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MUC1 promotes cervical squamous cell carcinoma through ERK phosphorylation-mediated regulation of ITGA2/ITGA3
In contrast to the decreasing trends in developed countries, the incidence and mortality rates of cervical squamous cell carcinoma in China have...
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Clinical features and imaging examination assessment of cervical lymph nodes for thyroid carcinoma
BackgroundsThe purpose of this study is to investigate the relationship between clinical characteristics and cervical lymph node metastasis (LNM) in...
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HER2 mutations in advanced cervical neuroendocrine carcinoma: implications for trastuzumab deruxtecan therapy
Recent clinical evidence shows that the antibody-drug conjugate (ADC) trastuzumab deruxtecan (T-DXd) can successfully treat patients with advanced...
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Transdifferentiation of cervical squamous cell carcinoma with ERBB2 amplification to adenocarcinoma: whole genome sequence analysis and successful control by anti-HER2 therapy
Cancer cells sometimes transdifferentiate into different histological type(s) and tumors with multiple histological types can share a common ancestor...
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HPV genotypes in high-grade cervical lesions and invasive cervical carcinoma detected in Gabonese women
BackgroundCervical cancer is the third most common cancer among women worldwide, but particularly affects women living in sub-Saharan Africa....
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Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance
Cervical squamous cell carcinoma (CSCC) exhibits a limited response to immune-checkpoint blockade. Here we conducted a multiomic analysis...
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The value of HPV genotypes combined with clinical indicators in the classification of cervical squamous cell carcinoma and adenocarcinoma
BackgroundTo investigate the differences in HPV genotypes and clinical indicators between cervical squamous cell carcinoma and adenocarcinoma and to...
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Impact of CD40 gene polymorphisms on the risk of cervical squamous cell carcinoma: a case-control study
BackgroundCervical cancer is the fourth most common cancer among women worldwide. Genome-wide association studies have revealed multiple susceptible...
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CXCL10 serves as a potential serum biomarker complementing SCC-Ag for diagnosing cervical squamous cell carcinoma
BackgroundCervical squamous cell carcinoma (CESC) is the most common histological type of cervical cancer which is the major cause of death in women...
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USP39 interacts with SIRT7 to promote cervical squamous cell carcinoma by modulating autophagy and oxidative stress via FOXM1
BackgroundSirtuin 7 (SIRT7) is an oncogene that promotes tumor progression in various malignancies, however, its role and regulatory mechanism in...
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Improve individual treatment by comparing treatment benefits: cancer artificial intelligence survival analysis system for cervical carcinoma
PurposeThe current study aimed to construct a novel cancer artificial intelligence survival analysis system for predicting the individual mortality...
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Efficacy of treatment patterns based on concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma
PurposeTo assess survival of treatment patterns based on concurrent chemoradiotherapy (CCRT) in patients with stage IIB cervical squamous cell...
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Synbiotics in Cervical Cancer
The gut microbiota is usually regarded as one of the most crucial aspects in maintaining homeostasis. Probiotic microbes have been proven to come up...
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Neoadjuvant chemotherapy followed by surgery versus concurrent chemoradiotherapy in patients with stage IIB cervical squamous cell carcinoma: a retrospective cohort study
PurposeThis study aims to compare treatment outcomes between neoadjuvant chemotherapy (NACT) followed by surgery and concurrent chemoradiotherapy...
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Association between human herpesvirus infection and cervical carcinoma: a systematic review and meta-analysis
BackgroundCervical cancer (CC) is one of the most common gynecologic tumors among women around the world. Although the etiological role of human...
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Elective nodal irradiation versus involved-field irradiation for stage II–IV cervical esophageal squamous cell carcinoma patients undergoing definitive concurrent chemoradiotherapy: a retrospective propensity study with 8-year survival outcomes
BackgroundDefinitive concurrent chemoradiotherapy (dCCRT) is suggested as the standard treatment for cervical esophageal squamous cell carcinoma...
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Microendoscopy in vivo for the pathological diagnosis of cervical precancerous lesions and early cervical cancer
BackgroundCervical cancer is an important public health problem. Conventional colposcopy is inefficient in the diagnosis of cervical lesions and...
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Immunotherapy for Cervical Cancer
Cervical cancer is a highly prevalent gynecological malignancy worldwide, and it is associated with high-risk human papillomavirus (HPV) infection....
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Tumor histology is an independent prognostic factor in locally advanced cervical carcinoma: A retrospective study
BackgroundEven with different histologic origins, squamous cell carcinoma (SCC) and adenocarcinoma (AC) are considered a single entity, and the...
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Promoter hypermethylation analysis of host genes in cervical intraepithelial neoplasia and cervical cancers on histological cervical specimens
BackgroundDNA methylation is an essential factor in the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer. The aim was to...
