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Lymphocyte recovery from radiation-induced lymphopenia in locally advanced esophageal squamous cell carcinoma: correlations with prognosis and lymphocyte-related organs
BackgroundLimited studies explored the relationship between lymphocyte recovery after definitive concurrent chemoradiotherapy (dCCRT) and prognosis...
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The prognostic role of pre-treatment neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in esophageal squamous cell carcinoma treated with concurrent chemoradiotherapy
PurposeIn this study, we retrospectively investigated the prognostic role of pre-treatment neutrophil to lymphocyte ratio (NLR) and platelet to...
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Lymphocyte-Directed Immunomodulation Remits Thymoma-Associated Autoimmune Pneumonitis
BackgroundThymoma presents with several autoimmune manifestations and is associated with secondary autoimmune regulator (AIRE) deficiency....
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Membrane organization by tetraspanins and galectins shapes lymphocyte function
Immune receptors are not randomly distributed at the plasma membrane of lymphocytes but are segregated into specialized domains that function as...
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Monitoring trends in the absolute lymphocyte count and the neutrophil-to-lymphocyte ratio in patients with breast cancer receiving eribulin
BackgroundStudies have shown that the absolute lymphocyte count (ALC) and the neutrophil-to-lymphocyte ratio (NLR) are related to the outcomes in...
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The reference ranges and characteristics of lymphocyte parameters and the correlation between lymphocyte parameters and routine health indicators in adults from China
BackgroundAssessment of immune function is of key importance in recognition of disease or healthy status, which still faces challenge in clinical...
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Association between body fat distribution and B-lymphocyte subsets in peripheral blood
BackgroundObesity is associated with chronic low-grade inflammation, which is underpinned by the presence of elevated levels of circulating...
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Gut microbiota regulation of T lymphocyte subsets during systemic lupus erythematosus
BackgroundSystemic lupus erythematosus (SLE) is an autoimmune disease characterized by disturbance of pro-inflammatory and anti-inflammatory...
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Flow Cytometry Assessment of Lymphocyte Populations Infiltrating Liver Tumors
Tissue-resident and recruited immune cells are essential mediators of natural and therapy-induced immunosurveillance of liver neoplasia. This idea... -
Lymphocyte migration regulation related proteins in urine exosomes may serve as a potential biomarker for lung cancer diagnosis
BackgroundThe migration of lymphocytes shares many similarities in mode and mechanism with the metastasis of lung cancer tumor cells. But changes in...
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Dysbiosis of the Gut Microbiota in Patients with Psoriatic Arthritis is Closely Related to Lymphocyte Subsets and Cytokines
The purpose of this research was to characterize the microbiota of patients with psoriatic arthritis (PsA) and to compare the relationship between...
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Exploring the prognostic impact of absolute lymphocyte count in patients treated with immune-checkpoint inhibitors
BackgroundThe role of immune checkpoint inhibitors (ICI) expands but affordable and reproducible prognostic biomarkers are needed. We investigated...
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A simple tool for evaluation of inflammation in psoriasis: Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio as markers in psoriasis patients and related murine models of psoriasis-like skin disease
AbstractObjective parameters to quantify psoriatic inflammation are needed for interdisciplinary patient care, as well as preclinical experimental...
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Cytotoxic T-lymphocyte-associated 4 protein expression is associated with a high international prognostic score in advanced-stage classical Hodgkin lymphoma
ObjectiveTwenty percent of all classical Hodgkin lymphoma (CHL) cases relapse and recur, especially in advanced stages with a high International...
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Cytokines and lymphocyte subsets are associated with disease severity of severe fever with thrombocytopenia syndrome
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome...
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Influence of cryoablation versus operation on circulating lymphocyte subsets in patients with early-stage renal cell carcinoma
Immune response is known to play an important role in local tumor control especially in renal cell carcinoma (RCC), which is considered highly...
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Combined score based on plasma fibrinogen and platelet-lymphocyte ratio as a prognostic biomarker in esophageal squamous cell carcinoma
BackgroundIncreasing evidence has showed that inflammatory biomarkers, including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio...
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Characteristics of lymphocyte subset alterations in COVID-19 patients with different levels of disease severity
BackgroundCoronavirus disease 2019 (COVID-19) is a respiratory disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which...
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Tumor-Infiltrating Lymphocyte (TIL) Therapy
Since T cells can recognize tumor-associated antigens and eliminate cancer cells, preclinical and clinical developments of therapy have been... -
Is higher lymphocyte count a potential strategy for preventing chronic kidney disease in patients receiving long-term dasatinib treatment?
BackgroundDasatinib, which is used to treat treating chronic myeloid leukemia, induces increases in blood lymphocytes during the treatment. In...