Search
Search Results
-
Switching Off Vascular MAPK Signaling: A Novel Strategy to Prevent Delayed Cerebral Ischemia Following Subarachnoid Hemorrhage
Patients who initially survive the rupture and repair of a brain aneurysm often take a devastating turn for the worse some days later and die or...
-
Early Differential Diagnosis and Restorative Treatment of Patients with Cerebral Palsy
This article addresses an urgent problem – the early diagnosis and comprehensive rehabilitation therapy of patients with cerebral palsy (CP). The...
-
A cost-effectiveness analysis of early detection and bundled treatment of postpartum hemorrhage alongside the E-MOTIVE trial
Timely detection and treatment of postpartum hemorrhage (PPH) are crucial to prevent complications or death. A calibrated blood-collection drape can...
-
Clinical score for early diagnosis and treatment of stroke-like episodes in MELAS syndrome
Background and objectivesStroke-like episodes (SLEs) in patients with MELAS syndrome are often initially misdiagnosed as acute ischemic stroke (AIS),...
-
Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of disease
BackgroundIntra-ductal cancer (IDC) is the most common type of breast cancer, with intra-lobular cancer (ILC) coming in second. Surgery is the...
-
Treatment of Stroke at a Delayed Timepoint with a Repurposed Drug Targeting Sigma 1 Receptors
Sigma 1 receptors are intracellular chaperone proteins that have been explored as a subacute treatment to enhance post-stroke recovery. We recently...
-
Survival outcomes following treatment delays among patients with early-stage female cancers: a nationwide study
BackgroundThe coronavirus disease 2019 (COVID-19) severely hindered the timely receipt of health care for patients with cancer, especially female...
-
Similarities in the Electrographic Patterns of Delayed Cerebral Infarction and Brain Death After Aneurysmal and Traumatic Subarachnoid Hemorrhage
While subarachnoid hemorrhage is the second most common hemorrhagic stroke in epidemiologic studies, the recent DISCHARGE-1 trial has shown that in...
-
NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage
BackgroundThe NLRP3 inflammasome is a critical mediator of several vascular diseases through positive regulation of proinflammatory pathways. In this...
-
Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice
Cancer survivors may experience long-term cardiovascular complications due to chemotherapeutic drugs such as doxorubicin (DOX). The exact mechanism...
-
Organophosphorus poisoning induced delayed neurotoxicity: a report of two cases
IntroductionOrganophosphorus compounds (OPC) are one of the most commonly used pesticides worldwide and are often misused for suicidal poisoning due...
-
Association of delayed chemoradiotherapy with elevated Epstein-Barr virus DNA load and adverse clinical outcome in nasopharyngeal carcinoma treatment during the COVID-19 pandemic: a retrospective study
Background:To summarize the impact of radiotherapy (RT) and chemotherapy delays on patients with nasopharyngeal carcinoma (NPC) during the COVID-19...
-
Delayed diagnosis of mild mucopolysaccharidosis type IVA
BackgroundMucopolysaccharidosis IVA (MPS IVA) is a lysosomal storage disease caused by biallelic variants in the N-acetylgalactosamine-6-sulfatase ( GALNS...
-
Strategies of Early Diagnosis of Cancers
When cancer is identified early, the chances of survival improve. However, almost half of all malignancies are identified at an advanced stage. Early...
-
Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice
BackgroundIschemic stroke immediately evokes a strong neuro-inflammatory response within the vascular compartment, which contributes to primary...
-
Prophylactic Treatment of ASD Based on Sleep-Wake Circadian Rhythm Formation in Infancy to Early Childhood
The pathogenesis underlying autism spectrum disorder (ASD) and the causes of rapid increase of ASD patients remain unclear. However, recent reports...
-
Kinetics of glucose-6-phosphate dehydrogenase (G6PD) activity during Plasmodium vivax infection: implications for early radical malaria treatment
BackgroundPlasmodium vivax relapses due to dormant liver hypnozoites can be prevented with primaquine. However, the dose must be adjusted in...
-
Drug-Coated Balloon Treatment for Delayed Recanalization of Symptomatic Intracranial Artery Occlusion
Patients with medically refractory non-acute intracranial artery occlusion (ICAO) are difficult to treat. The optimal intervention for these patients...
-
Updates and confounding factors in delayed sleep–wake phase disorder
Delayed sleep–wake phase disorder (DSWPD) is a circadian rhythm sleep disorder characterised by a delay in the main sleep period, with patients...
-
Delayed spinal arachnoiditis with syringomyelia following aneurysmal subarachnoid haemorrhage: a case report with patient experience
Background and importanceSyringomyelia, or the formation of fluid-filled cysts within the spinal cord, associated with delayed spinal arachnoiditis...
