... **ao Zhu in Cancer and Metastasis Reviews
    Article 20 January 2020

  4. The role of piRNAs in predicting and prognosing in cancer: a focus on piRNA-823 (a systematic review and meta-analysis)

    Introduction

    This article examines the potential of using liquid biopsy with piRNAs to study cancer survival outcomes. While previous studies have...

    Mohammad Taghizadeh, Tohid Jafari-Koshki, ... Abbas Karimi in BMC Cancer
    Article Open access 16 April 2024

  5. A combined miRNA–piRNA signature in the serum and urine of rabbits infected with Toxoplasma gondii oocysts

    Background

    Increasing evidence has shown that non-coding RNA (ncRNA) molecules play fundamental roles in cells, and many are stable in body fluids as...

    Shi-Chen **e, Chun-Xue Zhou, ... **ng-Quan Zhu in Parasites & Vectors
    Article Open access 26 December 2022

  6. The potential emerging role of piRNA/PIWI complex in virus infection

    P-element-induced wimpy testis-interacting RNAs (piRNAs), a class of small noncoding RNAs with about 24–32 nucleotides, often interact with PIWI...

    Yanyan Li, Kai Wang, ... Yan Zhang in Virus Genes
    Article 04 June 2024

  7. Response of the mosquito immune system and symbiotic bacteria to pathogen infection

    Mosquitoes are the deadliest animal in the word, transmitting a variety of insect-borne infectious diseases, such as malaria, dengue fever, yellow...

    Man** Li, Yang Zhou, ... Yuan Shen in Parasites & Vectors
    Article Open access 17 February 2024

  8. Piwi-interacting RNAs (piRNAs) as potential biomarkers and therapeutic targets for cardiovascular diseases

    Cardiovascular diseases (CVDs) are the leading causes of death worldwide. Increasing reports demonstrated that non-coding RNAs (ncRNAs) have been...

    Min Li, Yanyan Yang, ... Tao Yu in Angiogenesis
    Article 04 October 2020

  9. Origins of Pluripotency: From Stem Cells to Germ Cells

    In this chapter, the basic concept of pluripotency is explored. You will learn about the origins of pluripotent stem cells, both in mice and in...
    Maria Gomes Fernandes, Susana M. Chuva de Sousa Lopes in Concepts and Applications of Stem Cell Biology
    Chapter 2020

  10. Exosomal Non-coding RNAs

    Cancer remains to be one of the major cause of morbidity and mortality worldwide with breast cancer being the most frequently diagnosed cancer among...
    Rajalakshmi Prakash, Kaumudi Pande, Anbarasu Kannan in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
    Reference work entry 2022

  11. Exosomal Non-coding RNAs

    Cancer remains to be one of the major cause of morbidity and mortality worldwide with breast cancer being the most frequently diagnosed cancer among...
    Rajalakshmi Prakash, Kaumudi Pande, Anbarasu Kannan in Handbook of Oxidative Stress in Cancer: Therapeutic Aspects
    Living reference work entry 2022

  12. Promoter methylation, transcription, and retrotransposition of LINE-1 in colorectal adenomas and adenocarcinomas

    Background

    The methylation of the CpG islands of the LINE-1 promoter is a tight control mechanism on the function of mobile elements. However,...

    Milad Shademan, Khadijeh Zare, ... Hesam Dehghani in Cancer Cell International
    Article Open access 01 September 2020

  13. flam piRNA precursors channel from the nucleus to the cytoplasm in a temporally regulated manner along Drosophila oogenesis

    Background

    PIWI-interacting RNAs (piRNAs) are the effectors of transposable element silencing in the reproductive apparatus. In Drosophila ovarian...

    Cynthia Dennis, Emilie Brasset, Chantal Vaury in Mobile DNA
    Article Open access 06 July 2019

  14. Mosquito antiviral defense mechanisms: a delicate balance between innate immunity and persistent viral infection

    Mosquito-borne diseases are associated with major global health burdens. Aedes spp. and Culex spp. are primarily responsible for the transmission of...

    Wai-Suet Lee, Julie A. Webster, ... Lara J. Herrero in Parasites & Vectors
    Article Open access 11 April 2019

  15. Analysis of RNA-Seq Data Using TEtranscripts

    Transposable elements (TE) are mobile genetic elements that can readily change their genomic position. When not properly silenced, TEs can contribute...
    Ying **, Molly Hammell in Transcriptome Data Analysis
    Protocol 2018

  16. Small RNA-based antimicrobial immunity

    Protection against microbial infection in eukaryotes is provided by diverse cellular and molecular mechanisms. Here, we present a comparative view of...

    Zhongxin Guo, Yang Li, Shou-Wei Ding in Nature Reviews Immunology
    Article 09 October 2018

  17. piRNAs-Transposon Silencing and Germ Line Development

    Transposable elements (TEs), can insert themselves independently into genomes and alter the genome structure and consequently the function of genes....
    Catherine Demoliou in Genomic Elements in Health, Disease and Evolution
    Chapter 2015

  18. RNome: Evolution and Nature

    In spite of identical genetic information, different types of the cells in the body perform their own specific functions. It is the differential...
    Mansi Arora, Deepak Kaul in Cancer RNome: Nature & Evolution
    Chapter 2018

  19. The piRNA Pathway Guards the Germline Genome Against Transposable Elements

    Transposable elements (TEs) have the capacity to replicate and insert into new genomic locations. This contributs significantly to evolution of...
    Katalin Fejes Tóth, Dubravka Pezic, ... Alexandre Webster in Non-coding RNA and the Reproductive System
    Chapter 2016

  20. Profiling of the small RNA populations in human testicular germ cell tumors shows global loss of piRNAs

    Background

    Small non-coding RNAs play essential roles in gene regulation, however, the interplay between RNA groups, their expression levels and...

    TB Rounge, K Furu, ... E Enerly in Molecular Cancer
    Article Open access 12 August 2015
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