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Recent advances in albumin nanoparticle-based cancer therapies
BackgroundNanotechnology is increasingly utilized in treating complex and challenging diseases, notably cancer. Among the emerging strategies,...
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Albumin: a comprehensive review and practical guideline for clinical use
PurposeNowadays, it is largely accepted that albumin should not be used in hypoalbuminemia or for nutritional purpose. The most discussed indication...
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Anxious and Melancholic Depression Are Associated with Oppositely Directed Changes in Serum Albumin Conformation
Abstract —The study was aimed at investigating the peculiarities of the conformational changes in serum albumin in patients with anxious and...
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Defining albumin as a glycoprotein with multiple N-linked glycosylation sites
BackgroundGlycosylation is an enzyme-catalyzed post-translational modification that is distinct from glycation and is present on a majority of plasma...
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Mouse serum albumin induces neuronal apoptosis and tauopathies
The elderly frequently present impaired blood–brain barrier which is closely associated with various neurodegenerative diseases. However, how the...
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Association between serum albumin levels and height loss in Japanese workers: a retrospective study
BackgroundHeight loss starting in middle age was previously shown to be associated with high cardiovascular mortality in later life. However, the...
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Association between underweight, serum albumin levels, and height loss in the Japanese male population: a retrospective study
BackgroundPrevious study has shown that height loss (defined as the highest quartile of height loss per year) was inversely associated with serum...
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Ischemia-Modified Albumin and Antioxidant Protection in Newborns with Asphyxia of Varying Severity
The content of ischemia-modified albumin (IMA), serum albumin, and antioxidant capacity of blood serum was studied in healthy newborns and in...
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Assessment of fibrinogen albumin ratio in patients with pregnancy-related cerebral venous thrombosis
Introduction and objectiveCerebral venous thrombosis (CVT) is a cerebrovascular disease observed more commonly in women of childbearing age. There is...
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The Role of Glycated Albumin as a Biomarker of Glycemic Control in Diabetes and Chronic Kidney Disease
Albumin is the most abundant protein found in plasma and constitutes approximately 60% of all proteins in the blood. This high molecular weight...
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Ameliorative effects of Copper(II) albumin complex against zinc oxide nanoparticles induced oxidative DNA damage in Sprague Dawley rats
ObjectiveThe present study was carried out to investigate the possible protective role of copper (II) albumin against zinc oxide nanoparticles...
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Temporal tracking of cysteine 34 oxidation of plasma albumin as a biomarker of muscle damage following a bout of eccentric exercise
PurposeExercise-induced muscle damage (EIMD) results in the generation of reactive oxygen species (ROS), but little is known about the temporal...
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The Redox State of Serum Albumin as a Potential Protein Nutrition Biomarker
Albumin comprises the largest part of total serum proteins in humans and is exclusively synthesized in the liver, before being distributed into the...
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A Quality by Design Paradigm for Albumin-Based Nanoparticles: Formulation Optimization and Enhancement of the Antitumor Activity
PurposeAlbumin nanoparticles are promising carriers for therapeutic agents, owing to their biocompatibility, safety, and versatility in fabrication....
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Nitric oxide-releasing albumin nanoclusters facilitate healing of methicillin-resistant Staphylococcus aureus-infected cutaneous wounds
PurposeAlthough nitric oxide (NO)-releasing nanoparticles have garnered significant attention owing to their potent antibacterial effects against...
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The Redox State of Serum Albumin as a Potential Protein Nutrition Biomarker
Albumin comprises the largest part of total serum proteins in humans and is exclusively synthesized in the liver, before being distributed into the...
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Inhibitory Potential of Carnosine and Aminoguanidine Towards Glycation and Fibrillation of Albumin: In-vitro and Simulation Studies
Carnosine is beta-alanyl histidine, a dipeptide, endogenously produced in our body by the carnosine synthase enzyme. It is an antioxidant, thus...
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Quality by design empowered preparation of itraconazole albumin nanoparticles for prostate cancer
The current advent explores the potential of itraconazole (ITR) in prostate cancer (PCa), by its incorporation into albumin nanoparticles (NP). ITR...
