Search
Search Results
-
ANA-specific antibodies, ANA patterns, anti-ds-DNA results, and clinical diagnosis: a laboratory and clinical audit
The diagnosis of systemic autoimmune diseases (SAID) is challenging, due to overlap** features with other non-immune disorders. Anti-nuclear...
-
Correlation analysis between auto-immunological and mutational profiles in myelodysplastic syndromes
Objective and designSystemic-Inflammatory-Autoimmune-Diseases (SIAD) is increasingly considered in Myelodysplastic-Syndromes (MDS). In this line, we...
-
Current laboratory and clinical practices in reporting and interpreting anti-nuclear antibody indirect immunofluorescence (ANA IIF) patterns: results of an international survey
BackgroundThe International Consensus on Antinuclear Antibody (ANA) Patterns (ICAP) has recently proposed nomenclature in order to harmonize ANA...
-
Prevalence, clinical significance, and persistence of autoantibodies in COVID-19
BackgroundInterest in complications and sequelae following Coronavirus disease 2019 (COVID-19) is increasing. Several articles have reported...
-
Antinociceptive and anti-inflammatory activity of extracts and α-pyrones isolated from Cantinoa stricta
This study evaluated the composition and the antinociceptive and anti-inflammatory activity of the crude extracts and two isolated compounds,...
-
Laboratory and clinical practices in antinuclear antibody detection and related antigens: recommendations from a Spanish multicentre survey
Antinuclear antibodies (ANA) are the most widely used immunological test for the diagnosis of autoimmune diseases. Despite the recommendations of...
-
Letter F
Farr method (Farr assay, Farr immunoprecipitation assay) quantifies the antidouble-stranded DNA (anti-dsDNA) antibodies—that is, antinuclear... -
Related factors of renal injury in primary Sjögren's syndrome
BackgroundPrimary Sjögren’s syndrome (pSS) is a common chronic systemic autoimmune disorder which primarily affects the exocrine glands. Patients may...
-
How to report the antinuclear antibodies (anti-cell antibodies) test on HEp-2 cells: guidelines from the ICAP initiative
Results of the anti-nuclear antibodies-indirect immunofluorescence assay (anti-cell antibodies test) on HEp-2 cell substrates should be communicated...
-
SHP2: its association and roles in systemic lupus erythematosus
ObjectiveSystemic lupus erythematosus (SLE) is an autoimmune inflammatory disease. Src homology 2 domain containing protein tyrosine phosphatase...
-
Risk of Early Infection in Idiopathic Inflammatory Myopathies: Cluster Analysis Based on Clinical Features and Biomarkers
Patients with idiopathic inflammatory myopathies (IIMs), referred to as myositis, are prone to infectious complications, which hinder the treatment...
-
RhANP attenuates endotoxin-derived cognitive dysfunction through subdiaphragmatic vagus nerve-mediated gut microbiota–brain axis
BackgroundAtrial natriuretic peptide (ANP) secreted from atrial myocytes is shown to possess anti-inflammatory, anti-oxidant and immunomodulatory...
-
IL-38, a potential therapeutic agent for lupus, inhibits lupus progression
BackgroundPrevious studies reported that IL-38 was abnormally expressed in patients with systemic lupus erythematosus (SLE). However, the involvement...
-
Chemokine CXCL1 as a potential marker of disease activity in systemic lupus erythematosus
ObjectivesThe chemokine CXCL1, known as growth-related oncogene α (GRO-α), is a potent chemoattractant and regulator of neutrophils. The purpose of...
-
Evaluation of a novel particle-based multi-analyte technology for the detection of anti-fibrillarin antibodies
Systemic sclerosis (SSc) is a heterogeneous autoimmune disease associated with several anti-nuclear antibodies (ANA), including those in the...
-
Post-COVID-19 arthritis: is it hyperinflammation or autoimmunity?
BackgroundVarious musculoskeletal and autoimmune manifestations have been described in patients with coronavirus disease 2019 (COVID-19).
... -
Inhibition of P2X4R attenuates white matter injury in mice after intracerebral hemorrhage by regulating microglial phenotypes
BackgroundWhite matter injury (WMI) is a major neuropathological event associated with intracerebral hemorrhage (ICH). P2X purinoreceptor 4 (P2X4R)...
-
ANCA-negative microscopic polyangiitis with diffuse alveolar hemorrhage masquerading as congestive heart failure
BackgroundMicroscopic polyangiitis (MPA) is a subtype of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV), involving small and medium...
-
Autoimmune liver disease-associated serologic profiling in Chinese patients with acute hepatitis E virus infection
The association between hepatitis E virus (HEV) and autoimmune liver diseases has been well-researched; however, the focus has been on autoimmune...
-
Purification of Autoantibodies Bound to an Autoantigen Immobilized on a Membrane Strip
This chapter describes a technique for purifying autoantibodies off a membrane strip using small human sera volumes. This method used a membrane...