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Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea
BackgroundTherapy-related myeloid neoplasm (T-MN) rarely occurs among cancer survivors, and was characterized by poor prognosis. T-MN has germline...
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Breast Cancer
Breast cancer is currently the most diagnosed cancer in the female population, with a prevalence of 1 in 8 women.
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Mechanisms of Drug Resistance in Breast Cancer
The incidence of breast cancer has increased over the past decades making it the most common cancer in females worldwide. Multidrug resistance (MDR)...
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Effectiveness of epidural morphine for the treatment of cancer pain in patients with gastrointestinal neoplasm—a systematic review
One-third of cancer pain patients do not experience adequate pain relief using analgesic ladder by the World Health Organization. Interventional...
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Breast Tumor Microenvironment and CDKs
Breast malignancy is one of the most frequently diagnosed carcinoma in women globally, and it is also the common reason for tumor-associated fatality...
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Animal Models in Cancer Research: Breast Cancer
This chapter covers the main animal models employed in basic research to study breast cancer, including murine (chemically induced, transplanted,...
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Epigenetic regulation of breast cancer metastasis
Breast cancer is the most frequently diagnosed malignancy and the second leading cause of cancer-related mortality among women worldwide. Recurrent...
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Dose response relationship between breast cancer and somatotypes during childhood: a systematic review and meta-analysis
ObjectivesThis study aims to evaluate the relationship between breast cancer and somatotypes during early life by meta-analysis and give the...
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Risks of second non-breast primaries following breast cancer in women: a systematic review and meta-analysis
BackgroundSecond primary cancer incidence is rising among breast cancer survivors. We examined the risks of non-breast second primaries, in...
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Upregulation of CENPM promotes breast carcinogenesis by altering immune infiltration
BackgroundThe involvement of centromere protein M (CENPM) in various types of cancer has been established, however, its impact on breast cancer and...
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Histopathological Characteristics: Breast Cancer Subtypes Depending on Receptor Status, Clinical and Pathological Staging of Breast Cancer
Breast cancer (BC) is a clinically heterogeneous disease affecting around 14% female population worldwide with unique histopathological and...
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Radiotherapy versus low-dose tamoxifen following breast-conserving surgery for low-risk and estrogen receptor-positive breast ductal carcinoma in situ: an international open-label randomized non-inferiority trial (TBCC-ARO DCIS Trial)
BackgroundRadiotherapy (RT) following breast-conserving surgery (BCS) is mainly used to decrease the rate of ipsilateral breast tumor recurrence...
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HER2 Testing in Breast and Gastric Cancer with CDH1 Germline Mutations
The role of human epidermal growth factor receptor-2 (HER2) is involved in epithelial cells growth and differentiation and has been widely studied in...
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Impact of NDUFAF6 on breast cancer prognosis: linking mitochondrial regulation to immune response and PD-L1 expression
BackgroundBreast cancer is a major global health concern, and there is a continuous search for novel biomarkers to predict its prognosis. The...
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Insulin receptor alternative splicing in breast and prostate cancer
Cancer etiology represents an intricate, multifactorial orchestration where metabolically associated insulin-like growth factors (IGFs) and insulin...
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Targeting cholesterol impairs cell invasion of all breast cancer types
BackgroundBreast cancer clinical outcome relies on its intrinsic molecular subtype and mortality is almost exclusively due to metastasis, whose...
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Dietary pattern and other factors of breast cancer among women: a case control study in Northwest Ethiopia
IntroductionBreast cancer is presently the most commonly diagnosed cancer in women, and it stands as the leading cause of cancer-related deaths...
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Association between NDRG1 protein expression and aggressive features of breast cancer: a systematic review and meta-analysis
BackgroundN-myc downstream-regulated gene-1 (NDRG1) is well-described as a potent metastasis suppressor, but its role in human breast cancer remains...
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SPDYC serves as a prognostic biomarker related to lipid metabolism and the immune microenvironment in breast cancer
Breast cancer remains the most common malignant carcinoma among women globally and is resistant to several therapeutic agents. There is a need for...
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Metabolic abnormalities and survival among patients with non-metastatic breast cancer
BackgroundResearch on the impact of metabolic abnormalities on breast cancer prognosis is limited by small samples and assessment of laboratory...
