Search
Search Results
-
Visualization of the Spatiotemporal Propagation of Interictal Spikes in Temporal Lobe Epilepsy: A MEG Pilot Study
Magnetoencephalography (MEG) is clinically used to localize interictal spikes in discrete brain areas of epilepsy patients through the equivalent...
-
GABAB Inhibition through Feedback Is Involved in the Synchronization of Interictal Spikes in the Cortex
Recent studies have significantly expanded our understanding of the functions of GABAergic interneurons in cortical neural networks. Interneurons of...
-
Reverse Inhibitory Connections via GABAB-Receptors Synchronize Interictal Discharges in the Cortex
Current experimental evidence shows that interictal discharges consist of a short spike and a slow wave, which is regarded as long-lasting...
-
Cell to network computational model of the epileptic human hippocampus suggests specific roles of network and channel dysfunctions in the ictal and interictal oscillations
The mechanisms underlying the generation of hippocampal epileptic seizures and interictal events and their interactions with the sleep-wake cycle are...
-
Epileptic seizure focus detection from interictal electroencephalogram: a survey
Electroencephalogram (EEG) is one of most effective clinical diagnosis modalities for the localization of epileptic focus. Most current AI solutions...
-
Seizure onset zone identification using phase-amplitude coupling and multiple machine learning approaches for interictal electrocorticogram
Automatic seizure onset zone (SOZ) localization using interictal electrocorticogram (ECoG) improves the diagnosis and treatment of patients with...
-
Interictal epileptiform discharges changed epilepsy-related brain network architecture in BECTS
To investigate directed information flow of epileptiform activity in benign epilepsy with centrotemporal spikes (BECTS) during ictal epileptiform...
-
Phoenixin-14 reduces the frequency of interictal-like events in mice brain slices
Phoenixin-14 (PNX-14) has a wide bioactivity in the central nervous system. Its role in the hypothalamus has been investigated, and it has been...
-
Blood T cells and Cytokine Levels During Interictal-Ictal Transitions
It is largely unknown how and why acute epileptic seizures develop in a brain that does not seize most of the time. Not only local neuroinflammation...
-
Propagation of Endogenous Electric Fields as a Possible Mechanism of Synchronization of Interictal Spikes in the Rat Neocortex
The effects of weak electric fields with parameters close to those of the electrical activity of brain structures on neural networks in the brain...
-
Extracting the Invisible: Mesial Temporal Source Detection in Simultaneous EEG and SEEG Recordings
Epileptic source detection relies mainly on visual expertise of scalp EEG signals, but it is recognised that epileptic discharges can escape to this...
-
Subclinical epileptiform discharges in Alzheimer’s disease are associated with increased hippocampal blood flow
BackgroundIn epilepsy, the ictal phase leads to cerebral hyperperfusion while hypoperfusion is present in the interictal phases. Patients with...
-
The Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy
Persons with pharmacoresistant epilepsy have a higher risk of mortality than those with controlled seizures. Seizure control can be achieved with...
-
Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method
BackgroundEpileptic seizures are an established comorbidity of Alzheimer’s disease (AD). Subclinical epileptiform activity (SEA) as detected by 24-h...
-
Effects of levetiracetam and oxcarbazepine monotherapy on intellectual and cognitive development in children with benign epilepsy with centrotemporal spikes
Levetiracetam (LEV) and oxcarbazepine (OXC) are commonly used in the treatment of epilepsy, but their efficacy and safety have seldom been compared...
-
Sleep and Epilepsy
In people with epilepsy, sleep may be disrupted by nocturnal epileptic activity as well as by the use of antiseizure medications (ASM). Conversely...
-
Synchronization Through Excitatory Synapses: Epilepsy but Also Conscious Perception
In this chapter we shall argue for a notion that will strike many as paradoxical, even absurd: we shall argue that neuronal circuitry allowing...
-
Variability of Single Pulse Electrical Stimulation Responses Recorded with Intracranial Electroencephalography in Epileptic Patients
Cohort studies of brain stimulations performed with stereo-electroencephalographic (SEEG) electrodes in epileptic patients allow to derive large...
-
Pathological and Physiological High-frequency Oscillations on Electroencephalography in Patients with Epilepsy
High-frequency oscillations (HFOs) encompass ripples (80 Hz–200 Hz) and fast ripples (200 Hz–600 Hz), serving as a promising biomarker for localizing...
-
Protection by Nano-Encapsulated Bacoside A and Bacopaside I in Seizure Alleviation and Improvement in Sleep- In Vitro and In Vivo Evidences
Therapeutic options to contain seizures, a transitional stage of many neuropathologies, are limited due to the blood–brain barrier (BBB). Herbal...
