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Genetics of Sex Differences in Immunity
Women have a stronger immune response and a higher frequency of most autoimmune diseases than men. While much of the difference between men and women...
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Royal jelly and its hormonal effects in breast cancer: a literature review
BackgroundBreast cancer is the most common cancer in women which can be cured in most individuals with early-stage non-metastatic disease. Imbalance...
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Sex, hormones and cerebrovascular function: from development to disorder
Proper cerebrovascular development and neurogliovascular unit assembly are essential for brain growth and function throughout life, ensuring the...
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Differential Regulation of Mouse Hippocampal Gene Expression Sex Differences by Chromosomal Content and Gonadal Sex
Common neurological disorders, like Alzheimer’s disease (AD), multiple sclerosis (MS), and autism, display profound sex differences in prevalence and...
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Natural and Experimental Sex Reversal in Birds and Other Groups of Vertebrates, with the Exception of Mammals
AbstractThe review is focused on the current problem of sex determination. Many research papers were devoted to this issue, but all the details of...
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The conne**on between sex and immune responses
There are notable sex-based differences in immune responses to pathogens and self-antigens, with female individuals exhibiting increased...
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Sex-Gender-Based Differences in Metabolic Diseases
Sexual dimorphism creates different biological and cellular activities and selective regulation mechanisms in males and females, thus generating...
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Sex-specific differences in zebrafish brains
In this systematic review, we highlight the differences between the male and female zebrafish brains to understand their differentiation and their...
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Cycle-dependent sex differences in expression of membrane proteins involved in cerebrospinal fluid secretion at rat choroid plexus
BackgroundFemale sex is a known risk factor of brain disorders with raised intracranial pressure (ICP) and sex hormones have been suggested to alter...
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Conserved genes regulating human sex differentiation, gametogenesis and fertilization
The study of the functional genome in mice and humans has been instrumental for describing the conserved molecular mechanisms regulating human...
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The Level of Sex Hormones and Corticosterone in Female Rats during Modeling of Visceral Obesity, Subsequent Physical Activity, and Normalization of the Diet
The effects of diet-induced visceral obesity and non-drug options of its correction on the level of sex hormones and corticosterone were evaluated in...
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Modeling brain sex in the limbic system as phenotype for female-prevalent mental disorders
BackgroundSex differences exist in the prevalence and clinical manifestation of several mental disorders, suggesting that sex-specific brain...
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The influence of sex and reproductive cycle on cocaine-induced behavioral and neurobiological alterations: a review
This systematic review (SR) was aimed at answering two questions: (1) how sex and ovarian hormones alter behavior associated with cocaine use; (2)...
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Sex and Gender Differences in Tuberculosis Pathogenesis and Treatment Outcomes
Tuberculosis remains a daunting public health concern in many countries of the world. A consistent observation in the global epidemiology of...
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Considerations and challenges for sex-aware drug repurposing
Sex differences are essential factors in disease etiology and manifestation in many diseases such as cardiovascular disease, cancer, and...
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Training in the implementation of sex and gender research policies: an evaluation of publicly available online courses
BackgroundRecently implemented research policies requiring the inclusion of females and males have created an urgent need for effective training in...
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Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals
BackgroundMammalian gonadal sex is determined by the presence or absence of a Y chromosome and the subsequent production of sex hormones contributes...
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Alzheimer’s disease-related transcriptional sex differences in myeloid cells
Sex differences have been identified in many diseases associated with dysregulated immune responses, including Alzheimer’s disease (AD), for which...
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Sex-specific morphs: the genetics and evolution of intra-sexual variation
Sex-specific morphs exhibit discrete phenotypes, often including many disparate traits, that are observed in only one sex. These morphs have evolved...
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Sex-specific neurobehavioral and biochemical effects of developmental exposure to Malathion in offspring mice
Malathion is an organophosphate pesticide (OP) commonly used in agriculture, industry, and veterinary medicine. Sex is a crucial factor in responding...
