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Thermogenic Fat Methods and Protocols
This volume presents a broad collection of state-of-the-art methods to study the biology of thermogenic fat using in vitrocell culture and animal...
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Changes in brown adipose tissue induced by resveratrol and its analogue pterostilbene in rats fed with a high-fat high-fructose diet
Natural bioactive compounds have attracted a great deal of attention since some of them can act as thermogenesis activators. In recent years, special...
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AAV-Mediated Gene Delivery to Mouse Brown Adipose Tissue
Recombinant adeno-associated virus (AAV) vectors are attractive vehicles for gene therapy. Yet targeting adipose tissue is still a challenging task....
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Isolation and Characterization of Brown Adipose Tissue T Cells
Brown adipose tissue (BAT) is a specialized fat depot that can dissipate energy through uncoupled respiration and thermogenesis. Various immune cells...
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Long noncoding RNA XIST regulates brown preadipocytes differentiation and combats high-fat diet induced obesity by targeting C/EBPα
BackgroundActivation of brown adipose tissue (BAT) increases energy expenditure, which makes it an attractive therapeutic strategy for obesity....
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Brown adipose tissue fat-fraction is associated with skeletal muscle adiposity
PurposeWhile brown adipose tissue (BAT) activity is known to be associated with both muscle and adipose tissue volumes, the association between BAT...
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Assessment of Brown and Beige Adipose Tissue Activation in Mice Using PET/CT Imaging
In response to cold induction, brown adipose tissues (BAT) and emerged brown-like adipocytes (beige adipocytes) in subcutaneous white adipose tissues...
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Dapagliflozin promotes white adipose tissue browning though regulating angiogenesis in high fat induced obese mice
Browning of white adipose tissue (WAT) is become an appealing target for therapeutics in the treatment of obesity and related metabolic diseases....
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Measuring Mitochondrial Uncoupling in Mouse Primary Brown Adipocytes Differentiated Ex Vivo
Measuring the mitochondrial respiratory capacity of brown adipocytes ex vivo is an essential approach to understand the cell-autonomous regulators of...
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Differential remodeling of subcutaneous white and interscapular brown adipose tissue by long-term exercise training in aged obese female mice
Obesity exacerbates aging-induced adipose tissue dysfunction. This study aimed to investigate the effects of long-term exercise on inguinal white...
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Use of CIDEA Reporter Mouse Model for Screening Thermogenic Fat-Activating Drugs
Excessive fat accumulation is a risk factor for metabolic diseases. Activating non-shivering thermogenesis in adipose tissue increases energy...
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Isolation and Mass Spectrometry-Based Profiling of Major Lipids in Brown Adipose Tissue
Brown adipose tissue (BAT) is an important regulator of metabolic homeostasis through its role in adaptive thermogenesis and control of whole-body...
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Brown adipose tissue and alzheimer’s disease
Alzheimer’s disease (AD), the most common type of senile dementia, is a chronic neurodegenerative disease characterized by cognitive dysfunction and...
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What is the role of brown adipose tissue in metabolic health: lessons learned and future perspectives in the long COVID?
Metabolic physiology plays a key role in maintaining our health and resilience. Metabolic disorders can lead to serious illnesses, including obesity....
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Multigrain for Low-calorie, Low-fat, and High-fiber Food
Purpose of ReviewThis review examines the trends in multigrain food products over the last five years and evaluates the accuracy and implications of...
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Long-term effects of a fat-directed FGF21 gene therapy in aged female mice
Fibroblast growth factor 21 (FGF21) has been developed as a potential therapeutic agent for metabolic syndromes. Moreover, FGF21 is considered a...
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Muscle and fat composition in patients with newly diagnosed multiple myeloma
Measures of muscle and adipose tissue mass have been associated with outcomes in several malignancies, but studies in multiple myeloma (MM) are...
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Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy
Epicardial adipose tissue surrounds and infiltrates the heart. Epicardial fat displays unique anatomic, genetic, and biomolecular properties. People...
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Involvement of mechano-sensitive Piezo1 channel in the differentiation of brown adipocytes
Brown adipocytes expend energy via heat production and are a potential target for the prevention of obesity and related metabolic disorders. Piezo1...
