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Nanobiosensing Platforms for Early Detection of Cancer
Cancer remains the leading cause of death worldwide, with an estimated 18.1 million cancer cases in 2020 alone. The societal and financial burden of...
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Early Cancer Detection: Challenges and Opportunities
Cancer is the second leading cause of death both globally and in the United States [1]. Recent studies suggest that the detection of cancer at early,...
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Nanomaterial-Driven Advancements in Early Cancer Detection
Due to the complex and multifactorial nature of cancer, efforts to find a universal cure have shown limited success. Recognizing the crucial...
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Exosome Detection for Early Cancer Diagnosis
Exosomes are small extracellular vesicles, with a size of 100 nm or less, composed of lipid bilayers. These vesicles are released by cells and...
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The role of biomarkers in the early detection of pancreatic cancer
Pancreatic surveillance can detect early-stage pancreatic cancer and achieve long-term survival, but currently involves annual endoscopic ultrasound...
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Skin Cancer: Prevention and Early Detection
Melanoma and non-melanoma skin cancers are one of the most common cancers prevalent in white-skinned populations, and its rising incidence and...
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Utilizing nullomers in cell-free RNA for early cancer detection
Early detection of cancer can significantly improve patient outcomes; however, sensitive and highly specific biomarkers for cancer detection are...
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Liquid biopsies: the future of cancer early detection
Cancer is a worldwide pandemic. The burden it imposes grows steadily on a global scale causing emotional, physical, and financial strains on...
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Cancer signature ensemble integrating cfDNA methylation, copy number, and fragmentation facilitates multi-cancer early detection
Cell-free DNA (cfDNA) sequencing has demonstrated great potential for early cancer detection. However, most large-scale studies have focused only on...
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Tumor Markers in Early Detection and Monitoring of Prostate Cancer: Recent Advances
Due to the fact that the use of prostate-specific antigen (PSA) in prostate cancer (PC) management is limited, the search for novel biomarkers useful...
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Autoantibodies, antigen-autoantibody complexes and antigens complement CA125 for early detection of ovarian cancer
BackgroundMultiple antigens, autoantibodies (AAb), and antigen-autoantibody (Ag-AAb) complexes were compared for their ability to complement CA125...
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Emerging Biohybrids of Aptamer-Based Nano-Biosensing Technologies for Effective Early Cancer Detection
Cancer is a leading global cause of mortality, which underscores the imperative of early detection for improved patient outcomes. Biorecognition...
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REPRESENT recommendations: improving inclusion and trust in cancer early detection research
Detecting cancer early is essential to improving cancer outcomes. Minoritized groups remain underrepresented in early detection cancer research,...
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Minimally invasive approaches for the early detection of endometrial cancer
Endometrial cancer (EC) is one of the most common gynecologic cancers and its incidence is rising globally. Although advanced EC has a poor...
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Evaluating multi-cancer early detection tests: an argument for the outcome of recurrence-updated stage
The advent of multi-cancer early detection (MCED) tests has the potential to revolutionise the diagnosis of cancer, improving patient outcomes...
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Modelled mortality benefits of multi-cancer early detection screening in England
BackgroundScreening programmes utilising blood-based multi-cancer early detection (MCED) tests, which can detect a shared cancer signal from any site...
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Prospective implementation of AI-assisted screen reading to improve early detection of breast cancer
Artificial intelligence (AI) has the potential to improve breast cancer screening; however, prospective evidence of the safe implementation of AI...
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Increased blood draws for ultrasensitive ctDNA and CTCs detection in early breast cancer patients
Early breast cancer patients often experience relapse due to residual disease after treatment. Liquid biopsy is a methodology capable of detecting...
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Multi-dimensional cell-free DNA-based liquid biopsy for sensitive early detection of gastric cancer
BackgroundGastric cancer is the fifth most common cancer type. Most patients are diagnosed at advanced stages with poor prognosis. A non-invasive...
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Early detection of pancreatic cancer by liquid biopsy “PANLIPSY”: a french nation-wide study project
BackgroundPancreatic cancer, predominantly characterized by ductal adenocarcinoma (PDAC) accounts for 90% of cases and is the fourth leading cause of...
