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The role of adenocarcinoma subtypes and immunohistochemistry in predicting lymph node metastasis in early invasive lung adenocarcinoma
BackgroundIdentifying lymph node metastasis areas during surgery for early invasive lung adenocarcinoma remains challenging. The aim of this study...
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Rab3B enhances the stabilization of DDX6 to promote lung adenocarcinoma aggressiveness
BackgroundLiver kinase B1 ( LKB1 ) is frequently mutated in lung adenocarcinoma, and its loss contributes to tumor progression.
Methods ...
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Amino acids and risk of colon adenocarcinoma: a Mendelian randomization study
BackgroundThe existence of amino acid metabolic reprogramming in tumor cells is well established. However, the potential correlation between blood...
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MiR-181c-5p Regulates Lung Adenocarcinoma Progression via Targeting PRKN
Accumulating evidence indicates that microRNAs (miRNAs) have a vital effect on lung adenocarcinoma. However, the contributions and possible...
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Analysis of cancer-associated fibroblasts related genes identifies COL11A1 associated with lung adenocarcinoma prognosis
BackgroundThe treatment of lung adenocarcinoma is difficult due to the limited therapeutic options. Cancer-associated fibroblasts play an important...
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Construction of 11 metabolic-related lncRNAs to predict the prognosis in lung adenocarcinoma
ObjectiveTo explore the metabolism-related lncRNAs in the tumorigenesis of lung adenocarcinoma.
MethodsThe transcriptome data and clinical...
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A Method for Culturing 3D Tumoroids of Lung Adenocarcinoma Cells at the Air–Liquid Interface
Three-dimensional (3D) tumor spheroids and tumoroids are among the most exploited cell culture methods in the lung cancer field, finding applications...
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The value of CT shape quantification in predicting pathological classification of lung adenocarcinoma
ObjectiveTo evaluate whether quantification of lung GGN shape is useful in predicting pathological categorization of lung adenocarcinoma and guiding...
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A novel transformer-based aggregation model for predicting gene mutations in lung adenocarcinoma
AbstractIn recent years, predicting gene mutations on whole slide imaging (WSI) has gained prominence. The primary challenge is extracting global...
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MicroRNA 29a therapy for CEACAM6-expressing lung adenocarcinoma
BackgroundNon-coding microRNAs (miRNAs) play critical roles in tumor progression and hold great promise as therapeutic agents for multiple cancers....
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Total neoadjuvant therapy in oesophageal and gastro-oesophageal junctional adenocarcinoma
Adenocarcinoma of the oesophagus and gastro-oesophageal junction represent a large burden of cancer death in the Western World with an increasing...
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Generation and Characterization of an Isogenic Cell Line Model of Radioresistant Esophageal Adenocarcinoma
Radiation therapy is a cornerstone of cancer treatment worldwide. Unfortunately, in many cases, it does not control tumor growth, and many tumors...
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CXCR3 predicts the prognosis of endometrial adenocarcinoma
ObjectivesCurrently, endometrial adenocarcinoma lacks an effective prognostic indicator. This study was to develop and validate a gene biomarker and...
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EGFL6 promotes bone metastasis of lung adenocarcinoma by increasing cancer cell malignancy and bone resorption
AbstractLung adenocarcinoma is the most common and aggressive type of lung cancer with the highest incidence of bone metastasis. Epidermal growth...
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Effects of TRAF3 on the proliferation and migration of lung adenocarcinoma depend partly on pyroptosis
BackgroundTumor necrosis factor receptor-associated factor 3 (TRAF3) has specific regulatory effects on a wide range of diseases, including tumors....
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25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis
Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes...
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Liquid-based cytology specimens for next-generation sequencing in lung adenocarcinoma: challenges and evaluation of targeted therapy
BackgroundTo explore challenges of liquid-based cytology (LBC) specimens for next-generation sequencing (NGS) in lung adenocarcinoma and evaluate the...
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Topology and adenocarcinoma cell localization dataset on the labyrinthin diapeutic biomarker
ObjectiveThe discovery and characterization of tumor associated antigens is increasingly important to advance the field of immuno-oncology. In this...
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Genome-wide somatic mutation analysis of sinonasal adenocarcinoma with and without wood dust exposure
BackgroundSinonasal adenocarcinoma is a rare cancer, encompassing two different entities, the intestinal-type sinonasal adenocarcinoma (ITAC) and the...
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Zolbetuximab plus CAPOX in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma: the randomized, phase 3 GLOW trial
There is an urgent need for first-line treatment options for patients with human epidermal growth factor receptor 2 (HER2)-negative, locally advanced...
