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Apoptosis and Cancer Methods and Protocols
This volume discusses methods used in the fields of molecular and cellular biology for detecting and studying cell death, especially in cancer and...
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Apoptosis in Cancer
Background: The life of multicellular creatures is safeguarded by the equilibrium between the constant proliferation of their cells and the...
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Apoptosis and Phagocytosis as Antiviral Mechanisms
Viruses are infectious entities that make use of the replication machinery of their hosts to produce more progenies, causing disease and sometimes...
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Mechanisms of Neuronal Apoptosis and Excitotoxicity
Neurons are postmitotic cells that may remain functional for years and cannot be replaced easily, so irreversible neuronal damage could result in...
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Cancer and Apoptosis
Cancer is an uncontrolled growth of normal cells due to unchecked regulatory mechanisms working inside the rapidly dividing cells. In this complex...
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Oxidative Stress, Redox Signaling, and Apoptosis in Prostate Cancer Development and Progression
Prostate cancer (PC) is one of the most common tumors in the male population. One of the possible causes of cancer is reactive oxygen species (ROS)....
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Hypoxia-Induced Apoptosis in Cancer Development
According to World Health Organization reports, cancer is the leading cause of mortality, accounting for approximately ten million deaths or 1 in 6...
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ROS/Redox Signaling and Apoptosis/Necroptosis/Autophagy in Cancer
This chapter entitled “ROS/Redox Signaling and Apoptosis/Necroptosis/Autophagy in Cancer” initially provides a brief account of various programmed...
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Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development
Development is an evolutionary process that is tightly regulated in mammalian species. Several different cascades are involved in various stages of...
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Automated Immunofluorescence Staining for Analysis of DNA Damage and Apoptosis in Brain Sections
Neural progenitors show a strong tendency to undergo apoptosis in response to DNA damage, and both impaired DNA repair and increased neural...
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Apoptosis
Cell death by apoptosis serves as an important regulatory mechanism to eliminate cells following differentiation in the bone marrow and also during...
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Effect of Lysine Acridone Acetate on the Level of Apoptosis and Expression of Apoptosis-Associated Proteins during Antioncogenic Therapy in Colorectal Cancer in Mice
We studied the mechanism of action of cytostatics with the addition of lysine acridone acetate to evaluate the possibility of its use for improving...
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Beyond Death: Unmasking the Intricacies of Apoptosis Escape
Apoptosis, or programmed cell death, maintains tissue homeostasis by eliminating damaged or unnecessary cells. However, cells can evade this process,...
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N6-Methyladenosine Methylation of mRNA in Cell Apoptosis
Apoptosis, a highly controlled homeostatic mechanism that eliminates single cells without destroying tissue function, occurs during growing...
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Apoptosis and eryptosis: similarities and differences
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a counterpart of apoptosis for enucleated cells. However,...
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AIFM1 variants associated with auditory neuropathy spectrum disorder cause apoptosis due to impaired apoptosis-inducing factor dimerization
Auditory neuropathy spectrum disorder (ANSD) represents a variety of sensorineural deafness conditions characterized by abnormal inner hair cells...
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ROS in Apoptosis of Cancer Cells
Carcinogenesis is a complex and multistep process ending with metastasis. Mainly, gene and metabolic pathways include endogenous and signaling...
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ROS-Mediated Apoptosis in Cancer
Redox homeostasis is defined as a balance between reactive oxygen species (ROS) production and ROS elimination. Intracellular ROS are produced during...
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Curcumin attenuates brain aging by reducing apoptosis and oxidative stress
Brain aging is a physiological event, and oxidative stress and apoptosis are involved in the natural aging process of the brain. Curcumin is a...
