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Evaluation of Microwave Vacuum Drying as an Alternative to Freeze-Drying of Biologics and Vaccines: the Power of Simple Modeling to Identify a Mechanism for Faster Drying Times Achieved with Microwave
Vial-based lyophilization for biopharmaceuticals has been an indispensable cornerstone process for over 50 years. However, the process is not without...
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Innovative Technologies for Improving the Sustainability of the Food Drying Industry
Purpose of ReviewDrying as a preservation method for plant materials improves microbial and nutritional quality, however, such processing needs a lot...
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Drying Technologies for Vaccines
This chapter begins with liquid and solid vaccine formulation approaches and discusses the advantages and limitations. This is followed by a...
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Drying
Drying is one of the most common unit operations in pharmaceutical manufacturing. Selection of dryers for pharmaceutical manufacturing is not simple,...
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Aseptic Spray Drying Technology
This chapter is dedicated to aseptic spray drying technology. The reader will learn the key elements for the design and components for constructing...
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Microwave-Assisted Extraction of Phytochemicals
Microwave-assisted extraction (MAE) has emerged as a promising technique for the extraction of phytochemicals and has received substantial scientific...
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Loss-on-Drying Prediction for a Vibrated Fluidised Bed Dryer by Means of Mass and Energy Balances
PurposeContinuous wet granulation and drying require an adequate process control strategy to ensure the product quality. The most important critical...
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Recent progress in drying technologies for improving the stability and delivery efficiency of biopharmaceuticals
BackgroundMost biopharmaceuticals are developed in liquid dosage forms that are less stable than solid forms. To ensure the stability of...
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Enhancement of Valsartan Oral Bioavailability by Preparing a Microwave-Irradiated Inclusion Complex with Sulfobutyl Ether β-Cyclodextrin Using a Central Composite Face Design for Optimising Process Parameters
The purpose of the study is to investigate the influence of sulfobutyl ether β-cyclodextrin (SBE 7 -β-CD) on the bioavailability of valsartan. Phase...
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Conclusions and Future Perspectives of Spray-Dried Vaccines
This chapter offers a condensed summary of the main findings from the preceding Chaps. 1 to 6...
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Tissue Processing
Tissue processing is the technique by which fixed tissues are made suitable for embedding within a supportive medium such as paraffin, and consists...
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A Novel Preparation Method for Effervescent Tablets of **anganfang Containing Fresh Juice using a Semi-Solid Extrusion 3D Printer with Three Cartridge Holders
This study aimed to prepare effervescent tablets of traditional Chinese medicine **anganfang with fresh juice using a semi-solid 3D printer with...
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Functionalized Green Carbon dots for Specific Detection of Copper in Human Serum Samples and Living Cells
Intracellular copper ion (Cu 2+ ) is irreplaceable and essential in regulation of physiological and biological processes, while excessive copper from...
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Scale-Up of Nanoparticle Manufacturing Process
Nanoparticles owning a particle size of less than 100 nm have versatile use in the pharmaceutical industry. Different nanoparticles have been...
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Application of Direct and Indirect Non-thermal Plasma in the Development of Ready-to-Eat Foods
Purpose of ReviewThe studies of the application of non-thermal plasma (NTP) for food processing and preservation during the last 5 years have been...
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Multiplex Fluorescent Immunohistochemistry for Preservation of Tumor Microenvironment Architecture and Spatial Relationship of Cells in Tumor Tissues
The tumor microenvironment (TME), composed of immune cells, antigens, and local soluble factors, is integral to cancer development and progression....
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Assessing the Interrelationship of Microstructure, Properties, Drug Release Performance, and Preparation Process for Amorphous Solid Dispersions Via Noninvasive Imaging Analytics and Material Characterization
PurposeThe purpose of this work is to evaluate the interrelationship of microstructure, properties, and dissolution performance for amorphous solid...
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Pectin and Pectin Derivative-Based Films
Increasing usage of synthetic packaging films has driven to significant ecological problems. Consumers are now shifting to biodegradable,...
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Role of Block Copolymers in the Enhancement of Poor Solubility of Drugs
Low water solubility is the fundamental challenge in formulating both branded and generic formulations, which could result in insufficient absorption...
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From Bin to Benefit: Sustainable Valorization of Grapefruit (Citrus paradisi) Byproducts Towards the Circular Economy
Purpose of ReviewThis study aims to communicate updated information on the recent innovations in grapefruit byproduct valorization.
Recent Finding ...