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Does Pallidal Physiology Determine the Success of Unilateral Deep Brain Stimulation in Cervical Dystonia?
Pallidal deep brain stimulationDeep Brain Stimulation (DBS) is a well-known surgical treatment for cervical dystoniaCervical dystonia. The resolution...
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Angiotensin II increases the firing activity of pallidal neurons and participates in motor control in rats
The globus pallidus has emerged as a crucial node in the basal ganglia motor control circuit under both healthy and parkinsonian states. Previous...
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Anatomy of the Limbic System and Surgery for Medial Temporal Lesions
The limbic system is phylogenetically the oldest and functionally the most complex and least understood parts of the human brain [1]. The limbic...
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Pallidal stimulation as treatment for camptocormia in Parkinson’s disease
Camptocormia is a common and often debilitating postural deformity in Parkinson’s disease (PD). Few treatments are currently effective. Deep brain...
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Anatomy of Basal Forebrain and Orbital Cortical Approach to Caudate Head Tumors
The mediobasal frontal region harbors prominent gray matter masses and white matter connections and is an important component of the limbic system....
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Characterizing the Neural Substrate of Reward with the Use of Specific Brain Lesions
Examining the effects of brain lesions has been a key part of neuroscience since the earliest observations and research. Work using animal models...
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The Role of Cerebellum and Basal Ganglia Functional Connectivity in Altered Voluntary Movement Execution in Essential Tremor
Substantial evidence highlights the role of the cerebellum in the pathophysiology of tremor in essential tremor (ET), although its potential...
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Dystonia in Childhood: How Insights from Paediatric Research Enrich the Network Theory of Dystonia
Dystonia is now widely accepted as a network disorder, with multiple brain regions and their interconnections playing a potential role in the...
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Electrophysiological insights into deep brain stimulation of the network disorder dystonia
Deep brain stimulation (DBS), a treatment for modulating the abnormal central neuronal circuitry, has become the standard of care nowadays and is...
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Posttraumatic Tremor and Other Posttraumatic Movement Disorders
Trauma, defined as a form of mechanical stress, is followed by a series of reactions aimed to repair the damage, promote healing, and recruit host...
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Reinforcement Learning and Birdsong
The production of a birdsong is reminiscent of a central pattern generator, at least for birds with a singing repertoire: a neural circuit produces a...
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Diffusion Imaging in Tremor
Diffusion-weighted magnetic resonance imaging (DWI) of the brain is a magnetic resonance technique that probes the motion of free water undergoing...
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Neurophysiological insights in dystonia and its response to deep brain stimulation treatment
Dystonia is a movement disorder characterised by involuntary muscle contractions resulting in abnormal movements, postures and tremor. The...
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Neurodegenerative Diseases and Psychosocial Impairment
Neurodegenerative diseases (NDDs) are a group of disorders characterized by degeneration of the central and peripheral nervous system leading to a...
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Cerebellar Thalamic and Thalamocortical Projections
Although it is well known that the major output of the cerebellum is directed to the thalamus and ultimately to the cerebral cortex, the anatomical...
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Manual segmentation of the paraventricular nucleus of the hypothalamus and the dorsal and ventral bed nucleus of stria terminalis using multimodal 7 Tesla structural MRI: probabilistic atlases for a stress-control triad
The paraventricular nucleus of the hypothalamus (PVN) is uniquely capable of proximal control over autonomic and neuroendocrine stress responses, and...
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Deep Brain Stimulation for Tremor
Tremor is one of the most frequent complaints in the movement disorder clinic. Not only it can be encountered in multiple different syndromes, but it...
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Corticostriatal Circuitry
The cortico network plays a central role develo** appropriate goal-directed behaviors, including the motivation and cognition to develop...
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Input-output specific orchestration of aversive valence in lateral habenula during stress dynamics
Stress has been considered as a major risk factor for depressive disorders, triggering depression onset via inducing persistent dysfunctions in...
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Anatomical characterisation of three different psychosurgical targets in the subthalamic area: from the basal ganglia to the limbic system
Effective neural stimulation for the treatment of severe psychiatric disorders needs accurate characterisation of surgical targets. This is...
