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Unique morphology and photoperiodically regulated activity of neurosecretory canopy cells in the pond snail Lymnaea stagnalis
The pond snail Lymnaea stagnalis exhibits clear photoperiodism in egg laying; it lays more eggs in long-day conditions than in medium-day conditions....
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Histological investigation of the effects of fenoxycarb on neurosecretory cells in the silkworm, Bombyx mori brain
Fenoxycarb 0-ethyl N-(2-(4-pheoxyphenoxy)-ethyl) carbamate is the most potent juvenile hormone analogue against a variety of insect species including...
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Differential expression of ITP and ITPL indicate multiple functions in the silkworm Bombyx mori
Ion transport peptide (ITP) and a longer ITP-like (ITPL) are alternatively spliced insect neuropeptides involved in the regulation of development and...
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Armen Anushavanovich Galoyan and His Scientific School
Abstract —Armen Galoyan is an outstanding modern neurobiologist and a founder of the scientific neurochemical school. He discovered neurohormones K,...
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Culture of Neuron and Glia Cells
The mammalian nervous system consists of neurons that transmit the coordinated neuronal signals throughout the body and glia or supporting cells that...
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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS
The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and whose composition changes as a function of an animal’s...
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Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown
Peptide-containing vesicles are an evolutionarily ancient way by which cells communicate. Most, if not all, neurons release peptides within the...
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Single-cell analysis of mesenchymal cells in permeable neural vasculature reveals novel diverse subpopulations of fibroblasts
BackgroundIn the choroid plexus and pituitary gland, vasculature is known to have a permeable, fenestrated phenotype which allows for the free...
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SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier
BackgroundAs a consequence of SARS-CoV-2 infection various neurocognitive and neuropsychiatric symptoms can appear, which may persist for several...
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Mechanism of Molecular Activity of Yolkin—a Polypeptide Complex Derived from Hen Egg Yolk—in PC12 Cells and Immortalized Hippocampal Precursor Cells H19-7
Food-derived bioactive peptides able to regulate neuronal function have been intensively searched and studied for their potential therapeutic...
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Cellular and Molecular Roles of Immune Cells in the Gut-Brain Axis in Migraine
Migraine is a complex and multi-system dysfunction. The realization of its pathophysiology and diagnosis is develo** rapidly. Migraine has been...
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Lysosomal and synaptic dysfunction markers in longitudinal cerebrospinal fluid of de novo Parkinson’s disease
Lysosomal and synaptic dysfunctions are hallmarks in neurodegeneration and potentially relevant as biomarkers, but data on early Parkinson’s disease...
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6-Hydroxydopamine Induces Neurodegeneration in Terminally Differentiated SH-SY5Y Neuroblastoma Cells via Enrichment of the Nucleosomal Degradation Pathway: a Global Proteomics Approach
The SH-SY5Y human neuroblastoma cells have been used for decades as a cell-based model of dopaminergic neurons to explore the underlying science of...
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Axotomy results in an increase in Thy-1 protein in the 35-day-old rat supraoptic nucleus
We demonstrated previously that the hypothalamic supraoptic nucleus (SON) undergoes an axonal sprouting response following a unilateral lesion of the...
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Morpho-Functional Study of Cardioactive Neurohormones and Some Other Neuropeptides in the Nervous and Cardiac Systems of Rats in Normal and Pathological Conditions
AbstractThis review presents data from multilateral studies, aimed at determining the localization, release and the function of the cardioactive...
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Captopril exhibits protective effects through anti-inflammatory and anti-apoptotic pathways against hydrogen peroxide-induced oxidative stress in C6 glioma cells
Recent studies have shown that angiotensin-converting enzyme (ACE) inhibitors have reduced oxidative damage in the central nervous system (CNS)....
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Considerations for the Use of SH-SY5Y Neuroblastoma Cells in Neurobiology
The use of primary mammalian neurons derived from embryonic central nervous system tissue is limited by the fact that once terminally differentiated...
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The Neurohypophysis and Urophysis: Ancient Piscine Neurovascular Interfaces
Vertebrate homoeostasis is regulated by secretion of neurohormones from specialized neuroendocrine neurovascular interfaces such as the...
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Fine Chemo-anatomy of Hypothalamic Magnocellular Vasopressinergic System with an Emphasis on Ascending Connections for Behavioural Adaptation
This chapter is complementary to Chap. 6 and presents an overview of recent research progress concerning the fine chemo-anatomy of hypothalamic...
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Expression analysis of peptidergic enteroendocrine cells in the silkworm Bombyx mori
Enteroendocrine cells (ECs) in the insect midgut respond to physiological changes in the intestine by releasing multiple peptides to control food...
