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1. Drug Release

   Drug release from dosage forms (also termed drug liberation) is a prerequisite for absorption to occur: only free molecules in solution can cross...

   Alan Talevi, María E. Ruiz in ADME Processes in Pharmaceutical Sciences

   Chapter 2024
   

2. Drug Solubilization and Drug Release from Polymeric Micelles

   Amphiphilic polymeric block copolymers find frequent applications due to their ability to deliver hydrophobic moieties to the physiological system....

   Ganesh Vambhurkar, Naitik Jain, ... Saurabh Srivastava in Polymeric Micelles: Principles, Perspectives and Practices

   Chapter 2023
   

3. Evaluation of Dose-Response Relationship of Permeation Enhancer Isopropyl Myristate Release on Drug Release: Release Enhancement Efficiency and Molecular Mechanism

   The objective of this study is to investigate the dose-response relationship between various concentrations of permeation enhancers (PEs) and their...

   Jiuheng Ruan, Sida Liao, ... Liang Fang in AAPS PharmSciTech

   Article 19 December 2023
   

4. Assessment of Temperature-Dependent Drug Release of Solubilizing Nanoformulations Using the SITUA

   The evaluation of temperature-dependent drug release for solubilizing nanoformulations uses a modification of the stable isotope ultrafiltration...

   Stephan T. Stern, Sarah L. Skoczen, Young Hwan Park in Characterization of Nanoparticles Intended for Drug Delivery

   Protocol 2024
   

5. Development of Drug Release Model for Suspensions in ESCAR (Emulator of SubCutaneous Absorption and Release)

   We recently developed an in vitro testing system, namely, ESCAR (Emulator of SubCutaneous Absorption and Release). The objective of this work was to...

   Hao Lou, Michael J. Hageman in The AAPS Journal

   Article 22 March 2023
   

6. Impact of Apparatus and Adapter on In vitro Drug Release of Ophthalmic Semisolid Drug Products

   Purpose

   In vitro release testing (IVRT) is a widely used tool for evaluating the quality and performance of drug products. However, standardized...

   Catheleeya Mekjaruskul, André O’Reilly Beringhs, ... **uling Lu in Pharmaceutical Research

   Article 07 September 2023
   

7. Green synthesis of anti-cancer drug-loaded gold nanoparticles for low-intensity pulsed ultrasound targeted drug release

   In the present work, we have designed a one-pot green protocol in which anti-cancer drugs (curcumin and doxorubicin) can be directly loaded on the...

   Anshuman Jakhmola, Tyler K. Hornsby, ... Jahangir (Jahan) Tavakkoli in Drug Delivery and Translational Research

   Article 19 January 2024
   

8. Drug Release from Surfactant-Containing Amorphous Solid Dispersions: Mechanism and Role of Surfactant in Release Enhancement

   Purpose

   To understand how surfactants affect drug release from ternary amorphous solid dispersions (ASDs), and to investigate different mechanisms of...

   Ruochen Yang, Geoff G. Z. Zhang, ... Lynne S. Taylor in Pharmaceutical Research

   Article 13 April 2023
   

9. Modified-Release Drug Delivery Systems

   An ideal drug delivery system would have two prerequisites. Firstly, it should require a single dose for the entire treatment period (e.g., days or...

   Saeed Ahmad Khan, Roohullah, Alam Zeb in Essentials of Industrial Pharmacy

   Chapter 2022
   

10. QBD Approach for Design and Characterization of Pramlintide Microspheres for Controlled Drug Release

    Purpose

    The research was centered on the optimization of the microsphere formulation through a systematic quality-by-design (QBD) methodology, as well...

    Lakshmikanth Reddy P, Sangeetha Shanmugasundaram in Journal of Pharmaceutical Innovation

    Article 23 November 2023
    

11. Quality-by-Design Based Development of Doxycycline Hyclate–Loaded Polymeric Microspheres for Prolonged Drug Release

    This study explores a novel approach to address the challenges of delivering highly water-soluble drug molecules by employing hydrophobic ion-pairing...

    Suraj Longre, Dhwani Rana, ... Derajram Benival in AAPS PharmSciTech

    Article 29 February 2024
    

12. Chitosan-Derived Nanocarrier Polymers for Drug Delivery and pH-Controlled Release in Type 2 Diabetes Treatment

    Diabetes, particularly Type 2 Diabetes Mellitus (T ₂ DM), is a chronic metabolic disorder with high and increasing global prevalence, characterized by...

    Shanshan Guo, Hua Li in Journal of Fluorescence

    Article 18 June 2024
    

13. Types of Polymeric Micelles for Controlled Drug Release

    Polymeric micelles are nano-sized drug delivery carrier systems with a core or shell structure composed of biocompatible and biodegradable...

    Divya Mahajan, Divya Suares, ... Saritha Shetty in Polymeric Micelles: Principles, Perspectives and Practices

    Chapter 2023
    

14. Mucoadhesive Films of Docetaxel with Ceramide as an Adjuvant Monitoring Polymer-Drug Partitioning for Optimal Drug Release

    Background

    Millions of individuals worldwide are affected by cancer, with increasing instances by 1% annually and strikingly high mortality rates of...

    Poornima Agrawal, Vandana Soni in Journal of Pharmaceutical Innovation

    Article 20 May 2023
    

15. Advancements in nanoscale delivery systems: optimizing intermolecular interactions for superior drug encapsulation and precision release

    Nanoscale preparations, such as nanoparticles, micelles, and liposomes, are increasingly recognized in pharmaceutical technology for their high...

    Enpeng Dong, Qingqing Huo, ... Dongfei Liu in Drug Delivery and Translational Research

    Article 04 April 2024
    

16. Drug Release

    Alan Talevi, María Esperanza Ruiz in The ADME Encyclopedia

    Reference work entry 2022
    

17. Development of an Accelerated Rotator-based Drug Release Method for the Evaluation of Bupivacaine Multivesicular Liposomes

    Purpose

    A multivesicular liposome (MVL) is a liposomal vehicle designed to achieve sustained release characteristics for drugs with short half-lives....

    Ziyun **a, Minzhi Yu, ... Anna Schwendeman in Pharmaceutical Research

    Article 11 January 2024
    

18. Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication

    Purpose

    The study aims to develop an interpenetrating polymer network (IPN) hydrogel bead. This drug carrier system with a hydrophilic polymer is...

    Kalaiarasan Sellamuthu, Sheela Angappan in Journal of Pharmaceutical Innovation

    Article 17 January 2024
    

19. Investigating the influence of ultrasound parameters on ibuprofen drug release from hydrogels

    Hydrogels are promising ultrasound-responsive drug delivery systems. In this study, we investigated how different ultrasound parameters affected drug...

    Svenja Meissner, Jhansi H. Akepogu, ... Sachin S. Thakur in Drug Delivery and Translational Research

    Article 12 December 2022
    

20. How Does Fluid Flow Influence Drug Release from Drug Filled Implants?

    Drug-filled implants (DFIs) have emerged as an innovative approach to control the delivery of drugs. These devices contain the drug within the...

    David King, Christopher McCormick, Sean McGinty in Pharmaceutical Research

    Article Open access 07 January 2022