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Biomedicine

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Showing 1-20 of 59 results

  1. Cancer and Hypercalcemia

    Alterations of calcium homeostasis leading to hypercalcemia can occur at three different levels: the bone (increased osteoclast activity), kidney...
    Franco Lumachi, Stefano M. M. Basso in Handbook of Cancer and Immunology
    Living reference work entry 2023

  2. The importance of kidney calcium handling in the homeostasis of extracellular fluid calcium

    Extracellular fluid calcium concentration must be maintained within a narrow range in order to sustain many biological functions, encompassing muscle...

    Caroline Prot-Bertoye, Loïc Lievre, Pascal Houillier in Pflügers Archiv - European Journal of Physiology
    Article 16 July 2022

  3. Metabolic Causes of Tremor

    Metabolic causes of tremor include systemic metabolic, neurometabolic, and endocrine abnormalities. These can be diagnosed by identification of...
    Diksha Mohanty, Peter Hedera in Mechanisms and Emerging Therapies in Tremor Disorders
    Chapter 2023

  4. Primary Hyperparathyroidism Secondary to Ectopic Parathyroid Adenoma: A Case Report

    Primary hyperparathyroidism (PHPT) secondary to parathyroid gland adenoma is mildly symptomatic and thus often incidentally diagnosed. In this...
    Agata Walulik, Weronika Misiąg, ... Mariusz Chabowski in Invasive Diagnostics and Therapy
    Chapter 2021

  5. Ca2+-Sensing Receptor (CaSR)

    Giovanna Valenti in Encyclopedia of Molecular Pharmacology
    Reference work entry 2021

  6. Ca2+-Sensing Receptor (CaSR)

    Giovanna Valenti in Encyclopedia of Molecular Pharmacology
    Living reference work entry 2021

  7. Clinical diagnosis of genetic disorders at both single-nucleotide and chromosomal levels based on BGISEQ-500 platform

    Most variations in the human genome refer to single-nucleotide variation (SNV), small fragment insertions and deletions, and genomic copy number...

    Yanqiu Liu, Liangwei Mao, ... **aoming Wei in Human Genome Variation
    Article Open access 22 May 2023

  8. Genetics of Skeletal Disorders

    Bone and mineral diseases encompass a variety of conditions that involve altered skeletal homeostasis and are frequently associated with changes in...
    Fadil M. Hannan, Paul J. Newey, ... Rajesh V. Thakker in Bone Regulators and Osteoporosis Therapy
    Chapter 2020

  9. Pharmacodynamic Evaluation: Endocrinology

    In this chapter, pharmacodynamic evaluations for the most common clinical endocrine disorders are discussed. Special attention is given to new...
    Michael A. B. Naafs in Drug Discovery and Evaluation: Methods in Clinical Pharmacology
    Reference work entry 2020

  10. Metabolic Disturbance

    As specific cancer treatments evolved, our ability to anticipate side effects and prevent them has also been refined. Prophylaxis allows us to avoid...
    Pamela Carvalho Muniz, Mayndra Mychelle Landgraf, ... Michelle Samora de Almeida in International Manual of Oncology Practice
    Chapter 2019

  12. Animal Models of Phosphorus Homeostasis

    Purpose of Review

    Phosphate homeostasis is a complex process that involves many regulators and multiple organs. In vivo models have been used...

    Laurent Beck, Despina Sitara in Current Molecular Biology Reports
    Article 25 January 2019

  14. Diagnosis of Osteosarcopenia – Biochemistry and Pathology

    Sarcopenia and osteopenia/osteoporosis are two frequent conditions that often coexist amongst frail, older adults. Individuals affected from both...
    Barbara Obermayer-Pietsch, Markus Herrmann in Osteosarcopenia: Bone, Muscle and Fat Interactions
    Chapter 2019

  15. Large intragenic deletion of CDC73 (exons 4–10) in a three-generation hyperparathyroidism-jaw tumor (HPT-JT) syndrome family

    Background

    Inactivating mutations of CDC73 cause Hyperparathyroidism-Jaw Tumour syndrome (HPT-JT), Familial Isolated Hyperparathyroidism (FIHP) and...

    Vito Guarnieri, Raewyn M. Seaberg, ... David E. C. Cole in BMC Medical Genetics
    Article Open access 03 August 2017

  16. Calcium Sensing Receptor (CASR)

    Rakshya Gorkhali, **aojuan Tan, Jenny J. Yang in Encyclopedia of Signaling Molecules
    Reference work entry 2018

  17. Association of calcium sensing receptor polymorphisms at rs1801725 with circulating calcium in breast cancer patients

    Background

    Breast cancer (BC) patients with late-stage and/or rapidly growing tumors are prone to develop high serum calcium levels which have been...

    Li Wang, Sarrah E. Widatalla, ... Amos M. Sakwe in BMC Cancer
    Article Open access 02 August 2017

  18. Pharmacodynamic Evaluation: Endocrinology

    In this chapter, pharmacodynamic evaluations for the most common clinical endocrine disorders are discussed. Special attention is given to new...
    Michael A. B. Naafs in Drug Discovery and Evaluation: Methods in Clinical Pharmacology
    Living reference work entry 2017

  19. Calcium Sensing Receptor (CASR)

    Rakshya Gorkhali, **aojuan Tan, Jenny J. Yang in Encyclopedia of Signaling Molecules
    Living reference work entry 2017

  20. G Protein-Coupled Receptor Mutations and Human Genetic Disease

    Genetic variations in G protein-coupled receptor genes (GPCRs) disrupt GPCR function in a wide variety of human genetic diseases. In vitro strategies...
    Miles D. Thompson, Geoffrey N. Hendy, ... David E. C. Cole in Pharmacogenomics in Drug Discovery and Development
    Protocol 2014
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