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SARS-CoV-2 immunity in animal models
The COVID-19 pandemic, which was caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a worldwide health crisis due to...
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Experimental Animal Models
Human scabies is a cutaneous parasitosis caused by the microscopic mite Sarcoptes scabiei var. hominis. The disease is a major public health concern,...
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Animal Models of Vasculitis
The diagnosis of vasculitis in rheumatoid arthritis (RV) is associated with considerable mortality; therefore, understanding the basic mechanisms...
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Animal Models for Mania
Manic episodes are assigned to the classification of affective disorders and oftentimes occur as a moodMoods episode in the course of bipolar...
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Animal Models of Tuberculosis
Tuberculosis (TB) is an important zoonotic disease caused by infection with Mycobacterium tuberculosis (Mtb) complex and has a significant impact on...
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Therapeutic advances in atrial fibrillation based on animal models
Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age....
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Animal Models of ASD
The similarities between humans and animals are useful for studies of the central nervous system, and animal models have often been used in...
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Animal Models for Cancer Immunology
Purpose of ReviewThis review discusses the characteristics of different in vivo experimental immunologic models for the development of...
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Challenges and opportunities in animal models of psoriatic arthritis
ObjectiveTo review the preparation, characteristics and research progress of different PsA animal models.
MethodsComputerized searches were...
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Molecular Pathways and Animal Models of Arrhythmias
Arrhythmias account for over 300,000 annual deaths in the United States, and approximately half of all deaths are associated with heart disease....
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Animal Models in Cancer Research
Cancer remains one of the most debilitating diseases in the world as it ranks the second leading cause of mortality. Researchers are relying on...
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Disease Animal Models for Cancer Research
Despite nonanimal methods (NAMs) are more and more exploited and new NAMs are developed and validated, animal models are still used in cancer...
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Meningioma animal models: a systematic review and meta-analysis
BackgroundAnimal models are widely used to study pathological processes and drug (side) effects in a controlled environment. There is a wide...
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Human Brain Penetration Prediction Using Scaling Approach from Animal Machine Learning Models
Machine learning (ML) approaches have been applied to predicting drug pharmacokinetic properties. Previously, we predicted rat unbound...
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Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges
In order to dissect amyotrophic lateral sclerosis (ALS), a multigenic, multifactorial, and progressive neurodegenerative disease with heterogeneous...
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Alternative Animal Models in Cancer Research
Cancer, a broad word encompassing a range of diseases characterized by the excessive division of abnormal cells, has emerged as a major public health...
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Animal Models for Hepatitis E Virus
Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light...
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Animal Welfare Aspects in Planning and Conducting Experiments on Rodent Models of Subarachnoid Hemorrhage
Subarachnoid hemorrhage is an acute life-threatening cerebrovascular disease with high socio-economic impact. The most frequent cause, the rupture of...
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Animal Models of Gynecological Cancers
Gynecological cancers develop in the reproductive organs of a woman. The common gynecological cancers are cervical, ovarian, uterine, vaginal, and...