Search
Search Results
-
Prenylated Flavanone Isolated from Dalea Species as a Potential Multitarget-Neuroprotector in an In Vitro Alzheimer’s Disease Mice Model
Alzheimer’s disease (AD) involves a neurodegenerative process that has not yet been prevented, reversed, or stopped. Continuing with the search for...
-
Microbial production of the plant flavanone hesperetin from caffeic acid
ObjectiveHesperetin is an important O -methylated flavonoid produced by citrus fruits and of potential pharmaceutical relevance. The microbial...
-
Bioactivity-boosting strategy based on combination of anti-allergic O-methylated catechin with a Citrus flavanone, hesperetin
Many patients with allergies have anxiety about taking anti-allergic medicines due to their side effects and increased medical expenses. Thus,...
-
Retraction Note: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s40360-019-0335-5.
-
A mechanistic review of the pharmacological potential of narirutin: a dietary flavonoid
Flavanones, a type of polyphenol, are found in substantial amounts in citrus fruits. When high- or moderate-dose orange juice consumption occurs,...
-
Anti-influenza A virus activity of flavonoids in vitro: a structure–activity relationship
Secondary plant metabolites from food extracts, namely daidzein, quercetin, and luteolin, exhibit anti-influenza virus effects, with IC 50 values of...
-
Evaluation of chemical constituents of Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) as adenosine A1/A2A receptor ligands
Rooibos ( Aspalathus linearis ) and Honeybush ( Cyclopia intermedia ) are popular tisanes in South Africa and are of growing interest due to the wide...
-
RETRACTED ARTICLE: Anti-hyperalgesic properties of a flavanone derivative Poncirin in acute and chronic inflammatory pain models in mice
BackgroundPoncirin is flavanone derivative (isolated from Poncirus trifoliata ) with known pharmacological activities such as anti-tumor,...
-
Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats
Carbon monoxide (CO) is produced via incomplete combustion of fossil fuels and it may cause long-term neurological sequel upon exposure. Hesperidin...
-
Comprehensive overview of how to fade into succinate dehydrogenase dysregulation in cancer cells by naringenin-loaded chitosan nanoparticles
Mitochondrial respiration complexes play a crucial function. As a result, dysfunction or change is intimately associated with many different...
-
Aromatase inhibitors isolated from a flowering tea, snow Chrysanthemum (the capitula of Coreopsis tinctoria Nutt.)
Methanol extract from the capitula of Coreopsis tinctoria Nutt. (Asteraceae), which is also known as a flowering tea or blooming tea “Snow Chrysanthemum...
-
Aerobic glycolysis in colon cancer is repressed by naringin via the HIF1A pathway
Metabolic reprogramming is a common phenomenon in cancer, with aerobic glycolysis being one of its important characteristics. Hypoxia-inducible...
-
In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo–keto reductases
The most important dose-limiting factor of the anthracycline idarubicin is the high risk of cardiotoxicity, in which the secondary alcohol metabolite...
-
HPLC–ESI–QTOF–MS/MS profiling and therapeutic effects of Schinus terebinthifolius and Schinus molle fruits: investigation of their antioxidant, antidiabetic, anti-inflammatory and antinociceptive properties
The aim of the current work was to study the phytochemical variability among Schinus terebinthifolius (STE) and Schinus molle (SME) fruit extracts....
-
Maclura tinctoria (L.) D. Don ex Steud. (Moraceae): a review of the advances in ethnobotanical knowledge, phytochemical composition, and pharmacological potential
Maclura tinctoria (Moraceae), commonly known as dinde, is a lactescent tree of significant economic importance with extensive ethnomedicinal and...
-
The Chemistry and Pharmacology of Mandarin Orange (Citrus reticulata)
Citrus fruits and their juices are among the most widely consumed fruit products as a regular source of nutrition, flavor, and health remedy. In...
-
Bioprospecting and Evolutionary Significance of Photoprotectors in Non-flowering Lower Plants
Environmental change as well as the continued increase in UV radiation (UVR; 280–400 nm) has a significant impact on terrestrial and aquatic...
-
Multifaceted roles of flavonoids mediating plant-microbe interactions
Plant-microbe interactions dynamically affect plant growth, health, and development. The mechanisms underpinning these associations are—to a large...
-
The citrus flavanone naringenin attenuates zymosan-induced mouse joint inflammation: induction of Nrf2 expression in recruited CD45+ hematopoietic cells
BackgroundNaringenin is a biologically active analgesic, anti-inflammatory, and antioxidant flavonoid. Naringenin targets in inflammation-induced...
-
Flavonoid-Based Derivatives for Modulating Various Targets of Alzheimer’s Disease
Alzheimer’s disease (AD), an advanced multifactorial neurodegenerative disease mainly accompanied by cognitive impairment, is the most conversant...