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  1. Tumor Microenvironment

    In this chapter, we will learn that the tumor microenvironment is a stroma of normal cells supporting cancer cells. Tumors act like parasites that...
    Carsten Carlberg, Eunike Velleuer, Ferdinand Molnár in Molecular Medicine
    Chapter 2023
  2. Tumor Microenvironment: Multiway Role in Drug Resistance

    The tumor microenvironment (TME) is an ecosystem that surrounds a tumor inside the body. TME contains a complex and dynamic system that consists of...
    Ishfaq Majid Hurra, Mubashir J. Mintoo, ... Sameer Ullah Khan in Drug Resistance in Cancer: Mechanisms and Strategies
    Chapter 2024
  3. Introduction to Tumor Microenvironment

    The knowledge of tumor microenvironment (TME) has grown exponentially in recent decades. TME is a complex milieu with an essential role in tumor...
    Sara Momtazmanesh, Nima Rezaei in Handbook of Cancer and Immunology
    Living reference work entry 2023
  4. Basic Insights into Tumor Microenvironment in Prostate Cancer

    Prostate cancer, a prominent malignancy impacting men worldwide, is characterized by a dynamic and intricate interplay between cancer cells and their...
    Sanja Mijatović, Danijela Maksimović-Ivanić in Prostate Cancer
    Chapter 2024
  5. The Tumor Microenvironment

    The microenvironment of cancerous tissue consists of inflammatory cells, immune cells, blood vessels, neuroendocrine cells, myofibroblasts,...
    Thomson Alex, Damanpreet K. Lang, ... Zeenat Iqbal in Polymeric nanoparticles for the treatment of solid tumors
    Chapter 2022
  6. The immunosuppressive landscape in tumor microenvironment

    Recent advances in cancer immunotherapy, especially immune checkpoint inhibitors (ICIs), have revolutionized the clinical outcome of many cancer...

    Wuyi Liu, Huyue Zhou, ... Guobing Li in Immunologic Research
    Article 01 May 2024
  7. The Tumor Microenvironment Methods and Protocols

    This second edition provides update and new chapters detailing core and emerging in vitro and in vivo protocols.  Chapters guide readers through...

    Josie Ursini-Siegel in Methods in Molecular Biology
    Book 2023
  8. Tumor Microenvironment and Tumor-Targeted Therapy

    Cancer tissue or cancer cells do not exist in isolation, but start life within the microenvironment called tumor microenvironment (TME). The...
    Hongxia Duan, Wei Huang in Handbook of Cancer and Immunology
    Living reference work entry 2023
  9. Towards targeting the breast cancer immune microenvironment

    The tumour immune microenvironment is shaped by the crosstalk between cancer cells, immune cells, fibroblasts, endothelial cells and other stromal...

    Michael A. Harris, Peter Savas, ... Sherene Loi in Nature Reviews Cancer
    Article 05 July 2024
  10. Microenvironment of Cancer Stem Cells

    Microenvironment of cancer stem cells (CSCs) consists of a variety of cells and inter-cellular matrix and communications of the components. The...
    Chapter 2022
  11. Decellularized Extracellular Matrix for Modeling Cardiac Extracellular Microenvironment

    The extracellular matrix (ECM) forms most of the tissue microenvironment and is in a constant and dynamic equilibrium with cells. The...
    Franca Di Meglio, Daria Nurzynska, ... Clotilde Castaldo in Experimental Models of Cardiovascular Diseases
    Protocol 2024
  12. Hypoxic Tumor Microenvironment: Driver for Cancer Progression

    Hypoxia or low oxygen concentration is one of the major physiological parameters within tumor microenvironment (TME). It has a profound effect in...
    Chapter 2023
  13. Targeting metabolism to enhance immunotherapy within tumor microenvironment

    Cancer metabolic reprogramming has been considered an emerging hallmark in tumorigenesis and the antitumor immune response. Like cancer cells, immune...

    **ao-hui Liang, **n-yi Chen, ... **n Luan in Acta Pharmacologica Sinica
    Article 29 May 2024
  14. Breast Tumor Microenvironment and CDKs

    Breast malignancy is one of the most frequently diagnosed carcinoma in women globally, and it is also the common reason for tumor-associated fatality...
    Manzoor Ahmad Mir, Abrar Yousuf Mir in Therapeutic potential of Cell Cycle Kinases in Breast Cancer
    Chapter 2023
  15. Revam** Anticancer Strategies by Modulating Tumor Microenvironment Using Botanicals

    The successful development and progression of cancer is dependent not only upon the growth and proliferation of transformed cells but relies equally...
    Chapter 2024
  16. Cancer organoids 2.0: modelling the complexity of the tumour immune microenvironment

    The development of neoplasia involves a complex and continuous interplay between malignantly transformed cells and the tumour microenvironment (TME)....

    Roel Polak, Elisa T. Zhang, Calvin J. Kuo in Nature Reviews Cancer
    Article 08 July 2024
  17. How chemokines organize the tumour microenvironment

    For our immune system to contain or eliminate malignant solid tumours, both myeloid and lymphoid haematopoietic cells must not only extravasate from...

    Thorsten R. Mempel, Julia K. Lill, Lukas M. Altenburger in Nature Reviews Cancer
    Article 08 December 2023
  18. Tumor Microenvironment-Responsive Nanoplatforms for Triggering Drug Delivery

    Cancer is the second leading cause of mortality among nontransmissible diseases globally. Despite the advances in chemotherapy, the insufficient drug...
    Francesco Melia, Palita Udomjarumanee, ... Md Zahidul Islam Pranjol in Handbook of Cancer and Immunology
    Living reference work entry 2024
  19. Function of alveolar macrophages in lung cancer microenvironment

    Background

    Cancer tissues contain a wide variety of immune cells that play critical roles in suppressing or promoting tumor progression. Macrophages...

    Takahiro Matsui, Seiji Taniguchi, Masaru Ishii in Inflammation and Regeneration
    Article Open access 08 May 2024
  20. Single-cell atlas reveals the immunosuppressive microenvironment and Treg cells landscapes in recurrent Glioblastoma

    Patients diagnosed with glioblastoma (GBM) have the most aggressive tumor progression and lethal recurrence. Research on the immune microenvironment...

    **ngdong Wang, Yizhi Ge, ... Hengzhu Zhang in Cancer Gene Therapy
    Article 01 March 2024
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