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1. Effect of Sex on Structural and Morphological Parameters of Rat Heart under Conditions of Combined Exposure to Hypokinesia and Cold

   We studied the combined effect of hypokinesia and external cooling on structural and morphological changes in the ventricular myocardium and...

   V. P. Nuzhny, N. A. Kibler, ... D. N. Shmakov in Bulletin of Experimental Biology and Medicine

   Article 01 April 2022

2. Changes in Total Cholesterol and Heart Rate in Normotensive and Hypertensive Rats under Combined Influence of Cold Exposure and Hypokinesia

   We studied the effect of hypokinesia alone and in combination with cold exposure on HR and total cholesterol content in the blood serum of Wistar,...

   D. N. Shmakov, V. P. Nuzhny, ... S. N. Kharin in Bulletin of Experimental Biology and Medicine

   Article 24 October 2020

3. Features of α₂-Adrenergic Regulation of Isolated Rat Heart after Hypokinesia

   We studied the effect of the α ₂ -adrenergic receptor agonist clonidine hydrochloride (10 ^—9 -10 ^—6 M) on the isolated heart of adult rats after 30-day...

   M. I. Sungatullina, R. I. Zaripova, ... T. L. Zefirov in Bulletin of Experimental Biology and Medicine

   Article 01 December 2023

4. Combined Effects of Hypokinesia and Ambient Temperature on Heart Remodeling in Normotensive and Hypertensive Rats

   We studied the effect of hypokinesia combined with cold exposure on morphological parameters of the heart in Wistar-Kyoto rats and rats with...

   D. N. Shmakov, V. P. Nuzhny, N. A. Kibler in Bulletin of Experimental Biology and Medicine

   Article 26 October 2019

5. Indicators of LPO and Antioxidant Protection in Rats During Long-Term Restriction of Motor Activity

   This article presents a comprehensive study of the parameters of LPO (concentrations of malondialdehyde, diene conjugates, and intensity of...

   A. V. Elikov in Bulletin of Experimental Biology and Medicine

   Article 01 December 2023

6. Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging

   MOTS-c is a peptide encoded by the short open reading frame of the mitochondrial 12S rRNA gene. It is significantly expressed in response to stress...

   Wei Wan, Lieliang Zhang, ... Jun Ying in Journal of Translational Medicine

   Article Open access 20 January 2023
   

7. The Synergistic Effect Study of Lipopolysaccharide (LPS) and A53T-α-Synuclein: Intranasal LPS Exposure on the A53T-α-Synuclein Transgenic Mouse Model of Parkinson’s Disease

   Aging and interactions between genetic and environmental factors are believed to be involved the chronic development of Parkinson’s disease (PD)....

   Qing He, Shuzhen Zhang, ... Wei Chen in Molecular Neurobiology

   Article 17 February 2024
   

8. Cardiotoxicity After Synthetic Cathinone Use; Two Cases, A Case Series and Sco** Review

   The cardiotoxic effects of synthetic cathinones remain largely unknown. In this study, we present two cases, a case series and a sco** review, to...

   K. L. Groenewegen, F. M. J. Gresnigt, ... D. W. de Lange in Cardiovascular Toxicology

   Article Open access 27 February 2024
   

9. Drugs Acting on Autonomic Nervous System

   The autonomic nervous system is largely distributed throughout the body and controls the autonomic and visceral functions, which occur without...

   Moitreyee Chattopadhyay, Bhaskar Pal in Essentials of Pharmacodynamics and Drug Action

   Chapter 2024
   

10. Thermal Physiology in the USA: A 100-Year History of the Science and Its Scientists (1880–1980)

    Body temperature is critical to the function of virtually every physiological system, and it is often used as evidence of life. As such, it was one...

    Clark M. Blatteis, Suzanne M. Schneider in Thermal Physiology

    Chapter 2022
    

11. Translation from Preclinical Research to Clinical Trials: Transdermal Drug Delivery for Neurodegenerative and Mental Disorders

    Neurodegenerative diseases (NDs), particularly dementia, provide significant problems to worldwide healthcare systems. The development of therapeutic...

    Phuong-Trang Nguyen-Thi, Tuong Kha Vo, ... Giau Van Vo in Pharmaceutical Research

    Article 11 June 2024
    

12. Protective Role of Capsaicin in Neurological Disorders: An Overview

    Different pathological conditions that begin with slow and progressive deformations, cause irreversible affliction by producing loss of neurons and...

    Sakshi Tyagi, Nikhila Shekhar, Ajit Kumar Thakur in Neurochemical Research

    Article 12 February 2022
    

13. Cerebellotoxic Agents

    The cerebellum is particularly vulnerable to neurotoxic agents and poisoning. People of all ages can be affected by cerebellar damage due to...

    Mario U. Manto in Handbook of the Cerebellum and Cerebellar Disorders

    Reference work entry 2022
    

14. Targeting the endocannabinoid system: a predictive, preventive, and personalized medicine-directed approach to the management of brain pathologies

    Cannabis-inspired medical products are garnering increasing attention from the scientific community, general public, and health policy makers. A...

    Vamsi Reddy, Dayton Grogan, ... Kumar Vaibhav in EPMA Journal

    Article 15 April 2020
    

15. Cerebellotoxic Agents

    The cerebellum is particularly vulnerable to neurotoxic agents and poisoning. People of all ages can be affected by cerebellar damage due to...

    Mario U. Manto in Handbook of the Cerebellum and Cerebellar Disorders

    Living reference work entry 2021
    

16. mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity

    Rationale

    A role of group I metabotropic glutamate receptor 5 (mGlu5) in regulating spontaneous locomotion and psychostimulant-induced hyperactivity...

    Chia-Shan Wu, Christopher P. Jew, ... Hui-Chen Lu in Psychopharmacology

    Article 24 October 2019
    

17. Synergistic anticataleptic effect of imipramine and nicotine in a rotenone-induced rat model

    Rationale

    Some antidepressants have been previously found to produce anti-parkinsonian effect; nicotine was known to mitigate experimental neurotoxic...

    Ilya D. Ionov, Irina I. Pushinskaya, ... Larissa A. Shpilevaya in Psychopharmacology

    Article 08 May 2019
    

18. Basal Ganglia

    The basal ganglia are a group of closely connected cell masses, forming a more or less continuum, extending from the telencephalon to the midbrain...

    Hans J. ten Donkelaar, Bart van de Warrenburg, ... Akira Hori in Clinical Neuroanatomy

    Chapter 2020
    

19. Visuospatial Neglect - a Theory-Informed Overview of Current and Emerging Strategies and a Systematic Review on the Therapeutic Use of Non-invasive Brain Stimulation

    Visuospatial neglect constitutes a supramodal cognitive deficit characterized by reduction or loss of spatial awareness for the contralesional space....

    Paul Theo Zebhauser, Marine Vernet, ... Anna-Katharine Brem in Neuropsychology Review

    Article Open access 20 November 2019
    

20. Sitagliptin and Liraglutide Modulate L-dopa Effect and Attenuate Dyskinetic Movements in Rotenone-Lesioned Rats

    L-dopa is still considered as the gold standard therapy for Parkinson’s disease (PD); however, L-dopa-induced dyskinesia (LID) is a serious...

    Ghada A. Badawi, Mai A. Abd El Fattah, ... Moushira I. El Sayed in Neurotoxicity Research

    Article 23 January 2019