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An Acute Need Inspiration: Autoneutralization of Lupus Anticoagulants in Affected Prothrombin Times (PT) and Activated Partial Thromboplastin Times (APTT)
Lupus anticoagulants are antibodies directed to phospholipids (PL) and in particular represent an in vitro phenomenon where these antibodies bind to...
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Performance and Interpretation of Clot Waveform Analysis
The prothrombin time (PT) and the activated partial thromboplastin time (aPTT) are two basic tests for routine purposes, which are widely used in the...
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Head-to-head ex vivo comparison of clinically used direct anticoagulant drugs
An imbalance in coagulation is associated with cardiovascular events. For prevention and treatment, anticoagulants, currently mainly xabans and...
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An Overview of Heparin Monitoring with the Anti-Xa Assay
Heparin remains a critical therapy in hospitalized patients requiring anticoagulation. Unfractionated heparin (UFH) mediates its therapeutic effect...
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Analysis of clinical characteristics and risk factors for death due to severe influenza in children
ObjectiveThe study analyzed the clinical features of children who had severe influenza and discussed on the risk factors associated with death in...
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Anti-factor Xa activity, prothrombin time, and activated partial thromboplastin time in patients treated with factor Xa inhibitors
The regimens for factor Xa (FXa) inhibitors (apixaban, edoxaban, and rivaroxaban) vary with venous thromboembolism (VTE) or non-valvular atrial...
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Auto-validation of Routine Coagulation/Hemostasis Assays with Reflex Testing of Abnormal Test Results
Hemostasis laboratories play a crucial role in the diagnosis and treatment of individuals with bleeding or thrombotic disorders. Routine coagulation...
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Assays to Monitor Bivalirudin
Bivalirudin (Angiomax, Angiox) is a parenteral direct thrombin inhibitor (DTI) that is used for patients with heparin-induced thrombocytopenia (HIT),...
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The value of plasma presepsin as a diagnostic and prognostic biomarker for sepsis in Southern China
BackgroundPresepsin is a soluble CD14 subtype that has been considered as a novel marker for patients with sepsis. This study explored the clinical...
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The prognostic role of coagulation markers in the progression and metastasis of laryngeal squamous cell carcinoma
BackgroundThe application of coagulation-related markers in laryngeal squamous cell carcinoma(LSCC) remains unclear. This study explored the...
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Analysis of risk factors associated with fatal outcome among severe fever with thrombocytopenia syndrome patients from 2015 to 2019 in Shandong, China
To better understand the progression of severe fever with thrombocytopenia syndrome (SFTS), identify early predictors of mortality, and improve the...
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Coagulation markers in patients with venous thromboembolism treated with 10 mg apixaban twice daily
AbstractApixaban is used to treat venous thromboembolism (VTE) at 10 mg twice daily (BID) for 7 days, followed by 5 mg BID without dose adjustment,...
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Safety and Pharmacokinetics of Intranasally Administered Heparin
PurposeIntranasally administered unfractionated heparin (UFH) and other sulfated polysaccharides are potential prophylactics for COVID-19. The...
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Establishment and validation of a nomogram based on coagulation parameters to predict the prognosis of pancreatic cancer
BackgroundIn recent years, multiple coagulation and fibrinolysis (CF) indexes have been reported to be significantly related to the progression and...
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Ethacrynic acid is an inhibitor of human factor XIIIa
BackgroundEthacrynic acid (EA) is a loop diuretic that is approved orally and parenterally to manage edema-associated diseases. Nevertheless, it was...
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Mutation Analysis of F11 Gene in Patients with FXI Deficiency in Russia
AbstractFactor FXI is an essential participant of the blood coagulation cascade and is coded by the F11 gene, mutations in which lead to an...
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Phloretin targets SIRT1 to alleviate oxidative stress, apoptosis, and inflammation in deep venous thrombosis
Deep vein thrombosis (DVT) is a type of venous thromboembolism posing a serious threat to health on a global scale. Phloretin is a potential natural...
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Clinical characteristics and risk factor analysis of Pneumocystis jirovecii pneumonia in patients with CKD: a machine learning–based approach
Patients with chronic kidney disease (CKD) who are being treated with immunosuppressive medications are at risk for develo** Pneumocystis jirovecii ...
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Effect of low-molecular-weight heparin calcium combined with magnesium sulfate and labetalol on coagulation, vascular endothelial function and pregnancy outcome in early-onset severe preeclampsia
ObjectiveThis paper was aimed at unveiling the effect of low-molecular-weight heparin calcium (LMWH) combined with magnesium sulfate and labetalol on...
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Development of Laboratory Parameters-Based Formulas in Predicting Short Outcomes for Adult Hemophagocytic Lymphohistiocytosis Patients with Different Underlying Diseases
PurposeHemophagocytic lymphohistiocytosis (HLH) is a severe disease with high mortality. The purpose of this investigation was to build models to...
