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Macrolide Use in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory airway disease characterized by non-reversible airflow limitation and...
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Chronic Obstructive Pulmonary Disease (COPD)
Effective COPD diagnosis and disease stratification is largely hindered due to presence of symptomatic similarity with other lung diseases and...
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Functional Activity of Blood Neutrophils in Patients with Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease
We performed a comparative study of the parameters of chemiluminescence of blood neutrophils in patients with different severity of chronic...
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Peroxiredoxin 6 Protects Pulmonary Epithelial Cells From Cigarette-related Ferroptosis in Chronic Obstructive Pulmonary Disease
Peroxiredoxin 6 (PRDX6) has a protective effect on pulmonary epithelial cells against cigarette smoke (CS)-induced ferroptosis. This study...
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Assessing Lung Inflammation and Pathology in Preclinical Models of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is an incurable disease that is a major cause of mortality and morbidity worldwide. Cigarette smoking is...
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Evaluation of asthma–chronic obstructive pulmonary disease overlap using a mouse model of pulmonary disease
BackgroundFeatures of asthma and chronic obstructive pulmonary disease (COPD) can coexist in the same patient, in a condition termed asthma– chronic...
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Revolutionizing Chronic Obstructive Pulmonary Disease Care with the Open AI Application: ChatGPT
Chronic Obstructive Pulmonary Disease (COPD) is one of the major and leading threats to human being. To cope with this health challenge, several...
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Associations between chronic obstructive pulmonary disease and ten common cancers: novel insights from Mendelian randomization analyses
BackgroundChronic obstructive pulmonary disease (COPD) is a significant global health issue, suspected to elevate the risk for various cancers. This...
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Endoplasmic reticulum stress: a vital process and potential therapeutic target in chronic obstructive pulmonary disease
BackgroundChronic obstructive pulmonary disease (COPD), a chronic and progressive disease characterized by persistent respiratory symptoms and...
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Application of an Integrative Drug Safety Model for Detection of Adverse Drug Events Associated With Inhibition of Glutathione Peroxidase 1 in Chronic Obstructive Pulmonary Disease
BackgroundChronic Obstructive Pulmonary Disease is characterised by declining lung function and a greater oxidative stress burden due to reduced...
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Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the leading causes of mortality worldwide. Cigarette smoking is among the...
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Melatonin and mesenchymal stem cells co-administration alleviates chronic obstructive pulmonary disease via modulation of angiogenesis at the vascular-alveolar unit
Chronic obstructive pulmonary disease (COPD) is considered a severe disease mitigating lung physiological functions with high mortality outcomes,...
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Assessment of NLRP3 inflammasome activation in patients with chronic obstructive pulmonary disease before and after lung transplantation
The interplay between purinergic receptors as well as pattern recognition receptors like Toll-like receptors (TLRs) and NOD-, LRR-, and pyrin...
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A computational musculoskeletal arm model for assessing muscle dysfunction in chronic obstructive pulmonary disease
Computational models have been used extensively to assess diseases and disabilities effects on musculoskeletal system dysfunction. In the current...
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Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Chronic obstructive pulmonary disease (COPD) affects over 250 million individuals globally and stands as the third leading cause of mortality....
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Comparative Study of the Levels of IL-1β, IL-4, IL-8, TNFα, and IFNγ in Stable Course and Exacerbation of Chronic Obstructive Pulmonary Disease of Varying Severity
In patients with chronic obstructive pulmonary disease, the levels of cytokines IL-1β, IL-4, IL-8, TNFα, and IFNγ depended on the degree of bronchial...
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Down-regulated HHLA2 enhances neoadjuvant immunotherapy efficacy in patients with non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease (COPD)
BackgroundEmerging data suggested a favorable outcome in advanced non-small cell lung cancer (NSCLC) with chronic obstructive pulmonary disease...
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A journey to unravel the pathophysiology of stable and exacerbated Chronic Obstructive Pulmonary Disease through erythrocyte proteomics: a combined mass spectrometry/bioinformatics approach
Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disorder with high mortality. The present study explores the novel and highly...
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Endothelial progenitor cells systemic administration alleviates multi-organ senescence by down-regulating USP7/p300 pathway in chronic obstructive pulmonary disease
BackgroundChronic obstructive pulmonary disease (COPD) has impacted approximately 390 million people worldwide and the morbidity is increasing every...
