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  1. Isoflurane Preconditioning Alleviates Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Inhibiting miR-195-3p Expression

    To investigate the role of microRNA-195-3p (miR-195-3p) in hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury. AC16 human cardiomyocyte cells...

    **aofei Han, Hongyuan Kan, ... **nyu Yao in Cardiovascular Toxicology
    Article 08 May 2024
  2. Hsa-miR-195-5p Inhibits Autophagy and Gemcitabine Resistance of Lung Adenocarcinoma Cells via E2F7/CEP55

    Lung adenocarcinoma (LUAD) is a common malignancy. Many studies have shown that LUAD is resistant to gemcitabine chemotherapy, resulting in poor...

    Linhai Fu, Zhupeng Li, ... Guangmao Yu in Biochemical Genetics
    Article 19 January 2023
  3. LINC00511 enhances LUAD malignancy by upregulating GCNT3 via miR-195-5p

    Background

    Accumulating evidence suggests that LINC00511 acts as an oncogenic long non-coding RNA (lncRNA) in various cancers, including lung...

    Youyi Zhang, ** **ao, **aobo Hu in BMC Cancer
    Article Open access 10 April 2022
  4. Construction of lncRNA TYMSOS/hsa-miR-101-3p/CEP55 and TYMSOS/hsa-miR-195-5p/CHEK1 Axis in Non-small Cell Lung Cancer

    As novel master regulators of initiation and progression, long non-coding RNAs (lncRNAs) can response to therapy in a wide variety of malignances....

    Longtao Ji, Ting Yang, ... Li** Dai in Biochemical Genetics
    Article 09 November 2022
  5. Circular RNA circMMP1 Contributes to the Progression of Glioma Through Regulating TGIF2 Expression by Sponging miR-195-5p

    Glioma is characterized by high morbidity and mortality worldwide. Circular RNA (circRNA) matrix metallopeptidase 1 (circMMP1, hsa_circ_0024108) was...

    Kuiming Zhang, Qi Wang, ... Zhen Liu in Biochemical Genetics
    Article 01 September 2021
  6. Long noncoding RNA TINCR facilitates hepatocellular carcinoma progression and dampens chemosensitivity to oxaliplatin by regulating the miR-195-3p/ST6GAL1/NF-κB pathway

    Background

    Long non-coding RNAs (lncRNA) have an essential role in progression and chemoresistance of hepatocellular carcinoma (HCC). In-depth study...

    Jie Mei, Wen** Lin, ... Rong** Guo in Journal of Experimental & Clinical Cancer Research
    Article Open access 03 January 2022
  7. Circular RNA-DPP4 serves an oncogenic role in prostate cancer progression through regulating miR-195/cyclin D1 axis

    Background

    Recently, more and more studies have highlighted the critical regulatory roles of circular RNAs (circRNAs), a class of non-coding RNAs, in...

    De** Yang, Bo Yang, ... Jianghua Zheng in Cancer Cell International
    Article Open access 16 July 2021
  8. PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1/miR-195-5p axis-dependent manner in hepatocellular carcinoma

    Background

    Sorafenib is a standard first-line treatment for advanced hepatocellular carcinoma (HCC), yet its effectiveness is often constrained....

    Jiarui Li, Yilan Li, ... Zhongjun Wu in Journal of Experimental & Clinical Cancer Research
    Article Open access 14 May 2024
  9. Circular RNA circ_001422 promotes the progression and metastasis of osteosarcoma via the miR-195-5p/FGF2/PI3K/Akt axis

    Background

    Circular RNAs (circRNAs) are involved in diverse processes that drive cancer development. However, the expression landscape and mechanistic...

    Bingsheng Yang, Lutao Li, ... Lijun Lin in Journal of Experimental & Clinical Cancer Research
    Article Open access 16 July 2021
  10. LncRNA LUADT1 sponges miR-195 to prevent cardiac endothelial cell apoptosis in sepsis

    Background

    The oncogenic role of the newly identified lncRNA LUADT1 has been revealed in lung adenocarcinoma. It was reported that LUADT1 plays a...

    Zhimin Zhang, Mingzhu Lv, ... Lihua Wang in Molecular Medicine
    Article Open access 23 November 2020
  11. Interferon regulatory factor 1 (IRF-1) downregulates Checkpoint kinase 1 (CHK1) through miR-195 to upregulate apoptosis and PD-L1 expression in Hepatocellular carcinoma (HCC) cells

    Background

    CHK1 is considered an oncogene with overexpression in numerous cancers. However, CHK1 signalling regulation in hepatocellular carcinoma...

    Yihe Yan, Leting Zheng, ... David A. Geller in British Journal of Cancer
    Article 26 March 2021
  12. Novel LncRNA OXCT1-AS1 indicates poor prognosis and contributes to tumorigenesis by regulating miR-195/CDC25A axis in glioblastoma

    Background

    Long noncoding RNAs (lncRNAs) contribute to multiple biological processes in human glioblastoma (GBM). However, identifying a specific...

    Chen Zhong, Qian Yu, ... Gao Chen in Journal of Experimental & Clinical Cancer Research
    Article Open access 08 April 2021
  13. RETRACTED ARTICLE: NF-κB maintains the stemness of colon cancer cells by downregulating miR-195-5p/497–5p and upregulating MCM2

    Background

    Colon cancer represents one of the leading causes of gastrointestinal tumors in industrialized countries, and its incidence appears to be...

    Longgang Wang, **xiang Guo, ... Lei Zhou in Journal of Experimental & Clinical Cancer Research
    Article Open access 28 October 2020
  14. Circ_ZFR contributes to the paclitaxel resistance and progression of non-small cell lung cancer by upregulating KPNA4 through sponging miR-195-5p

    Background

    A growing body of evidence has demonstrated the vital roles of circular RNAs (circRNAs) in cancer progression and drug resistance. We...

    Junmin Li, Rongmei Fan, Hui **ao in Cancer Cell International
    Article Open access 06 January 2021
  15. LncRNA DLX6-AS1 aggravates the development of ovarian cancer via modulating FHL2 by sponging miR-195-5p

    Background

    Ovarian cancer (OC) is a huge burden on women’s lives. Recently, the implication of long non-coding RNAs (lncRNAs) in cancers, including...

    Lijun Kong, Chengyan Zhang in Cancer Cell International
    Article Open access 05 August 2020
  16. LncRNA MEG3 Participates in Caerulein-Induced Inflammatory Injury in Human Pancreatic Cells via Regulating miR-195-5p/FGFR2 Axis and Inactivating NF-κB Pathway

    Acute pancreatitis (AP) is a dysfunctional pancreas disease marked by severe inflammation. Long non-coding RNAs (lncRNAs) involving in the regulation...

    **nghai Chen, Debiao Song in Inflammation
    Article 27 August 2020
  17. RETRACTED ARTICLE: Isoliquiritigenin downregulates miR-195 and attenuates oxidative stress and inflammation in STZ-induced retinal injury

    Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus that leads to significant vision loss. Isoliquiritigenin (ISL)...

    Sharifa Alzahrani, Sadeem M. Ajwah, ... Nehal M. Elsherbiny in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 22 July 2020
  18. Retraction Note to: The circRNA circAGFG1 acts as a sponge of miR-195-5p to promote triple-negative breast cancer progression through regulating CCNE1 expression

    This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12943-018-0933-7.

    Rui Yang, Lei **ng, ... Junxia Chen in Molecular Cancer
    Article Open access 08 July 2022
  19. Circ_LDLR promoted the development of papillary thyroid carcinoma via regulating miR-195-5p/LIPH axis

    Background

    Emerging studies have demonstrated that circular RNAs (circRNAs) are key regulators for tumorigenesis in cancers, including papillary...

    **aolong Gui, Yan Li, ... Wenlong Cao in Cancer Cell International
    Article Open access 15 June 2020
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