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Tumor Heterogeneity in Breast Cancer Progression
Cancer is an aberrant growth of cells with dynamic molecular changes as the disease progresses. As a result of these dynamic changes and an increase...
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Crucial Metabolic Networks: Cancer Progression
The study of metabolic networks in cancer cells is essential for understanding the fundamental properties of living systems and how metabolic...
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Cancer Stem Cells in Cancer Initiation and Progression
Cancer stem cells (CSCs) are a subclass of cancer cells that can differentiate into various cell types and self-renew, similar to normal stem cells....
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Tumor Heterogeneity in Breast Cancer Progression
Cancer is an aberrant growth of cells with dynamic molecular changes as the disease progresses. As a result of these dynamic changes and an increase...
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Hypoxic Tumor Microenvironment: Driver for Cancer Progression
Hypoxia or low oxygen concentration is one of the major physiological parameters within tumor microenvironment (TME). It has a profound effect in...
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Crucial Metabolic Networks: Cancer Progression
The study of metabolic networks in cancer cells is essential for understanding the fundamental properties of living systems and how metabolic...
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A Comprehensive Overview of Various Cancer Types and Their Progression
Cancer is one of the leading causes of death and is a major public health issue that drives the attention of many scientific communities across the...
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Cancer-derived exosomal Alu RNA promotes colorectal cancer progression
Inflammation plays a crucial role in cancer progression, but the relevance of the inflammasome remains unclear. Alu RNA was the first endogenous...
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The Cancer Stem Cell and Tumour Progression
Tumour stem cells result from genetic or chromosomal changes in normal tissue stem cells, i.e. cells with self-renewal capability. Subsequent tumour...
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Role of mitochondrial alterations in human cancer progression and cancer immunity
Dysregulating cellular metabolism is one of the emerging cancer hallmarks. Mitochondria are essential organelles responsible for numerous physiologic...
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Eph receptors and ephrins in cancer progression
Evidence implicating Eph receptor tyrosine kinases and their ephrin ligands (that together make up the ‘Eph system’) in cancer development and...
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A Comprehensive Overview of Various Cancer Types and Their Progression
Cancer is one of the leading causes of death and is a major public health issue that drives the attention of many scientific communities across the...
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Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter
BackgroundOvarian cancer (OC) is distinguished by its aggressive nature and the limited efficacy of current treatment strategies. Recent studies have...
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miRNAs in pancreatic cancer progression and metastasis
Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells. Dysregulation of miRNA expression and function has been linked...
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Dexmedetomidine promotes colorectal cancer progression via Piwil2 signaling
Purposeα2-adrenoceptor agonist dexmedetomidine (DEX) has been reported to promote tumorigenesis. Stem-cell protein Piwil2 is associated with cancer...
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Transfer RNAs as dynamic and critical regulators of cancer progression
Transfer RNAs (tRNAs) have been historically viewed as non-dynamic adaptors that decode the genetic code into proteins. Recent work has uncovered...
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The effects of intracellular and exosomal ncRNAs on cancer progression
Altered gene expression as well as mislocalization of a gene’s encoded product (proteins or noncoding RNAs (ncRNAs)) can lead to disease and cancer...
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CDKs in Cell-Cycle Progression and Therapeutic Strategies in Human Breast Cancer
One of the deadly diseases in terms of incidence and mortality among females is breast cancer (BC), it is escalating at an alarming rate having...
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Role of epithelial splicing regulatory protein 1 in cancer progression
As aberrant alternative splicing by either dysregulation or mutations of splicing factors contributes to cancer initiation and progression, splicing...
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Histone Demethylase KDM3 (JMJD1) in Transcriptional Regulation and Cancer Progression
Methylation of histone H3 lysine 9 (H3K9) is a repressive histone mark and associated with inhibition of gene expression. KDM3 is a subfamily of the...