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Molecular fingerprints of nuclear genome and mitochondrial genome for early diagnosis of lung adenocarcinoma
BackgroundLung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer with high morbidity and mortality rates. Due to the heterogeneity...
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Mitochondrial genome study in blood of maternally inherited ALS cases
BackgroundALS is a heterogeneous disease in which different factors such as mitochondrial phenotypes act in combination with a genetic...
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CRISPR/Cas9-mediated base editors and their prospects for mitochondrial genome engineering
Base editors are a type of double-stranded break (DSB)-free gene editing technology that has opened up new possibilities for precise manipulation of...
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A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome
BackgroundG-quadruplex DNA (G4) is a non-canonical structure forming in guanine-rich regions, which play a vital role in cancer biology and are now...
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The Complete Mitochondrial Genome of the Mashen Pig (Sus scrofa)
AbstractMashen pig ( Sus scrofa ) is one of the famous local breeds in China. In this study, we sequenced and reported the complete mitochondrial...
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Mitochondrial DNA Evolution Trends of Baikal Endemic Sponges. I. The Mitochondrial Genome of S. khanaevi
The nucleotide sequence of the mitochondrial genome of a new species of sponge from the Baikal endemic family Lubomirskiidae, Swartschewskia khanaevi, ...
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Trends and prospects in mitochondrial genome editing
Mitochondria are of fundamental importance in programmed cell death, cellular metabolism, and intracellular calcium concentration modulation, and...
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Dissecting the sequential evolution of a selfish mitochondrial genome in Caenorhabditis elegans
Mitochondrial genomes exist in a nested hierarchy of populations where mitochondrial variants are subject to genetic drift and selection at each...
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The complete mitochondrial genome of the rodent flea Nosopsyllus laeviceps: genome description, comparative analysis, and phylogenetic implications
BackgroundFleas are one of the most common and pervasive ectoparasites worldwide, comprising at least 2500 valid species. They are vectors of several...
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Organization and expression of the mammalian mitochondrial genome
The mitochondrial genome encodes core subunits of the respiratory chain that drives oxidative phosphorylation and is, therefore, essential for energy...
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A new long-read mitochondrial-genome protocol (PacBio HiFi) for haemosporidian parasites: a tool for population and biodiversity studies
BackgroundStudies on haemosporidian diversity, including origin of human malaria parasites, malaria's zoonotic dynamic, and regional biodiversity...
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Mitochondrial genome of the fluke pond snail, Austropeplea cf. brazieri (Gastropoda: Lymnaeidae)
BackgroundLymnaeid snails of the genus Austropeplea are an important vector of the liver fluke ( Fasciola hepatica ), contributing to livestock...
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The Complete Mitochondrial Genome of Capitulum mitella with Characterization and Phylogenetic Implications
AbstractThis study aimed to provide new insights into the mitogenomic data of the intertidal coastal ecosystem species Capitulum mitella from China....
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The Complete Mitochondrial Genome of Littoraria ardouiniana (Heude, 1885) (Gastropoda, Littorininae): Sequence, Structure, and Phylogenetic Analyses
AbstractThe genus Littoraria plays a significant role in the ecology of intertidal communities and is one of the very few molluscan groups that are...
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Comparative Analysis of the Complete Mitochondrial Genome Sequence of an Alpine Plant Triosteum pinnatifidum
Abstract —In this study, the complete mitochondrial genome (mt genome) of Triosteum pinnatifidum was investigated for the first time. The mt genome...
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The complete mitochondrial genome of Morishitium polonicum (Trematoda, Cyclocoelidae) and its phylogenetic implications
Trematodes can adversely impact the health and survival of wild animals. The trematode family Cyclocoelidae, which includes large digenean bird...
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The Characterization of Mitochondrial Genome of Spotted Pond Turtle (Geoclemys hamiltonii)
The spotted pond turtle Geoclemys hamiltonii (Gray, 1830) is widely distributed in the Indus, Ganges, and Brahmaputra river basins. In this study,...
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The Complete Mitochondrial Genome of the Goitered Gazelle (Gazella subgutturosa hillieriana) from Ningxia Hui Autonomous Region, China
AbstractThe Mongolian subspecies of Goitred Gazelle ( Gazella subgutturosa hillieriana ) belongs to Artiodactyla and Bovidae. It is widely distributed...
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Mitochondrial DNA Profiling
Mitochondrial DNA (mtDNA) is a versatile tool in understanding the clinical and non-clinical aspects attributed by the nucleotide sequences. The...