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  1. Brain Immune Cell Infiltration and Serum Metabolomic Characteristics Reveal that Lauric Acid Promotes Immune Cell Infiltration in Brain and Streptococcus suis Meningitis in Mice

    Although naturally Streptococcus suis serotype 2 (SS2) causes meningitis resulting in death or sequela of neurological symptoms in pigs and humans,...

    Xuan Jiang, Fengyang Li, ... Liancheng Lei in Molecular Neurobiology
    Article 16 April 2024
  2. DCLK1 is Overexpressed and Associated with Immune Cell Infiltration in Hepatocellular Carcinoma

    Recent research has shown that Doublecortin-like kinase 1 (DCLK1) is overexpressed in different types of cancer. It has recently been described as a...

    Juan Manuel Velázquez-Enríquez, Renata Cerna, ... Verónica Rocío Vásquez-Garzón in Biochemical Genetics
    Article 31 January 2024
  3. Identification of Immune Infiltration and Iron Metabolism–Related Subgroups in Autism Spectrum Disorder

    Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with a broad spectrum of symptoms and prognoses. Effective therapy requires...

    Wenyan Huang, Zhenni Liu, ... Wanghong Zhao in Journal of Molecular Neuroscience
    Article 18 January 2024
  4. HK3 stimulates immune cell infiltration to promote glioma deterioration

    Background

    Glioma is the most common and lethal type of brain tumor, and it is characterized by unfavorable prognosis and high recurrence rates. The...

    Shupeng Li, Ziwei Li, ... **quan Cai in Cancer Cell International
    Article Open access 01 October 2023
  5. Tumorigenic role of Pak4 in ovarian cancer and its correlation with immune infiltration

    Background

    Ovarian cancer is the most common cause of gynecological cancer death. Pak4 has been proved to be tumorigenic in many types of cancers, but...

    Lan Tang, Hong Ye, ... Lan Yu in BMC Medical Genomics
    Article Open access 28 May 2024
  6. Upregulation of CENPM promotes breast carcinogenesis by altering immune infiltration

    Background

    The involvement of centromere protein M (CENPM) in various types of cancer has been established, however, its impact on breast cancer and...

    Yanchu Tong, Tongzhou Zhou, ... Lu Qin in BMC Cancer
    Article Open access 10 January 2024
  7. cGAS-STING pathway expression correlates with genomic instability and immune cell infiltration in breast cancer

    Genomic instability, as caused by oncogene-induced replication stress, can lead to the activation of inflammatory signaling, involving the cGAS-STING...

    Mengting Chen, Shibo Yu, ... Marcel A. T. M. van Vugt in npj Breast Cancer
    Article Open access 02 January 2024
  8. Hub gene identification and immune infiltration analysis in hepatocellular carcinoma: Computational approach

    In the case of hepatocellular carcinoma, there is a need to find novel immune biomarkers to predict cancer prognosis, which will help prolong patient...

    Swetha Pulakuntla, Shri Abhiav Singh, Vaddi Damodara Reddy in In Silico Pharmacology
    Article 06 May 2024
  9. Immune cell infiltration and inflammatory landscape in primary brain tumours

    Background

    Primary malignant brain tumours are more than one-third of all brain tumours and despite the molecular investigation to identify cancer...

    Amalia Luce, Marianna Abate, ... Michele Caraglia in Journal of Translational Medicine
    Article Open access 30 May 2024
  10. PSMC6 induces immune cell infiltration and inflammatory response to aggravate primary Sjögren’s syndrome

    Increasing evidence suggests that immune cell infiltration is involved in primary Sjögren’s syndrome (pSS), while the underlying molecular mechanisms...

    Yongzhu Piao, Yutong Qi, ... Qingnan Liu in Journal of Human Genetics
    Article 04 January 2023
  11. Influence of SLC40A1 on Cytokine Interactions and Immune Infiltration in Glioblastoma

    Numerous studies have explored the various functions of Slc40a1 in cancer development. However, the role of Slc40a1 in primary glioblastoma requires...

    Jiahao Jiang, Riquan Duan, ... Chun Luo in NeuroMolecular Medicine
    Article 16 May 2024
  12. Prognostic Value of CXCR6 and the Correlation with Immune Infiltration in the Microenvironment of Skin Cutaneous Melanoma

    Increasing evidence has demonstrated that CXCRs are associated with the tumor infiltration of immune cells and regulate the tumor immune response....

    Guiqing Ding, Tong Zhang, ... **aodong Cheng in Biochemical Genetics
    Article 25 January 2024
  13. Potential diagnostic biomarkers: 6 cuproptosis- and ferroptosis-related genes linking immune infiltration in acute myocardial infarction

    The current diagnostic biomarkers of acute myocardial infarction (AMI), troponins, lack specificity and exist as false positives in other non-cardiac...

    Mengdan Miao, Shanhu Cao, ... Mingqi Zheng in Genes & Immunity
    Article Open access 08 July 2023
  14. Construction and validation of an immune infiltration-related risk model for predicting prognosis and immunotherapy response in low grade glioma

    Background

    Low grade glioma (LGG) is considered a heterogeneous tumor with highly variable survival and limited efficacy of immunotherapy. To identify...

    **na Li, Qing Guo, Rui **ng in BMC Cancer
    Article Open access 05 August 2023
  15. Screening of Genes Associated with Immune Infiltration of Discoid Lupus Erythematosus Based on Weighted Gene Co-expression Network Analysis

    Discoid lupus erythematosus (DLE) is a disorder of the immune system commonly seen in women of childbearing age. The pathophysiology and aetiology...

    Yuru Han, Shuang Liu, ... Xuefeng Gu in Biochemical Genetics
    Article 07 March 2024
  16. Establishment and validation of an immune infiltration predictive model for ovarian cancer

    Background

    The most prevalent mutation in ovarian cancer is the TP53 mutation, which impacts the development and prognosis of the disease. We looked...

    Zhenxia Song, **gwen Zhang, ... **aoning Liu in BMC Medical Genomics
    Article Open access 28 September 2023
  17. Estrogen-related genes for thyroid cancer prognosis, immune infiltration, staging, and drug sensitivity

    Background

    Thyroid cancer (THCA) has become increasingly common in recent decades, and women are three to four times more likely to develop it than...

    Leiying Zhang, Man Zhou, ... **angtai Zeng in BMC Cancer
    Article Open access 31 October 2023
  18. Comprehensive analysis of the expression, prognostic, and immune infiltration for COL4s in stomach adenocarcinoma

    Background

    Collagen (COL) genes, play a key role in tumor invasion and metastasis, are involved in tumor extracellular matrix (ECM)-receptor...

    Ying Xu, Hangbin **, ... Yu Wang in BMC Medical Genomics
    Article Open access 21 June 2024
  19. Upregulation of TTK expression is associated with poor prognosis and immune infiltration in endometrial cancer patients

    Background

    Threonine and tyrosine kinase (TTK) is associated with invasion and metastasis in various tumors. However, the prognostic importance of TTK...

    Hongxiang Du, Li Zhang, ... **aoqing Yang in Cancer Cell International
    Article Open access 09 January 2024
  20. Identification of Key lncRNAs Associated with Immune Infiltration and Prognosis in Gastric Cancer

    Long non-coding RNAs (lncRNAs), as promising novel biomarkers for cancer treatment and prognosis, can function as tumor suppressors and oncogenes in...

    Wen **, Jianchao Jia, ... Lan Yu in Biochemical Genetics
    Article 24 April 2024
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