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Dracunculiasis (Guinea Worm Disease)
Dracunculiasis, also known as guinea worm disease, is caused by the nematode Dracunculus medinensis, which infects humans typically through drinking...
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Enlarged pore of worm mesoporous silica nanoparticles improves anti-inflammatory drug absorption
Searching for an effective pore-enlarging agent to form mesoporous silica nanoparticles (MSN) with a creative surface frame is of great importance....
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Brazilian green propolis reduces worm burden and hepatic granuloma formation in a Schistosoma mansoni experimental murine model
Characterized as an acute and chronic parasitic disease, schistosomiasis mansoni has as its central pathology the formation of hepatic granulomas in...
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Why Are We Still a Worm World in the 2020s? An Overview of Risk Factors and Endemicity for Soil-Transmitted Helminthiasis
PurposeSoil-transmitted helminthiasis (STH) is one of the most common chronic infections in develo** countries associated with poor socioeconomic...
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Sanguinarine: an alkaloid with promising in vitro and in vivo antiparasitic activity against different developmental stages of Schistosoma mansoni and in silico pharmacokinetic properties (ADMET)
The objective of the study was to evaluate the in vitro and in vivo schistosomicidal activity of sanguinarine (SA) on Schistosoma mansoni and its in...
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Identification and characterisation of common glow-worm RNA viruses
The common glow-worms ( Lampyris noctiluca ) are best known for emission of green light by their larvae and sexually active adult females. However,...
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Anthelmintic Activity of Saussurea costus (Falc.) Lipsch. Against Ascaridia galli, a Pathogenic Nematode in Poultry: In Vitro and In Vivo Studies
Aim of the studyThe growing resistance of helminth parasites to currently available commercial anthelmintic drugs, combined with apprehensions...
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Loiasis
Loiasis, also known as African eye worm, is a vector-borne parasitic disease caused by the filarial nematode Loa loa and transmitted by the bite of...
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Therapeutic efficacy of candidate antischistosomal drugs in a murine model of schistosomiasis mansoni
Schistosomiasis is a neglected tropical disease associated with considerable morbidity . Praziquantel (PZQ) is effective against adult schistosomes,...
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Diagnosis of Loa loa: From Blood Identification to Innovative Approaches
Loiasis is a parasitic disease due to the filarial nematode Loa loa and transmitted to humans via the bites of a tabanid fly of the genus Chrysops....
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Using the Model Organism Caenorhabditis elegans to Explore Neuromuscular Function
The 1 mm long worm Caenorhabditis elegans is a free-living nonparasitic nematode found around the world. It offers a simple example of animal...
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Efficacy of carvacryl acetate in vitro and following oral administration to mice harboring either prepatent or patent Schistosoma mansoni infections
Schistosomiasis is a major public health problem that afflicts more than 240 million individuals globally, particularly in poor communities....
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Type I/II Immune Balance Contributes to the Protective Effect of AIF-1 on Hepatic Immunopathology Induced by Schistosoma japonicum in a Transgenic Mouse Model
Schistosomiasis is the second most debilitating neglected tropical disease in the world. Liver egg granuloma and fibrosis are the main damage of...
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Schistosoma mansoni vaccine candidates identified by unbiased phage display screening in self-cured rhesus macaques
Schistosomiasis, a challenging neglected tropical disease, affects millions of people worldwide. Develo** a prophylactic vaccine against Schistosoma...
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Salmonella Typhimurium expressing chromosomally integrated Schistosoma mansoni Cathepsin B protects against schistosomiasis in mice
Schistosomiasis threatens hundreds of millions of people worldwide. The larval stage of Schistosoma mansoni migrates through the lung and adult worms...
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Onchocerciasis Part I
Onchocerciasis, also known as river blindness, is a dermic filariasis caused by the nematode Onchocerca volvulus. The disease is found in 30 African...
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Echinostomiasis
Echinostomes are a large family of trematodes, some of which have potentials to cause zoonotic infections in humans. Echinostoma hortense and...
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Schistosomiasis: Current and Future Strategies to Develop Novel Therapeutics
A chronic human parasitic disease schistosomiasis, commonly known as bilharzia, is caused by trematode flukes belonging to the genus Schistosoma....
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Dicrocoelium spp. in cattle from Wa, Ghana: prevalence and phylogeny based on 28S rRNA
Dicrocoeliosis is a trematode infection in cattle, sheep and goats caused by the small liver fluke, Dicrocoelium spp. Though endemic in Ghana, its...
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In vitro and in vivo evaluation of cnicin from blessed thistle (Centaurea benedicta) and its inclusion complexes with cyclodextrins against Schistosoma mansoni
Schistosomiasis, caused by a blood fluke of the genus Schistosoma , afflicts over 230 million people worldwide. Treatment of the disease relies on...
