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Brain Immune Cell Infiltration and Serum Metabolomic Characteristics Reveal that Lauric Acid Promotes Immune Cell Infiltration in Brain and Streptococcus suis Meningitis in Mice
Although naturally Streptococcus suis serotype 2 (SS2) causes meningitis resulting in death or sequela of neurological symptoms in pigs and humans,...
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DCLK1 is Overexpressed and Associated with Immune Cell Infiltration in Hepatocellular Carcinoma
Recent research has shown that Doublecortin-like kinase 1 (DCLK1) is overexpressed in different types of cancer. It has recently been described as a...
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Identification of Immune Infiltration and Iron Metabolism–Related Subgroups in Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with a broad spectrum of symptoms and prognoses. Effective therapy requires...
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HK3 stimulates immune cell infiltration to promote glioma deterioration
BackgroundGlioma is the most common and lethal type of brain tumor, and it is characterized by unfavorable prognosis and high recurrence rates. The...
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Tumorigenic role of Pak4 in ovarian cancer and its correlation with immune infiltration
BackgroundOvarian cancer is the most common cause of gynecological cancer death. Pak4 has been proved to be tumorigenic in many types of cancers, but...
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Upregulation of CENPM promotes breast carcinogenesis by altering immune infiltration
BackgroundThe involvement of centromere protein M (CENPM) in various types of cancer has been established, however, its impact on breast cancer and...
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cGAS-STING pathway expression correlates with genomic instability and immune cell infiltration in breast cancer
Genomic instability, as caused by oncogene-induced replication stress, can lead to the activation of inflammatory signaling, involving the cGAS-STING...
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Hub gene identification and immune infiltration analysis in hepatocellular carcinoma: Computational approach
In the case of hepatocellular carcinoma, there is a need to find novel immune biomarkers to predict cancer prognosis, which will help prolong patient...
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Immune cell infiltration and inflammatory landscape in primary brain tumours
BackgroundPrimary malignant brain tumours are more than one-third of all brain tumours and despite the molecular investigation to identify cancer...
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PSMC6 induces immune cell infiltration and inflammatory response to aggravate primary Sjögren’s syndrome
Increasing evidence suggests that immune cell infiltration is involved in primary Sjögren’s syndrome (pSS), while the underlying molecular mechanisms...
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Influence of SLC40A1 on Cytokine Interactions and Immune Infiltration in Glioblastoma
Numerous studies have explored the various functions of Slc40a1 in cancer development. However, the role of Slc40a1 in primary glioblastoma requires...
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Prognostic Value of CXCR6 and the Correlation with Immune Infiltration in the Microenvironment of Skin Cutaneous Melanoma
Increasing evidence has demonstrated that CXCRs are associated with the tumor infiltration of immune cells and regulate the tumor immune response....
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Potential diagnostic biomarkers: 6 cuproptosis- and ferroptosis-related genes linking immune infiltration in acute myocardial infarction
The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack specificity and exist as false positives in other non-cardiac...
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Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma
BackgroundLow grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify...
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Screening of Genes Associated with Immune Infiltration of Discoid Lupus Erythematosus Based on Weighted Gene Co-expression Network Analysis
Discoid lupus erythematosus (DLE) is a disorder of the immune system commonly seen in women of childbearing age. The pathophysiology and aetiology...
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Establishment and validation of an immune infiltration predictive model for ovarian cancer
BackgroundThe most prevalent mutation in ovarian cancer is the TP53 mutation, which impacts the development and prognosis of the disease. We looked...
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Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity
BackgroundThyroid cancer (THCA) has become increasingly common in recent decades, and women are three to four times more likely to develop it than...
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Comprehensive analysis of the expression, prognostic, and immune infiltration for COL4s in stomach adenocarcinoma
BackgroundCollagen (COL) genes, play a key role in tumor invasion and metastasis, are involved in tumor extracellular matrix (ECM)-receptor...
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Upregulation of TTK expression is associated with poor prognosis and immune infiltration in endometrial cancer patients
BackgroundThreonine and tyrosine kinase (TTK) is associated with invasion and metastasis in various tumors. However, the prognostic importance of TTK...
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Identification of Key lncRNAs Associated with Immune Infiltration and Prognosis in Gastric Cancer
Long non-coding RNAs (lncRNAs), as promising novel biomarkers for cancer treatment and prognosis, can function as tumor suppressors and oncogenes in...